Term
Topical - directly to surface of skin
Subcutaneous - Inserted into fatty tissue just beneath skin surface
Transdermal - incorporated into an adhesive patch and applied to the epidermis |
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Definition
| Major route of drug administration |
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Term
Nature of skin - thickness/hydration
Drug conc/properties |
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Definition
| Factors influenciing Topical route of drug administration |
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Term
Route of preference for many protein drugs eg insulin
relatively simple and painless |
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Definition
| advantages of Subcutaneous route of drug administration |
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Term
user friendly, convenient, painless
rapid termination of action
avoidance of first pass metabolism |
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Definition
| advantages of transdermal route of drug administration |
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Term
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Definition
| Widely used in treatment of atopic eczema |
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Term
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Definition
Gram positive cocci in clusters
Can grow both aerobically and anaerobically |
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Term
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Definition
| Common human pathogen, produces plasma clotting enzymes eg coagulase, causes would,skin,joint and bone infections |
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Term
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Definition
| Antibiotic resistant strain of Staph Aureus |
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Term
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Definition
| Not usually pathogenic, causes infection in assiociation with artificial joints, heart valves and IV catheters |
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Term
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Definition
| Common cause of UTIs in women of chld bearing age |
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Term
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Definition
| Gram positive cocci in chains "strips" |
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Term
Staph aureus
Strep Pyogenes |
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Definition
| Bacterial skin infections (2) |
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Term
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Definition
| Treatment of staph aureus skin infection |
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Term
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Definition
| Treatment of Strep pyogenes skin infection |
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Term
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Definition
| Diagnose Bacterial skin infection |
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Term
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Definition
| Underlying problem is usually vascular, should only take swabs from these if signs of cellulitis/infection |
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Term
Strep pyogenes
Staph aureus
anaerobes |
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Definition
| Organisms worth treating for with leg ulcers (3) |
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Term
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Definition
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Term
Other infected individuals
Animals |
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Definition
| Sources of fungal infection (2) |
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Term
Woods light
skin scrapings
nail clippings
hair sample |
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Definition
| Investigations to confirm diagnosis of fungal infection |
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Term
CANESTAN cream for small area
Oral TERBINAFINE OR ITRACONAZOLE for extensive infection |
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Definition
| Treatmeant of fungal infection |
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Term
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Definition
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Term
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Definition
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Term
| Chicken pox (childhood) and shingles (adult) |
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Definition
| Viral infections due to varicella zoster virus |
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Term
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Definition
| Viral infection with dermatomal distribution |
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Term
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Definition
| Recurring virus that causes extensive ulceration in and around the mouth |
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Term
Swab with viral transport medium
Antibody test where site inaccesible for swab |
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Definition
| Lab confirmation of viral infection |
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Term
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Definition
| Common viral infection, mainly seen in children. Also associated with cervical cancer. |
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Term
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Definition
| Increased thickness of keratin |
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Term
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Definition
| Persistence of nuclei in the keratin layer |
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Term
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Definition
| Increase thickness of epithelium |
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Term
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Definition
| Irregular epithelial thickening |
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Term
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Definition
| odema fluid between squamous cells |
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Term
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Definition
| Non infective inflammatory skin condition that shows itching, redness and scaling, effecting flexure areas behind the knees and elbows |
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Term
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Definition
| Important type of dermatitis common case with irritants and allergens (type 4 hypersensitivity) |
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Term
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Definition
| Chronic, non infectious, inflammatory condition characterised by red plaques topped by silvery scales in extensor areas - elbow and knees |
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Term
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Definition
| Percentage of population affected by psoriasis |
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Term
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Definition
Inheritance in psoriasis is...
and what percent have a family history |
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Term
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Definition
| Distribution reflects sebaceous gland sites. |
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Term
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Definition
| Acne can be caused by increased production of this a puberty |
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Term
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Definition
| Rare. severe auto immune blistering disorder affectin skin and mucous membranes |
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Term
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Definition
| Treatment for bullous pemphigus |
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Term
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Definition
| Sub epidermal blistering, common in elderly |
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Term
| Acantholysis - lysis of intercellular adhesion sites |
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Definition
| Common to all variatns of bullous pemphigus but not to bullous pemphigoid |
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Term
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Definition
| In bullous pemphigoid what shows linear IgG deposited around the basal membrane |
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Term
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Definition
| Formed when the normal ratio of melanocytes to keratinocytes breaksdown at number of cutaneous sites during infancy |
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Term
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Definition
| Skin tumour More common in females, due to UVB exposure, arise in skin |
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Term
| Ulceration, bleeding, irregular pigmentation, change in shape, development of nodule |
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Definition
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Term
| Surgical excision. Difficult to treat if advanced. |
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Definition
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Term
Avoid blistering in sun
Use UV block |
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Definition
| How to prevent getting melanoma |
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