Term
|
Definition
| metabolizes amiodarone, flecainide, and digitoxin |
|
|
Term
|
Definition
| >0.1ng/ml abnormal, indicates MI/trauma/surgery/CHF/myocarditis/pulmonary embolism/sepsis |
|
|
Term
|
Definition
|
|
Term
|
Definition
| >100pg/ml abnormal, indicaets CHF/ACS/renal failure/pulmonary embolism/cor pulmonale |
|
|
Term
|
Definition
| 3x higher than BNP in CHF |
|
|
Term
|
Definition
| move Ca2+ between fibrils |
|
|
Term
|
Definition
| covers the active site of actin |
|
|
Term
|
Definition
| binds tropomyosin, moves 30o when activated |
|
|
Term
|
Definition
|
|
Term
|
Definition
| binds Ca2+, allows for contraction when Ca2+ bound |
|
|
Term
|
Definition
| heads form cross-bridges with actin, Pi release is rate-limiting step |
|
|
Term
|
Definition
| subunits that compromise ion channels (Cx40>Cx43>Cx45>Cx30.2) |
|
|
Term
|
Definition
| binds Ca2+ and opens Ca2+ channels out of sarcoplasm |
|
|
Term
|
Definition
| Ca2+ channels from cytosol into SR |
|
|
Term
|
Definition
| packs Ca2+ in SR close to RyR2 to facilitate release |
|
|
Term
|
Definition
| blocks Ca2+ movement into SR via SERCA |
|
|
Term
|
Definition
| inactivates phospholamban, increases internal Ca2+ (downstream of catecholamines) |
|
|
Term
| Na+/Ca2+ Exchangers (CNX) |
|
Definition
| decrease intracellular Ca2+ |
|
|
