Term
| What is the most common cutaneous malignancy? |
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Definition
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Term
| Describe BCC. Who is it most common in? |
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Definition
| Locally invasive, usu. slow-growing, rarely metastasizes. >age 40, fair skin. |
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Term
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Definition
| Nodular, Pigmented, Superficial, Micronodular, and Morpheaform. |
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Term
| What is the most common type of BCC? Describe it. |
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Definition
| Nodular. Pearly pink paules, often ulcerate, bleed, and become crusted |
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Term
| Why is the BCC pigmented in the pigmented type? |
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Definition
| It contains melanin. May resemble malignant melanoma. |
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Term
| What is the least aggressive form of BCC? Describe it. |
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Definition
| Superficial. Lesions are flatter, not as deeply invasive, MC on truck and extremities |
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Term
| What is the diff. b/t micronodular and nodular BCC? |
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Definition
| Micronodular is clinically similar but histologically extends further making recurrence more frequent |
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Term
| What is the most subtle and least common form of BCC? Describe it. |
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Definition
| Morpheaform (sclerosing) -resembles scar tissue, extensive, more aggresive and most difficult to tx. |
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Term
| What tx for BCC is an option for well-defined, small nodular and superficial types, but causes a very slow healing wound? |
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Definition
| Electrodessication and Curettage (ED&C) |
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Term
| What is the best option for recurrent or aggressive tumors and is the TOC for morpheaform BCC? |
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Definition
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Term
| What tx is useful for BCC difficult to tx surgically and pts unwilling to undergo surgery? |
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Definition
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Term
| What is a common, persistent keratotic lesion w/ malignant potential that is most common on sun-exposed areas? |
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Definition
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Term
| About 10-20% of AK cases progress to ____ over several yrs. |
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Definition
| Invasive squamous cell CA (SCC) |
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Term
| Describe physical appearance of AK. |
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Definition
| Initially poorly defined area of redness w/ thin scale that thickens and becomes yellow over time |
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Term
| What tx can be used for solitary AK lesions? Diffuse lesions? |
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Definition
| Cryotherapy. Topical 5-FU or imiquimod |
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Term
| An invasive, primary cutaneous malignancy arising from keratinocytes of skin or mucosa that is the 2nd most common skin CA? |
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Definition
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Term
| Where does SCC typ. occur on the body? |
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Definition
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Term
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Definition
| Red lesions w/ poorly defined base and yellow-white scale. |
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Term
| What is a very superficial SCC that is intraepidermal? Does it metastasize? |
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Definition
| SCC in situ (Bowen's). No but can be invasive if untx. |
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Term
| A rapidly growing crateriform nodule, considered a low-grade SCC? |
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Definition
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Term
| Peak incidence of keratocanthoma? Areas of distribution? |
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Definition
| Ages 50-70. Face, neck, dorsal hands and sun-exposed areas. |
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Term
| Describe skin findings in keratocanthoma. |
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Definition
| Solitary lesion w/ keratotic plug that gives char. volcano shape. |
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Term
| What is the only skin CA w/ a genetic component? |
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Definition
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Term
| Melanoma is the most common malignancy in what group? |
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Definition
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Term
| What is the most common early sx of melanoma? |
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Definition
| Itchy, but most are asymptomatic |
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Term
| what is the most importane warning sign in melanoma? |
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Definition
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Term
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Definition
| In situ melanoma, usu. flat w/ irregular border, brown w/ pigment variation. nodules and ulcers may indicate local invasion. |
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Term
| what are the only rec. methods of bx on suspicious lesions? |
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Definition
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Term
| What means a better prognosis in melanoma? |
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Definition
| The thinner the breslow depth at the time of dx |
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Term
| What causes Kaposi's sarcoma? |
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Definition
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Term
| Describe classic Kaposi's sarcoma. |
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Definition
| Sporadic and slowly progressive occuring mainly in men 50-70yo of E. European or MEditerranean descent. |
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Term
| Who is at increased risk of dev. Kaposi's sarcoma? |
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Definition
| Organ transplant pts, AIDS pts |
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Term
| Describe skin lesions in Kaposi's sarcoma. |
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Definition
| Purple patches. In classic on lower legs and progress proximally. In AIDS pts on face, torso, and oral mucosa. |
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Term
| What is seen on skin bx in Kaposi's sarcoma? |
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Definition
| Neoplastic spindle-shaped cells |
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Term
| Common, benign, brown macules occuring on sun-exposed skin that appear in childhood as ephelides (freckles)? |
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Definition
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Term
| Flat or raised brown to tan macules, MC in children? |
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Definition
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Term
| Slightly or markedly raised pigmented papules. |
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Definition
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Term
| Commonly elevated, fleshy and slightly or moderately pigmented that may have coarse, dark hairs growing from them? |
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Definition
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Term
| Sharply defined tan to brown background patch containing several small monomorphic slightly raised dark brown nevi? |
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Definition
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Term
| Solitary bluish macules or papules usually on the head, neck, or buttocks? |
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Definition
|
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Term
| Usually reddish pink, dome-shaped, smooth papule. |
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Definition
| Spitz nevus (spindle cell nevus) |
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Term
| A pre-existing nevus that dev. a rim of hypopigmentation. |
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Definition
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Term
| Aquired brown hyperpigmentation of the face and neck, AKA the mask of pregnancy. |
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Definition
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Term
|
Definition
| 1)Sun avoidance 2)Bleaching creams containing hydroquinone 3)Azelaic acid during pregnancy |
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