Term
|
Definition
|
|
Term
|
Definition
| wide spectrum antimicrobial |
|
|
Term
|
Definition
| toxicity of chloramphenicol |
|
|
Term
| drug interactions of chloramphenicol |
|
Definition
| phenytoin, tolbutamide, warfarin |
|
|
Term
| 2 yo child ingesting pills for bacterial dysentery. he had vomiting, diarrhea w/ green stools, hypothermia, hypotension, and abdominal distention. what is this drug? |
|
Definition
|
|
Term
| the mechanism of antibacterial action of tetracyclines involves |
|
Definition
| block of binding of aminoacyl-tRNA to bacterial ribosomes |
|
|
Term
| 24 yo F has syphilis and allergy to penicillin. a tetracycline will be used instead. which statement about the proposed drug treatment of this pt is accurate |
|
Definition
| for full effectiveness, tetracycline must be taken for 15 days |
|
|
Term
| clarithromycin and erythromycin have very similar spectra of antimicrobial activity. the major advantage of clarithromycin is that it |
|
Definition
| is more active against MAC |
|
|
Term
| a primary mechanism underlying the resistance of gram positive organisms to macrolide antibiotics is |
|
Definition
| methylation of binding sites on the 50S ribosomal subunit |
|
|
Term
| pt txed w/ spectinomycin for gonorrhea, did not take doxycycline comes in w/ mucopurulent cervicits. what is treatment? |
|
Definition
| treat her w/ single oral dose of azithromycin |
|
|
Term
| prophylaxis against bacterial endocarditis for someone who has prosthetic heart valves and allergic to penicillin. what is appropriate? |
|
Definition
| administer clindamycin orally 1 h before procedure |
|
|
Term
|
Definition
|
|
Term
| if pt is treated w/ erythromycin, she should |
|
Definition
| decrease her intake of caffeinated beverages |
|
|
Term
| pt should not be treated w/ telithromycin because the drug causes |
|
Definition
|
|
Term
| in a pt w/ culture positive enterococcal baceremia who has failed to respond to vancomycin b/c of resistance the tx most likely to be effective is |
|
Definition
|
|
Term
| which statement about doxycycline is accurate |
|
Definition
| it is used in lyme disease |
|
|
Term
| concerning streptogramins, which statement is accurate |
|
Definition
| they are used in the management of infections caused by multidrug-resistant streptococci |
|
|
Term
| which drug inhibits bacterial protein synthesis has a narrow spectrum of activity has been used in the management of abdominal abscess caused by b fragilis and may cause antibiotic associated colitis |
|
Definition
|
|
Term
| side effect of telithromycin |
|
Definition
| exacerbation of myasthenia gravis, hepatotoxicity |
|
|
Term
| undesirable effects of tetracyclines |
|
Definition
| photosensitivity and teeth staining |
|
|
Term
| DOC for Legionnaires' disease |
|
Definition
|
|
Term
| Drug causes teeth discoloration |
|
Definition
|
|
Term
|
Definition
| Decreases protein synthesis by inhibiting 30S ribosome |
|
|
Term
| Drug that causes gray baby syndrome and aplastic anemia |
|
Definition
|
|
Term
| Drug notorious for causing pseudomembranous colitis |
|
Definition
|
|
Term
| Oral antibiotic of choice for moderate inflammatory acne |
|
Definition
|
|
Term
|
Definition
| Inhibition of protein synthesis at the 50s subunit of ribosome |
|
|
