Term
|
Definition
| localized infection between the dura mater and the skull or vertebral column |
|
|
Term
| What can cause intracranial epidural abscess |
|
Definition
| frontal sinusitis, craniotomy, or mastoiditis, osteomyelitis and subdural empyema |
|
|
Term
| How are spinal epidural abscess disseminated |
|
Definition
| Hematogenous spread, direct seeding of epidural space; Vertebral osteomyelitis with extention to the epidural space |
|
|
Term
| What is spinal epidural abscess commonly assoc. with |
|
Definition
Diabetes mellitus
IV drug abuse
Chronic renal failure
Alcoholism
Cancer |
|
|
Term
| What bact. causes most cases of spinal epidural abscess |
|
Definition
| Staph aureus, followed by Strep, Pseudomonas aeruginosa + E. coli |
|
|
Term
| Where in children is spinal epidural abscess commonly found in |
|
Definition
| lumbar and cervical spine |
|
|
Term
| Where are most spinal epidural abscess commonly found in |
|
Definition
|
|
Term
| What are the clinical presentation of spinal epidural abscess |
|
Definition
| Focal vertebral pain, Pain radiates along the nerve root, Spinal cord compression, Paralysis, Headache, Nuchal rigidity and focal tenderness |
|
|
Term
| What is the diag test of choice for spinal epidural abscess |
|
Definition
| MRI; Plain X-ray show osteeomyelitis |
|
|
Term
| What can cause spinal epidural abscess |
|
Definition
| Catheter, IV drug users, vertebral osteomyelitis |
|
|
Term
| What are the complications of spinal epidural abscess |
|
Definition
| endocarditis, vertebral osteomyelitis, psoas muscle abscess |
|
|
Term
|
Definition
| Proteinaceous infection particles that lack nucleic acids |
|
|
Term
| How are Prion diseases caused |
|
Definition
| transmitted by infected brain material; long incubation period |
|
|
Term
| Scrapie is assoc with what animal |
|
Definition
|
|
Term
| BSE is assoc with what animal |
|
Definition
|
|
Term
| Chronic wasting disease is assoc with what animal |
|
Definition
|
|
Term
| Transmissible mink encephalopathy is assoc with what animal |
|
Definition
|
|
Term
|
Definition
| In New Guinea; ritual cannibalism |
|
|
Term
| Clinical presentation of Kuru |
|
Definition
| Prodrome: headaches and arthralgias -- Ataxia, action tremor, involuntary movements, dementia, CN abnormalities, weakness |
|
|
Term
| Gerstmann-Strausser-Scheinker Syndrome |
|
Definition
| Midlife progressive spinocerebellar degeneration and dementia |
|
|
Term
|
Definition
| Progressive insomnia, dysautonomia (hyperhydrosis, hyperthermia, tachycardia, and hypertension), motor disturbances |
|
|
Term
| How are Familial CJD inherited |
|
Definition
|
|
Term
| What is mysterious about sCJD |
|
Definition
Unidentified virus
Spontaneous generation of a non-viral agent through cell mutation |
|
|
Term
| Clinical presentation of sCJD |
|
Definition
| P)rodrome: anxiety, sleep disturbance, weight loss -- Cognitive decline and behavioral disturbances, ataxia |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Clinical findings of vCJD |
|
Definition
Present with sensory and psychiatric disturbances, Ataxia, slurred speech, tremor, Akinetic mute state
Longer duration of disease |
|
|
Term
|
Definition
| Postmortem -- immunostaining and protein identification of tonsil biopsy |
|
|
Term
|
Definition
Young age
Methionine homozygosity at codon 129 of the PRNP gene
Residence in the UK |
|
|
Term
|
Definition
| BSE in sheep can be transmitted by blood transfusion |
|
|
Term
| How are iatrogenic CJD caused |
|
Definition
| neurosurgery, corneal grafts, dura mater grafts, and treatment with human cadaveric pituitary growth hormone and gonadotrophins |
|
|
Term
| What is the TSE guideline for ineffective sterilization and decontam. |
|
Definition
| mild detergents, chlorine dioxide, alcohols, hydrogen peroxide, aldehydes, ultraviolet irradiation |
|
|
Term
| What is the TSE guideline for effective sterilization and decontam. |
|
Definition
Autoclaving for one hour
Soaking instruments in sodium hydroxide or sodium hypochlorite for one hour |
|
|
Term
| Where do CJD affect mostly |
|
Definition
|
|
Term
| Where do vCJD affect mostly |
|
Definition
|
|
Term
| Where do Kuru affect mostly |
|
Definition
|
|
Term
| Where do Gerstmann-Sträussler-Scheinker syndrome mostly affect |
|
Definition
| Cerebellum and Spinal Cord |
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