Term
| What type of drugs will cross the placental barrier more easily? |
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Definition
| lipid-soluble, nonionized |
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Term
| Which pregnancy categories should be avoided while pregnant? |
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Definition
|
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Term
|
Definition
| agent that interferes with growth or development of the embryo or fetus and produces a permanent abnormality or death |
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Term
| In what period of fetal development are structural deformities most likely? |
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Definition
|
|
Term
| What type of detriment will a teratogen produce during the fetal period? |
|
Definition
| slowed growth or impaired organ function |
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|
Term
| How to drugs primarily enter breast milk? |
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Definition
|
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Term
| What drug class should always be avoided while breast feeding? |
|
Definition
| cytotoxic agents/ immunosuppressants |
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Term
| What act gave financial incentives for pharmaceutical companies to conduct pediatric research? |
|
Definition
| Food and Drug Administration Modernization Act (1997) |
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Term
| What two factors can affect oral absorption of drugs in children? |
|
Definition
| increased gastric pH and delayed gastric emptying |
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|
Term
| Why are IM injections avoided in pediatric patients? |
|
Definition
| unpredictable absorption rates and pain |
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|
Term
| What's the issue with administering water-soluble drugs in pediatric patients? |
|
Definition
| The proportion of water to fat is higher, which lowers the serum drug levels |
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|
Term
| What can children develop if they're given benzyl alcohol? |
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Definition
|
|
Term
| What is the preferred site for injections in infants? |
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Definition
|
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Term
| What two methods are used for calculating pediatric dosages and which one is considered more reliable? |
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Definition
| body weight method, body surface area (BSA) method ---BSA |
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|
Term
| What are the most frequent classes of drugs involving emergency department visits? |
|
Definition
| hypoglycemics, and beta blockers |
|
|
Term
| When is directly observed therapy (DOT) especially useful? |
|
Definition
| When a child is receiving long-term drug therapy |
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