Term
Accepting that there is a difference when there really
isn’t one; false positive |
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Definition
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Term
Accepting that there is no difference when there
really is one; false negative |
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Definition
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Term
| A measure or endpoint that represents another endpoint |
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Definition
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Term
| Beginning in the present and evaluating events as they occur in the future |
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Definition
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Term
| level of statistical significance; reflects the probability a result is due to chance |
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Definition
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Term
| probability of correctly identifying a difference between treatment groups when a difference really exists in the population |
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Definition
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Term
| process of assigning patients to a study group such that each patient has an equal and independent chance of being assigned to any of the groups |
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Definition
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Term
| Range with a high probability of containing the true population value |
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Definition
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Term
| study assignment in a study is not apparent to the individual enrolling subjects into the study |
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Definition
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Term
| the endpoint for which the study is powered |
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Definition
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Term
series of questions that can estimate the probability that a particular
adverse event in a specific patient was caused by the drug in question |
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Definition
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Term
Can be completed more quickly;
Less impact form study dropouts;
Easier to conduct |
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Definition
| parallel study compared to crossover study |
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Term
The author may not be disclosing other information about less favorable outcomes observed in
other patients, or other drug or disease factors that could have influenced the results observed |
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Definition
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Term
The hypothesis that there is no
difference between interventions |
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Definition
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Term
Range with a high probability of
containing the true population value |
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Definition
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Term
| the average of all data points |
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Definition
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Term
| the middle value within a set of data points |
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Definition
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Term
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Definition
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Term
| an assessment of variability around the mean |
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Definition
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Term
Retrospective study design in which
subjects are matched with controls with
similar characteristics except the
disease state or condition in question |
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Definition
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Term
Study design in which subjects with and
without a particular risk factor are
followed for a period of time to see if
they develop a particular condition |
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Definition
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Term
| prospective study design in which subjects serve as their own control |
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Definition
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Term
| both the subject and the investigator are unaware of the subject's study group assignment in a study |
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Definition
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Term
| blinding method using multiple placebos to match the active interventions when they vary in appearance or method of administration |
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Definition
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Term
| characteristics that would make a person ineligible for participation in a study |
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Definition
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Term
| characteristics a person must have to be eligible for participation in a study |
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Definition
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Term
| study endpoint for which the study is powered |
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Definition
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Term
| study with an alpha of 0.05 |
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Definition
| there is a risk of up to 5% that the result is due to chance |
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Term
| Purpose of the Naranjo algorithm |
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Definition
| assess the probability that an adverse reaction is due to the drug in question |
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Term
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Definition
| Patient/Problem, intervention, comoparison, outcome |
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Term
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Definition
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Term
| system using some types of restrictions (tiers, generic first, limited access to some drugs) |
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Definition
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Term
| analyze the way the mean of a variable is affected by different types or combinations of factors |
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Definition
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Term
| study design that can influence the generalizability of the results |
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Definition
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Term
| study design variables that translate to reliable results |
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Definition
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Term
| study designs that enrolls only one patient |
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Definition
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Term
| A ratio describes the probability that a patient in an exposed group had an event relative to the probability that a patient in the control group had that event |
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Definition
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Term
| A study design where all arms of the study enroll patients and occur at the same time |
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Definition
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Term
| assessment of the patient cohort that completed the clinical trial with no major violations or dropouts |
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Definition
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Term
| analysis of experimental data for patterns that were not specified prior to the start of the study |
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Definition
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Term
| study endpoint for which the study is powered |
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Definition
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Term
| variability of sample means in population |
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Definition
| standard error of the mean |
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Term
| laboratory value or physical sign measured as a substitute for a clinical endpoint |
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Definition
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