Term
|
Definition
| progressive loss of brain function characterized by memory loss, confusion, and dementia |
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Term
|
Definition
| progressive weakness and wasting of muscles caused be destruction of motor neurons |
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Term
|
Definition
| autosomal dominant genetic disorder resulting in progressive dementia and involuntary, spasmodic movements of limb and facial muscles |
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Term
|
Definition
| demyelination of neurons in the CNS resulting in progressive weakness, visual disturbances, mood alterations, and cognitive deficits |
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Term
|
Definition
| progressive loss of dopamine in the CNS, causing tremor, muscle rigidity, and abnormal movement and posture |
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Term
|
Definition
| parkinson's med Levadopa takes _____ to see maximum effects |
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Term
|
Definition
| antiparkinsons drugs have ______ effects |
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Term
|
Definition
| most serious side effect of antiparkinsons meds |
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Term
|
Definition
| involuntary, forcible, rapid, jerky, movements that may be subtle or become confluent, markedly altering normal patterns of movement |
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Term
| carbidopa-levodopa (Sinemet) |
|
Definition
drug that prevents the metabolism of levodopa,
- enhances dopamine action |
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Term
|
Definition
| chemical precursor to dopamine |
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Term
|
Definition
| levadopa dose can be reduced by _____ if given with carbidopa |
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Term
|
Definition
| levadopa can't be used in pts w/ _____ or using __ |
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Term
|
Definition
| foods high in ____ reduce the efforts of levodopa |
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Term
|
Definition
| ____ is a normal s/e of dopaminergic meds |
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Term
|
Definition
| anticholinergics used to treat parkinsons in elderly beause less s/e |
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|
Term
| Benadryl - benztrophine(Cogentin) |
|
Definition
| 2 drugs used to control extrapyramidal disorders |
|
|
Term
amantadine
digoxin
Haldol
phenothiazines |
|
Definition
| 4 drugs that antiparkinson's cholinergic blockers interact with |
|
|
Term
| acetylcholinesterase inhibitors |
|
Definition
| alzheimers disease is treated with ______ |
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|
Term
|
Definition
| preferred drug for mild to moderate dementia |
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|
Term
nausea
diarrhea
muscle cramps
weight loss |
|
Definition
| donepezil (Aricept) may cause ___ (4) |
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Term
|
Definition
| new drug for alzheimers that prevents damage to brain neurons associated with excess glutamate release |
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Term
|
Definition
| alzheimers drug that causes hepatotoxicity |
|
|
Term
aricept
exelon
cognex
reminyl |
|
Definition
| four alzheimers drugs used to increase acetylcholine in CNS by inhibiting breakdown of neuronal pathways and slowing destruction |
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Term
|
Definition
| a combination of ____ and ___ shows best results for alzheimers in that it slows the symptoms |
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Term
|
Definition
| alzheimers drugs focus on improving _____ |
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Term
|
Definition
| drug given 3-4 times per day on an empty stomach |
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Term
|
Definition
| w/in ___ of d/c anticholinesterase all benefits are lost |
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Term
|
Definition
| herbal supplement used for improving memory |
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Term
|
Definition
| drug type used to decrease the overall relapse rate of MS |
|
|
Term
| interferon beta la(avonex, rebif) |
|
Definition
| example of immunosupressant drug used for MS |
|
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Term
|
Definition
| ______ should be used cautiously in suicidal tendancies, depression, bone marrow depression, seizure and thyroid disorders, liver problems |
|
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Term
|
Definition
| _____ can cause alopecia which is ussually temporary |
|
|
Term
modafinin(Provigil)
amantadine (symmetrel) |
|
Definition
| 2 drugs used to treat fatigue, memory loss, and progressive weakness of MS |
|
|
Term
|
Definition
| drug used to treat insomnia, anxiety, and sensitivity to pain of MS |
|
|
Term
| Methylprednisolone (Solumedrol) |
|
Definition
| drug used to treat the acute inflammation of the CNS system with MS |
|
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Term
|
Definition
| rapidly repeating muscle spasms |
|
|
Term
|
Definition
|
|
Term
| upper motor neuron activity |
|
Definition
| many muscle relaxants treat muscle spasms by inhibiting _________ causing sedation or altering simple reflexes |
|
|
Term
baclofen(Lioresal)
diazepam(Valium) |
|
Definition
| two drugs that relax muscles by acting on the CNS system to interfere with the release of Ca ions |
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Term
|
Definition
| muscle relaxant that acts directly on the muscles, not the CNS |
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Term
|
Definition
| neuromuscular blocking agents block the effect of ________ at the receptor |
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Term
|
Definition
| neuromuscular blocking agents bind to ______ receptors located on the surface of skeletal muscle |
|
|
Term
| nicotinic blocking agents |
|
Definition
| another name for neuromuscular blockers |
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Term
|
Definition
| neuromuscular blocking agents are anticholinergic or cholinergic |
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|
Term
|
Definition
| neuromuscular blockers prevent _____ muscle contraction |
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Term
|
Definition
neuromuscular blockers that competes with acetylcholine for the receptor
- muscle remains relaxed |
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|
Term
|
Definition
neuromuscular blockers that bind to the acetylcholine receptor
- muscle is continuously depolarized |
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