Term
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Definition
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|
Term
| most common wide spread mu receptor activator molecule is |
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Definition
|
|
Term
| which two acetylcholinesterase inhibitors can also inactivate plasma cholinesterase |
|
Definition
| neostigmine and pyridostigmine and physiostigmine |
|
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Term
| another name for edrophonium is |
|
Definition
|
|
Term
| what enzyme converts NE to EPI..where is it found |
|
Definition
| PNMT. Found in the brain and adrenal gland |
|
|
Term
| what is the autonomic margin of safety for any msucle relaxant |
|
Definition
| it is the difference between the amt fur relxation and the amount that causes a change in hemodynamics |
|
|
Term
| active metabolites of valium are |
|
Definition
| dethmethyldiapexepam and oxazepam |
|
|
Term
| contraindications for beta blockers are |
|
Definition
1. AV block >1 st degree
2. overt HF
3. sinus brady
4. sick sinus syndrome
5. cardiogenic shock |
|
|
Term
| what is the treatment of beta blocker toxicity? what is the mechanism of action for this drug |
|
Definition
| glucagon treats beta blocker overdose. It works by direct stimulation of adenyl cyclase which will increase cAMP intracellularly and result in increase HR. |
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|
Term
| most selective beta 1 blocker is |
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Definition
|
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Term
| which ace inhibitor is a prodrug |
|
Definition
| enalpril is a prodrug and also the only iv ace-i we have |
|
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Term
|
Definition
|
|
Term
|
Definition
| activates guanylate cyclase to increase cGMP which decreases calclium |
|
|
Term
| anthracycline is toxic to what |
|
Definition
| toxic to skeletal and cardiac muscle. Dose related fashion. Increase incident of MH |
|
|
Term
| Which chemo drug can cause severe pulmonary toxicity. due to? |
|
Definition
| Bleomycin due to superoxides not being inhibited. Maintain FiO2 < 32% |
|
|
Term
| what is mitotane used for |
|
Definition
| to treat adrenocortical tumors |
|
|
Term
| what does hydroxyurea due to our Hb |
|
Definition
| converts some Hb back to fetal Hb. |
|
|
Term
| Which chemo drug blocks tyrosine kinase and can treat CM lymphoma |
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Definition
|
|
Term
| major side effect of aminoglycosides |
|
Definition
|
|
Term
| name sx of red man syndrome |
|
Definition
1. bronchospasm
2. uritacaria
3. erythema |
|
|
Term
| which abx group inhibits p 450 |
|
Definition
|
|
Term
| which abx group has reversible inhibition of MAO |
|
Definition
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