Term
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Definition
| Binds 30S subunits, prevent attachment of aminoacyl-tRNA |
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Term
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Definition
| Inhibits RNA polymerase II |
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Term
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Definition
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Term
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Definition
| Inhibits ribonucleotide reductase |
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Term
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Definition
| Blocks de novo purine synthesis |
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Term
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Definition
| Inhibits thymidylate synthase (decrease dTMP) |
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Term
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Definition
| Inhibits dihydrofolate reductase (decrease dTMP) |
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Term
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Definition
| Inhibits bacterial dihydrofolate reductase (decrease dTMP) |
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Term
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Definition
| Binds 30S and inhibit formation of initiation complex and cause misreading of mRNA |
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Term
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Definition
| Inhibits 50S peptodyltransferase; blocks peptide bond formation |
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Term
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Definition
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Term
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Definition
| Block peptide bond formation |
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Term
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Definition
| Inhibits Na/K pump by binding to K site |
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Term
| Cardiac glycoside (digoxin & digitoxin) |
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Definition
| Directly inhibit Na/K ATPase (leads to inhibition of Na?Ca exchange --> Increasing Ca and INcrease contractility |
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Term
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Definition
| Binds Biotin (found in raw eggs) |
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Term
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Definition
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Term
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Definition
| Inhibits alcohol dehydrogenase (antidote for methanol and ethylene glycol poisoning) |
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Term
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Definition
| Inhibits acetaldehyde dehydrogenase |
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Term
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Definition
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Term
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Definition
| Binds to DNA inhibits RNA polymerase chain elongation in both eukaryotes and prokaryotes |
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Term
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Definition
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Term
| nitroglycerin, nitroprusside, dinitrate |
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Definition
Converted to NO, which activates guanylate cyclase, leading to increase in cGMP which activates protein kinase G.
cGMP causes smooth muscle relaxtion of blood vessels. |
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Term
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Definition
| Inhibits cGMP-dependent phosphodiesterase (PDE5), leading to cGMP build up causing smooth muscle relaxation |
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Term
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Definition
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Term
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Definition
| Increases vWF release from Weibel-Palade bodies of endothelial cells |
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Term
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Definition
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Term
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Definition
| Blocks activation of plasminogen |
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Term
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Definition
| Activates Antithrombin III |
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Term
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Definition
| adenosine deaminase inhibitor |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Competitive specific type II 5-alpha reductase inhibitor |
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Term
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Definition
| Inhibitor of androgen uptake and binding to receptors |
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Term
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Definition
| xanathine oxidase inhibitor |
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Term
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Definition
| Inhibits reabsorption of uric acid in PCT |
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Term
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Definition
| Binds and stabilizes tubulin to inhibit polymerization , impairing leukocyte chemotaxis and degranulation |
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Term
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Definition
| Folic acid analog that inhibts dihydrofulate reductase |
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Term
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Definition
| Pyrimindine analog that complexes folic acid and inhibits thymidylate synthase |
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Term
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Definition
| Pyrimidine analog -> inhibition of DNA polymerase |
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Term
Azathiprine
6-mercaptopurine (6-MP)
6-Thiogunaine (6-TG) |
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Definition
| Purine analog -> decreases de novo purine synthesis |
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Term
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Definition
| CCR5 co-receptor antagonist (prevemnts interaction w/ gp-120) |
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