Term
| Adverse food rxn can occur through _____ or _____. |
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Definition
| Immunological rxn (HS); non-immunological rxn (Food Intolerance) |
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Term
| Food intolerance occurs through content of _____ or _____. |
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Definition
| Histamine; Histamine-releasing factors |
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Term
| Are more cases of adverse food rxn probably HS or food intolerance? |
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Definition
|
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Term
| What is probably involved in the pathogenesis of food allergy? |
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Definition
|
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Term
| What type of CS (generally) are seen w/ food allergy? |
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Definition
| Dermatologic, GI, or both |
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Term
| Food allergy occurs w/ _____% frequency of atopic dermatitis. |
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Definition
|
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Term
| What breeds of dog are predisposed to food allergy? |
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Definition
| GSD, Pug, Rhodesian Ridgeback |
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Term
| What are the manifestations of chronic GI dz from food allergy? |
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Definition
|
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Term
| What are some mild GI signs associated w/ food allergy? |
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Definition
| Occasional loose stools, increased frequency of defecation (>2-3x/d), increased flatulence |
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Term
| What GI histopath is possible w/ food allergy? |
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Definition
| Eosinophilic gastroenteritis a/o lymphocytic-plasmacytic enteritis |
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Term
| What derm sign is almost always seen w/ food allergy? |
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Definition
|
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Term
| _____% of food allergy cases commence prior to 1yo. |
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Definition
|
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Term
| What are the primary eruptions of food allergy? |
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Definition
| Usually papules; rarely wheals |
|
|
Term
| What secondary infection is often seen w/ food allergy? |
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Definition
| Staphylococcal (typically relapses quickly after abx Tx) |
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Term
| _____ is affected less frequently in food allergy, and _____ is suggestive. (Distribution) |
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Definition
| Volar aspect of feet; Perianal involvement |
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|
Term
| In what % of food allergy cases is otitis externa seen? |
|
Definition
|
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Term
| In contrast to atopic dermatitis, otitis externa associated w/ food allergy may commence _____. |
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Definition
|
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Term
| _____ is an unreliable diagnostic tool for food allergy. |
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Definition
|
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Term
| What is the value of in vitro tests for allergen-specific IgE a/o IgE? |
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Definition
| (Not Dx) Selection of an appropriate hypoallergenic dietary trial |
|
|
Term
| What Ab is higher in food allergic dogs? |
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Definition
|
|
Term
| For which Ab is serology available? |
|
Definition
|
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Term
|
Definition
| Sensitive & specific test where native allergen is kept in contact w/ skin for 48h |
|
|
Term
| What is the only way to confirm Dx of food allergy? |
|
Definition
| Hypoallergenic diet trial followed by provocation |
|
|
Term
| What is the gold standard for hypoallergenic diet trial? |
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Definition
|
|
Term
| How long can it take before improvement is seen w/ a hypoallergenic diet trial? |
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Definition
|
|
Term
| What % of food allergy cases are picked up by commercial single-source protein diets? |
|
Definition
|
|
Term
| In what % of cases are hydrolysate diets effective? |
|
Definition
|
|
Term
| When provoked w/ the original diet, how long does it take for relapse of food allergy? |
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Definition
|
|
Term
| What is the most common food allergen? What cross-reacts with it? |
|
Definition
| Beef; Lamb, Dairy, Venison |
|
|
Term
| What is the best therapy for food allergy? |
|
Definition
| Maintain on commercial hypoallergenic diet (Single-source protein or hydrolyzed protein) |
|
|
Term
| When should home-prepared diet be used as Tx? |
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Definition
| If a commercial diet is ineffective |
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Term
| Contact dermatitis can be either _____ or _____, but there is much overlap. |
|
Definition
| Irritant contact; Allergic contact |
|
|
Term
| What type of Ag are usually involved in allergic contact dermatitis? |
|
Definition
| Haptens (simple chemicals) that become complete Ag's on union w/ host proteins |
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|
Term
| What cells are involved w/ Ag presentation in allergic contact dermatitis? What type of HS is involved? |
|
Definition
| Langerhans' cells; Type 4 (CMI) |
|
|
Term
| What inside allergens are implicated in allergic contact dermatitis? |
|
Definition
| Detergents, dyes, anti-oxidants used in carpet manufacture |
|
|
Term
| What external allergens are involved in allergic contact dermatitis? |
|
Definition
| Grass, Weeds, Weed killers, Fertilizers |
|
|
Term
| When is foliage more allergenic? |
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Definition
|
|
Term
| Allergic contact dermatitis is almost exclusively in _____, w/ occasional cases in _____. |
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Definition
|
|
Term
| Allergic contact dermatitis occurs w/ _____% the frequency of atopic dermatitis. |
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Definition
|
|
Term
| On what parts of the body is allergic contact dermatitis manifested? |
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Definition
|
|
Term
| What is the primary eruption in allergic contact dermatitis? How often is it present? |
|
Definition
|
|
Term
| Allergic contact dermatitis is always _____, but variably so. |
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Definition
|
|
Term
| What occurs in chronic cases of allergic contact dermatitis? |
|
Definition
| Hyperpigmentation; Lichenification |
|
|
Term
| What secondary infection is commonly present w/ allergic contact dermatitis? |
|
Definition
| Staphylococcal (restricted to involved area) |
|
|
Term
| What is the best confirmation of allergic contact dermatitis Dx? |
|
Definition
| Histopathological changes |
|
|
Term
| In attempting to Dx allergic contact dermatitis, what will also improve if the dog is kenneled? |
|
Definition
|
|
Term
| How is the allergen implicated in allergic contact dermatitis? |
|
Definition
| Selective environmental challenge; Patch tests |
|
|
Term
| What is the Tx for allergic contact dermatitis? |
|
Definition
| Remove allergen; Remove pet from environment; Oral corticosteroids; Topical corticosteroids; Pentoxifylline |
|
|
Term
| What is the best topical corticosteroid for allergic contact dermatitis? |
|
Definition
|
|
Term
| What insects are involved w/ hymenoptera HS? |
|
Definition
|
|
Term
| What mediates the anaphylactic rxn in hymenoptera HS? What is a possible result? |
|
Definition
|
|
Term
| What causes local swelling in hymenoptera HS? Where is it life-threatening? |
|
Definition
| Angioedema; Oropharyngeal region |
|
|
Term
| What Tx are used for anaphylaxis? |
|
Definition
| IV epinephrine w/ IV corticosteroids |
|
|
Term
| What Tx is used for angioedema? |
|
Definition
| Injectable corticosteroids (IM) |
|
|
Term
| With what HS are similar rxn to hymenoptera HS seen? |
|
Definition
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