Term
| name 3 SSRIs that are first line for depression |
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Definition
| fluoxetine, paroxetine, sertraline |
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Term
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Definition
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Term
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Definition
| blocks 5-HT2 receptors and reuptake |
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Term
| which antidepressant has no effect on 5-HT? |
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Definition
| buproprion; blocks DA and NE reuptake only |
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Term
| MOA: blocks 5-HT2, 5-HT3, and alpha2 receptors |
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Definition
| mirtazapine (atypical antidepressant) |
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Term
| TCA drug interactions with tyramine, MAOI, monoamine agonists, sedatives |
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Definition
| decreases effects of tyramine, potentiates effects of MAOi, monoamine agonists, and sedatives |
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Term
| how long does it take antidepressants to work? |
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Definition
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Term
| causes tetralogy of Fallot if given in 1st trimester; very small therapeutic index |
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Definition
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Term
| 5 drugs indicated for bipolar disorder |
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Definition
| lithium, lamotrigine, carbamazepine, olanzapine, valproate |
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Term
| name 5 typical antipsychotics/neuroleptics |
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Definition
| haloperidol + "-azines" (chlorpromazine, trifluoperazine, fluphenazine, thioridazine) |
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Term
| why are atypical antipsychotics preferred over typical antipsychotics? |
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Definition
| fewer EPS side effects, improves both positive and negative symptoms |
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Term
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Definition
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Term
| atypical antipsychotic that causes hyperprolactinemia |
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Definition
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Term
| weight neutral antipsychotic |
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Definition
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Term
| name 6 atypical antipsychotics |
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Definition
| clozapine, olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole |
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Term
| motor AE of typical antipsychotics |
|
Definition
| Parkinsonism, rigidity, EPS, akathisia, tardive dyskinesia, torticollis, dystonia, neuroleptic malignant syndrome |
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Term
|
Definition
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Term
| MOA: melatonin receptor agonist |
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Definition
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Term
| first line tx for narcolepsy |
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Definition
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Term
| BZDs used for sedation or as an anxiolytic |
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Definition
| diazepam, flurazepam, temazepam, triazolam |
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Term
| AE of BZDs used for sedation |
|
Definition
| coronary vasodilation, respiratory depression, anterograde amnesia |
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Term
| BZD with intermediate onset and duration |
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Definition
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Term
| BZD with short onset and short duration |
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Definition
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Term
| BZD with rapid onset, long duration (2) |
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Definition
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Term
| binds alpha1 subunit on GABA channel (2), indicated for sedation only |
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Definition
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|
Term
| 5-HT1A partial agonist; indicated for general anxiety disorder only |
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Definition
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|
Term
| first line for anxiety disorders |
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Definition
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Term
| how do sedatives work on the sleep cycle? |
|
Definition
| increases stage 2 sleep, decreases stage 3, 4, and REM sleep |
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Term
| indications: buspirone vs. buproprion |
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Definition
| buspirone->GAD; bupropion->antidepressant |
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Term
| indications: buspirone vs. risperidone |
|
Definition
| buspirone->GAD; risperidone->atypical antipsychotic |
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Term
| indications: chloroprocaine vs. chlorpromazine |
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Definition
| chloroprocaine->local anesthetic; chlorpromazine->typical antipsychotic |
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Term
| indications: tranylcypromine vs. trihexyphenidyl |
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Definition
| tranylcypromine->MAOi for antidepressant; trihexyphenidyl->anticholinergic for PD |
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Term
| MOA: duloxetine vs. fluoxetine |
|
Definition
| duloxetine->SNRI; fluoxetine->SSRI |
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Term
| indications: ropinirole vs. risperidone |
|
Definition
| ropinirole->D2 agonist for PD; risperidone->atypical antipsychotic |
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|
Term
| indications: benzocaine vs. benztropine |
|
Definition
| benzocaine->local anesthetic; benztropine: anticholinergic for PD |
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|
Term
| indications: clonazepam vs. clozapine |
|
Definition
| clonazepam->BZD; clozapine->atypical antipsychotic |
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|
Term
| indications: phenobarbital, primidone, thiopental, methohexital |
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Definition
| phenobarbital and primidone->antiepileptic; methohexital, thiopental->anesthesia |
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