Term
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Definition
| A decrease in the PCV, RBC count or hemoglobin values below normal values |
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Term
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Definition
| Variation in the size of cells |
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Term
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Definition
| Cessation of blood cell formation |
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Term
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Definition
| A free ruptured nucleus which has swollen so that separated chromatin can be seen |
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Term
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Definition
| Increased numbers of basophils in circulation |
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Term
| Defien basophilia in regards to staining |
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Definition
| The blue staining of a structure with a Romanowsky stain |
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Term
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Definition
| The layer of WBCs, platelets and nucleated RBCs (if present) that collects above the RBCs in sedimented or centrifuged blood |
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Term
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Definition
| DNA which makes up the nucleus of a cell |
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Term
| Define degenerative left shift |
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Definition
| The number of immature, non-segmented neutrophils exceeds the numbers of the mature, segmented neutrophils in circulation |
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Term
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Definition
| Small, irregular, blue-grey body in the cytoplasm of neutrophils made of residual RNA |
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Term
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Definition
Increased concentration of eosinophils in circulation
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Term
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Definition
| decreased concentration of eosinophils in circulation |
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Term
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Definition
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Term
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Definition
| The end product of coagulation |
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Term
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Definition
A precison instrument for manually counting cells
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Term
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Definition
| A protein found in erythrocytes; composed of heme and globin |
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Term
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Definition
| A condition in which free hemoglobin is present in the plasma |
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Term
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Definition
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Term
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Definition
| A neutrophil with six or more nuclear lobes |
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Term
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Definition
| An adjective used to describe a RBC that shows a decrease in the density of hemoglobin present in the cell, resulting in increased central pallor |
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Term
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Definition
| An adjective used to describe a RBC that shows a decrease in the density of hemoglobin present in the cell, resulting in increased central pallor |
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Term
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Definition
| Increased protein concentration in the blood |
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Term
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Definition
| Decreased protein concentration in the blood |
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Term
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Definition
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Term
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Definition
| Pyknosis and fragmentation of the nucleus |
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Term
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Definition
| irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis |
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Term
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Definition
| Neoplastic disease of the bonemarrow and blood |
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Term
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Definition
| Resembles leukemia by having a marked leukocytosis or by having a lot of immature cells in the blood; not due to neoplastic changes in the hematopoietic tissues |
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Term
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Definition
| Presence of an increased concentration of immature (non-segmented) neutrophils in circulation |
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Term
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Definition
| Increased concentration of white blood cells in circulation |
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Term
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Definition
| Decreased concentration of white blood cells in circulation |
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Term
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Definition
| Increased concentration of lymphocyes in circulation |
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Term
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Definition
| Decreased concentration of lymphocytes in circulation |
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Term
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Definition
| Decreased concentration of lymphocytes in circulation |
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Term
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Definition
| A RBC that has volume that is larger than normal |
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Term
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Definition
| A cell that is larger than normal |
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Term
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Definition
| An increased number of large RBCs |
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Term
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Definition
| A large platelet; at least as large as a normal RBC |
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Term
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Definition
| A tissue cell which has granules that contain histamine and heparin |
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Term
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Definition
| Mean corpuscular hemoglobin concentration; the average volume of the RBCs in circulation |
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Term
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Definition
| Mean corpuscular volume; the calculated average volume of the RBCs in circulation |
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Term
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Definition
| A RBC with a volume smaller than normal (adjective) |
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Term
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Definition
| An increased number of small RBCs |
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Term
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Definition
| Decreased concentration of monocytes in circulation |
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Term
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Definition
| Increased concentration of monocytes in circulation |
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Term
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Definition
| Decreased concentration of neutrophils in circulation |
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Term
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Definition
| Increased concentration of neutrophils in circulation |
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Term
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Definition
| A RBC with normal hemoglobin saturation (MCHC) |
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Term
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Definition
| A RBC with normal hemoglobin saturation (MCHC) |
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Term
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Definition
| An adjective used to describe a RBC of normal size (volume) |
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Term
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Definition
| A decrease in all blood cell (RBC, WBC, plateltes) lines |
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Term
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Definition
| The fluid component of blood |
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Term
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Definition
| Increased RBC mass (PCV; RBC count) in teh body |
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Term
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Definition
| Increased RBC mass (PCV; RBC count) in the body |
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Term
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Definition
| An increased concentration of reticulocytes in circulation |
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Term
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Definition
| Presence of an increased number of hypersegmented neutrophils in circulation |
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Term
| Define sedimentation rate |
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Definition
| The rate at which "RBCs settle in their own plasma in a given amount of time" |
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Term
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Definition
| The fluid component of the blood produced after the blood has been allowed to clot |
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Term
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Definition
| A platelet that is the size of a RBC or larger, and basophillic |
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Term
| Define shift red blood cell |
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Definition
| A RBC which is twice the size of a normal RBC and polychromatic |
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Term
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Definition
| A nucleated cell that was ruptured during smearing; due to mechanical damage or increased fragility of cell; chromatin has not spread out in distinct strands |
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Term
| Define supravital staining |
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Definition
| Use of stain that is taken up by a live cell so that "vital and functional processes" can be studied eg) New Methylene Blue or brilliant cresyl blue |
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Term
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Definition
| Decreased concentration of platelets (thrombocytes) in circulation |
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Term
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Definition
| Increased concentration of platelets (thrombocytes) in circulation |
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Term
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Definition
| A neutrophil showing certain morphological changes such as vacuolation, toxic granules, increased basophilia and or nuclear changes |
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Term
| What are Romanowsky-type stains? |
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Definition
| Composed of red (eosin) and blue (methylene blue) stain, acidic dye unites with basic parts of the cell (cytoplasm) and the basic dye unites with acidic parts of the cell (nucleic acids) |
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Term
| What stain do we use at Seneca? |
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Definition
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Term
| What is the difference between Hema 3 and Diff-Quik? |
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Definition
| only 5 one seconds dips in the fixative are required for blood smears of normal thickness |
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Term
| What are the 5 steps to staining a blood smear? |
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Definition
1) Dip the slide in the fixative for 5 one second dips, allow excess to drain
2) Dip the slide in Solution I (red) for 3-5 one second dips
3) Blot excess from end of slide
4) Dip the slide in solution II (dark blue) for 3-5 one second dips
5) Rinse with distilled water
6) Stand to dry |
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Term
| How do you adjust your blood smear technique to accomodate for thin blood? |
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Definition
| Higher angle, slower smear |
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Term
| How do you adjust your blood smear technique to accomodate for thicker blood? |
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Definition
| lower angle, faster smear |
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Term
| What is a very common cause of poor staining? What causes this? |
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Definition
Precipitated stain
Lack of thorough washing
Stain not properly filtered
Old or contaminated stain |
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Term
| What is packed cell volume and what are 2 other names for it? |
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Definition
| Proportion of whole blood composed of RBCs |
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