Term
|
Definition
| formoterol (long acting beta agonist) |
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|
Term
|
Definition
| salmeterol (long acting beta agonist) |
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|
Term
|
Definition
| ipratropium (short acting anticholinergic) |
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|
Term
|
Definition
| tiotropium (long acting anticholinergic) |
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|
Term
|
Definition
| fenoterol/ipratropium (short acting beta agonist + anticholinergic) |
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|
Term
|
Definition
| ipratropium/albuterol (short acting beta agonist + anticholinergic) |
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|
Term
|
Definition
| theophylline (methylxanthines) - tends to be less effective and less well tolerated compared to long acting bronchodilators |
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| formoterol/belclometasone (long acting beta agonist + ICS) |
|
|
Term
|
Definition
| formoterol/budesonide (long acting beta agonist + ICS) |
|
|
Term
|
Definition
| formoterol/mometasone (long acting beta agonist + ICS) |
|
|
Term
|
Definition
| salmeterol/fluticasone (long acting beta agonist + ICS) |
|
|
Term
| How do beta agonists work? |
|
Definition
| by stimulating adenyl cyclase --> increases cAMP concentrations and decreases the release of mediators |
|
|
Term
| How do anticholinergics work? |
|
Definition
| suppresses the increase in cGMP (because ACH interacts with the muscarinic receptors on bronchiole smooth muscles) |
|
|
Term
| How do PDE4 inhibitors work? |
|
Definition
| by selectively inhibiting PDE4, which is a major cAMP metabolizing enzyme. Essentially, it increases cAMP |
|
|
Term
|
Definition
|
|
Term
| How do methylxanthines work? |
|
Definition
| unsure but it causes smooth muscle relaxation and suppression of airway stimuli |
|
|
Term
|
Definition
| roflumilast (PDE4 inhibitor) |
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|
