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bone forming cells secrete extracellular matrix: ground substance & collagen fibers once surrounded by matrix->osteocytes |
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mature cells located in lacunae monitor and maintain bone matrix |
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large, multinucleate break down (resorb) bone release enzymes which breakdown extracellular matrix & acid which breaks down minerals |
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appears smooth and solid to naked eye composed of osteons |
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| osteon composed of this->hollow tubes inside each other |
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extracellular matrix of connective tissue-> collagen fibers and calcium phosphate |
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| give lamella ability to withstand mechanical stress |
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| harden around collagen fibers ground substance |
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channel through center of osteon contains nerves, blood, & lymphatic vessels |
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| perforating (Volkman's) canal |
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channels lying at right angles to central canal connecting vessels and nerve supply of periosteum to central canal |
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small spaces between lamella location of mature, living bone cells->osteocytes |
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hairlike canals connect all lacunae and central canal contain osteocyte extensions |
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| all osteocytes are connected by these which relay nutrients and wastes |
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honeycomb of flat and needlelike pieces->trabeculae no osteons irregularly arranged lamellae, osteocytes, canaliculi space between contains yellow bone marrow |
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compact bone surface double-layered membrane nerve fibers, blood, and lymphatic vessels enter diaphysis via nutrient foramina |
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covering superficial bone surface outer fibrous layer- dense connective tissue inner osteogenic later (cells)- osteoblasts and osteoclasts secured to underlying bone by Sharpey's fibers |
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| collagen fibers which secure periosteum to underlying bone |
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| the process by which nerve fibers, blood and lymphatic vessels enter diaphysis |
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| outer fibrous layer is composed of this type of tissue |
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| part of periosteum composed of osteoclasts and osteoblasts |
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delicate membrane covering internal surfaces of bone lines medullary cavity and membrane contains osteoblasts and osteoclasts |
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| soft tissue that fills the hollow space of some bones |
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active bone marrow contains stem cells that will develop into different types of blood cells location- spongy bone of epiphysis in long bones and flat bones(adults) |
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inactive bone marrow contains adipoctyes location-medullary cavities(adults) |
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| osseus connective tissue formation |
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| formation of bony skeleton occurs in ________ |
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| infancy through adolescence |
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| bone growth occurs during this period |
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| bone remodeling and repair occurs when? |
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| intramembraneous ossification |
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Definition
bone formation from dense (fibrous) connective tissue formation of flat bones |
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| endochondrial ossification |
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Definition
bone formation from hyaline cartilage connective tissue formation of long, short, and irregular bones |
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| cells of cartilage which trigger calcification |
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| chondrocytes enlarge and trigger deposition of calcium from blood vessels |
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| bone formation from dense(fibrous) CT |
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| where does intramembranous ossification occur? |
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| which bones develop by intramembranous ossification? |
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| during which period(s) of human life cycle does intramembranous ossification occur? |
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| bone formation from hyaline cartilage |
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| where does endochondral ossification occur? |
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| long bones, short bones, irregular bones |
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| which bones develop by endochondral ossification? |
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| during which period(s) of human life cycle does endochondral ossification occur? |
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| hormones (growth hormones, sex hormones, thyroid hormones) |
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| what controls lengthwise bone growth? |
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| from infancy through adolescence |
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Definition
| during which period(s) of human life cycle does lengthwise bone growth occur? |
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| from infancy through adolescence |
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| during which period(s) of human life cycle does diametric bone growth occur? |
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| produced by parathyroid glands |
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hyaline cartilage connective tissue plate separates diaphysis and epiphysis |
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composed of hyaline cartilage connective tissue covers joint surface of each epiphysis |
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| addition of new bone by osteoblasts |
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| removal of bone by osteoclasts |
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-occurs where bone is injured, extra strength is required(areas of mechanical stress) or to replace bone that has been resorbed -osteoblasts produce extracellular matrix -crystals of calcium and phosphate form around collagen fiber of matrix |
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-surface of osteoclast is in direct contact w/ bone surface -secretes enzymes breaking down extracellular matrix -secrete acid which dissolves calcium and phosphate crystals and converts to soluble form (enter bloodstream) |
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support protection movement mineral storage blood cell formation |
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| five functions of skeletal system |
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meniscus of knee intervertebral disc pubic symphysis |
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| hyaline articular cartilage |
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articular cartilage costal cartilage nasal cartilage |
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| produced by the thyroid gland |
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| secretes ground substance and collagen fibers |
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