Term
| What percent of body weight is comprised of water? |
|
Definition
|
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Term
| List fluid compartment from highest to lowest. |
|
Definition
| Intracellular > Extracellular > Plasma |
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Term
|
Definition
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Term
| What cells regulates renin release? |
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Definition
| Juxtaglomerular cells and macula densa cells. |
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Term
| Which part of the kidney is responsible for the most water absorption? |
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Definition
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Term
| Where is the water absorbed in the Loop of Henle? |
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Definition
| Water is absorbed in the thin ascending Loop of Henle. The thick ascending Loop of Henle is water impermeable. |
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Term
| Whats so special about the distal tubule? |
|
Definition
-Early portion of DCT uses Na/CL symporter activity.
-Later segment resabsorb Na+ in via an aldosterone-dependent manner. |
|
|
Term
| How does aldosterone decrease water excretion? |
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Definition
| Aldosterone increase formation of Na/K ATPase proteins in DCT and increases Na+ reabsorption. |
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Term
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Definition
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Term
| What is the most commonly used diuretic? |
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Definition
|
|
Term
| What is the MoA of thiazides? |
|
Definition
-Block Na/CL reabsorption in PCT.
- |
|
|
Term
| Where in the nephron does thiazides work? |
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Definition
|
|
Term
| Which diuretic agents causes loss of K? |
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Definition
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|
Term
| What are some major side effects of thiazides? |
|
Definition
-Hypokalemia
- decrease inuslin and worsen diabetes mellitus
-hyperuricemia
-lithium toxicity |
|
|
Term
| Which diuretic can be used for open angle glaucoma? |
|
Definition
|
|
Term
| What limits the use of carbonic anhydrase as a diuretic? |
|
Definition
|
|
Term
Dorsalamide
Acetazolamide
Methazolamide |
|
Definition
|
|
Term
Furosemide
Bumetanide
Torsemide
Ethacrynic Acid |
|
Definition
| Loop Diuretic or High Ceiling Diuretic |
|
|
Term
|
Definition
| Block CL dependent Na/K in Loop of Henle. |
|
|
Term
| What is ethacrynic acid used for? |
|
Definition
|
|
Term
| What happens if you use thiazides on a patient with low GRF? |
|
Definition
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