Term
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Definition
| an agent that increases formation of urine |
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Term
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Definition
| an agent that preferentially aids excretion of Na |
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Term
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Definition
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Term
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Definition
| what is the main therapeutic aim of diuretics? |
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Term
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Definition
the main action of this weak diuretic is to inhibit carbonic anhydrase.
It's used in glaucoma, mountain sickness, and it facilitates the excretion of acidic drugs. |
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Term
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Definition
| this diuretic is filtered at the glomerulus, but not reabsorbed along the nephron |
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Term
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Definition
| this osmotic diuretic is used in cerebral edema, hydrocephalus, brain surgery, and acute renal failure |
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Term
| congestive heart failure, HTN |
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Definition
| What is mannitol contraindicated in? |
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Term
| the ascending loop of henle |
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Definition
| what is the site of loop diuretics? |
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Term
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Definition
| this loop diuretic has a high ceiling and is close to 100% effective |
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Term
| furosemide (loop diuretic) |
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Definition
| this drug inhibits the Na/K symporter and has a powerful natriuretic effect by excretion of high percentage of filtered Na. Also produces kaliuresis |
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Term
| hyponatremia, hypokalemia, ototoxicity |
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Definition
| adverse effects of furosemide |
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Term
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Definition
| what is the site for thiazide diuretics? |
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Term
| Late DT and collecting tubule |
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Definition
| what is the site for K-sparing diuretics? |
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Term
chlorothiazide
hydrochlorothiazide |
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Definition
| name the thiazide diuretic drugs |
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Term
| HTN, edema, nephrogenic diabetes insipidus |
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Definition
| what are thiazides used for? |
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Term
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Definition
| This K+ sparing drug is aldosterone dependant |
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Term
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Definition
| These K+ sparing diuretics are aldosterone-independent |
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Term
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Definition
| what is the adverse effect Spironolactone (K+ sparing) |
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Term
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Definition
| these diuretics are used in HTN, treatment or prevention of hypokalemia induced by loop and thiazide diuretics |
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Term
DEmeclocyclin
(collecting duct diuretic) |
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Definition
| this diuretic is a non-competitive ADH Antagonist used in the syndrome of inappropriate ADH secretion |
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Term
Desmopressin
(cortical collecting duct antidiuretic) |
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Definition
| this drug is a synthetic analogue of ADH and produces a concentrated urine with increased osmolality. It is the drug of choice for central diabetes insipidus |
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Term
Conivaptan
(Vasopressin Antagonist) |
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Definition
| This drug ia an antagonist at V1 and V2 ADH receptors it reduces H2O reabsorption and increases plasma Na concentration. It's used for hyponatremia. |
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