Term
|
Definition
Diabetes insipidus, vasodilatory shock,
gi bleeding |
|
|
Term
|
Definition
Growth hormone deficiency
HIV wasting |
|
|
Term
|
Definition
acromegaly (excess GH)
metastatic carcinoid tumor (controls diarrhea)
VIPoma |
|
|
Term
| desmopressin/ vasopressin adverse effects |
|
Definition
increase BP
fever
vertigo
uterine cramping
nasal irritation
tremor, sweating |
|
|
Term
| somatropin adverse effects |
|
Definition
headache, muscle pain
injection site inflammation
hypo & hyperglycemia |
|
|
Term
| somatropin contraindications |
|
Definition
children w/ closed growth plates,
tumors
acute illnesses |
|
|
Term
| octreocide adverse effects |
|
Definition
fatigue
increase or decrease in blood glucose
dyspnea
joint pain
cardiovascular conduction abnormalities |
|
|
Term
| With ocetreocide the provider may order an _______ prior to use. |
|
Definition
| ECG- due to conduction abnormalities |
|
|
Term
| desmopressin- check for history and use caution with what conditions |
|
Definition
| seizures, asthma, or cardiovascular disease |
|
|
Term
|
Definition
Diabetes insipidus, hemophilia
type 1 von Willebrand's disease |
|
|
Term
| vasopressin IV infiltration may lead to ______. |
|
Definition
| severe vasoconstriction, tissue necrosis. |
|
|
Term
| what are the three rapid acting insulins? |
|
Definition
|
|
Term
| Rapid-acting insulin onset, pk, duration |
|
Definition
|
|
Term
| short acting insulin onset, pk, duration |
|
Definition
|
|
Term
| intermediate-acting (NPH) onset, pk, duration |
|
Definition
|
|
Term
| which insulin is referred to as a basal insulin |
|
Definition
|
|
Term
| vasopressin mimics what hormone? |
|
Definition
|
|
Term
| Which type of diabetes does metformin treat? |
|
Definition
|
|
Term
| what drug is the first-line drug for type 2 diabetes |
|
Definition
|
|
Term
|
Definition
|
|
Term
| metformin works by decreasing glucose production by the ______? |
|
Definition
|
|
Term
| most common adverse reactions of metformin? |
|
Definition
| gastrointestinal (bloating, nausea, cramping, diarrhea) |
|
|
Term
| Mechanism of action: glinide class? |
|
Definition
| increase insulin secretion from the pancreas. |
|
|
Term
| Glinides can't be used along with which other diabetic drug class? |
|
Definition
sulfonylureas
(because they have a similar action) |
|
|
Term
true/false:
glinides must be given with each meal? |
|
Definition
| true (they have a short duration) |
|
|
Term
| metformin is contraindicated in patients with what three conditions? |
|
Definition
| renal disease, alcoholics, cardiopulmonary disease |
|
|
Term
| adverse effects of glinides? |
|
Definition
| hypoglycemia (esp if not taken w/ food) |
|
|
Term
| contraindications of glinides and sulfonylureas? |
|
Definition
| hypoglycemia and conditions that predispose pt to hypoglycemia (NPO, advanced age) |
|
|
Term
| glipizide works best given ____ minutes before a meal |
|
Definition
|
|
Term
| thiazolidinedoines are commonly reffered to as ________? |
|
Definition
|
|
Term
| pioglitazone can be used with insulin? t/f |
|
Definition
|
|
Term
| thiazolidinediones (glitones) mode of action? |
|
Definition
| enhance the sensitivity of insulin receptors, stimulate peripheral glucose uptake/storage |
|
|
Term
| thiazolidinediones adverse effects? |
|
Definition
| increase risk of heart failure, peripheral edema and weight gain, reduced bone mineral density |
|
|
Term
| Alpha-Glucosidase inhibitor drug |
|
Definition
|
|
Term
| sitagliptin, saxagliptin, linagliptin drug class? |
|
Definition
| Dipeptidly Peptidase IV inhibitors |
|
|
Term
| How do DPP-IV inhibitors work? |
|
Definition
| delaying the breakdown of incretin hormones |
|
|
Term
| acarbose should be taken when? |
|
Definition
| with the first bit of each meal |
|
|
Term
| DPP-IV drug adverse effects? |
|
Definition
| upper respiratory infection, headache and diarrhea |
|
|
Term
| Which antidiabetic drug should be discontinued at least 48 hours prior to any radiologic study requiring such contrast media and should be held for at least 48 hours after the procedure? |
|
Definition
|
|
Term
| what drug class is pramlintide? how/when is it administered? |
|
Definition
| amylin agonist, injectable, taken before major meals |
|
|
Term
| which type of diabetes is amylin agonists (pramlintide) used to treat? |
|
Definition
|
|
Term
| how does pramlintide work/ mechanism of action? |
|
Definition
slows gastric emptying
suppress glucagon secretion
increase satiety |
|
|
Term
| what class does exenatide belong to? |
|
Definition
|
|
Term
| incretin mimetics mechanism of action? |
|
Definition
stimulates insulin secretion
reduce postprandial glucagon production
slow gastric emptying
increase satiety |
|
|
Term
|
Definition
anti-inflammatory,
immunosuppressant (lupus, RA, MS, auto-immune flare-up, asthma |
|
|
Term
| Name two glucocorticoids? which one is the preferred oral? which is the most common injectable? |
|
Definition
prednisone
methylprednisone |
|
|
Term
| adverse side effects of glucocorticoids? |
|
Definition
| moon face, hunger, weight gain, edema, mood swings, hyperglycemia, psychosis |
|
|
Term
| Glucorticoids cause edema so they should be used with caution in patients with _______? |
|
Definition
|
|
