Term
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Definition
| the process by which a substance moves into the bloodstream from the site where it was administered |
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Definition
| is a severe sick effect such as shock or death |
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Definition
| drug that when taken with another drug so the two can work together |
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Term
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Definition
| drugs do the opposite by rendering another drug less powerful |
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Term
| biotrasnformation/metabolism |
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Definition
| how our body breaks the medication down into usable components and waste products |
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Term
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Definition
| second phase of drug cycle: which is the delivery of a drug to the appropriate site after the drug has been absorbed into the bloodstream. |
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Term
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Definition
| ensures that waste products are removed and do not build up on the body (called cumulation) |
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Term
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Definition
| legnth of time required for its concentraion of a drug to decrease by one-half in the blood plasma and therefore affects the duration of potency for a medication |
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Term
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Definition
| a uniquereaction of a drug |
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Term
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Definition
| the study of metabolism and action of drugs |
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Term
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Definition
| sites where the medication binds to create a physiological effect |
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Term
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Definition
| usually mild, effects of medicaion |
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Term
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Definition
| when a drug is more powerful than when each drug is taken separately |
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Definition
| interferes with normal fetal development |
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Term
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Definition
| poisonous from too much medication |
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Term
| enterally, parenterally, percutaneously |
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Definition
| 3 ways a drug can be administered |
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Term
| directly into GI system: orally, rectally, tube into system |
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Definition
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Term
| IM, IB, subcu, intradermal injections |
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Definition
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Term
| inhalation, sublingual, topical, transdermal |
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Definition
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Term
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Definition
| fastest way to blood supply |
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Term
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Definition
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Term
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Definition
| what can hinder possible absoroption? |
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Term
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Definition
| how much of the drug is absorbed for use |
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Term
1. fat/lipid solubility
2. pH
3. concentration of the medicaion
4. length of contact
5. Age
6. Food
7. Depth of breathing |
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Definition
| what are the SEVEN factors that can effect the absorption rate |
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Term
1. blood-placental
2. blood-brain
3. blood-testicular |
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Definition
| Name the 3 barriers that can prohibit medication from passing through them |
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Term
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Definition
| what type of drug does NOT cross the blood-placental barrier? |
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Term
1. blood-bran barrier
2. blood-testicular |
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Definition
| Many psychotropic drugs have negative sexual effects because they cross what two barriers? |
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Term
| The liver, kidney, and intestines |
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Definition
| 3 parts of the body that metabolize drugs |
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Term
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Definition
| a drug administered in its inactive form to become activated through metabolism (bc the metabolite is the desired treatment) |
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Term
| fosamprenavir (Lexiva) used in the fight against HIV |
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Definition
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Term
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Definition
| where excretion mainly occurs |
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Term
| bile, gas by lungs, saliva, sweat glands, and breast milk |
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Definition
| Name 5 ways drugs can be excreted |
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Term
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Definition
| point at which the drug has the maximum desired effect |
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Term
| gentamicin (antibiotic that is nephrotoxic and ototoxic |
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Definition
| name a drug that needs to be monitored for toxicity |
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Definition
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Definition
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Definition
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Term
| Tylenol with codeine (used for pain relief, and to diminish cough reflex) |
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Definition
| EX of synergistic medicine |
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Term
| antibiotics (makes BC less effective) |
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Definition
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Term
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Definition
| tetracycline because ineffective if taken with what drug? |
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Term
| Flexeril (cyclobenzaprine)- muscle relxatant |
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Definition
| what medication causes dizziness and drowsiness along with its intended action? |
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Term
| Jaundice (yellowing of the skin and eye) |
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Definition
| undetected liver damage can show what s/s? |
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Term
| alcohol, acetaminophen, isoniazid, and aspirin |
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Definition
| 4 drugs that can cause liver damage |
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Term
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Definition
| taking these long term can cause ulcers |
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Term
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Definition
| what drug can be given to prevent the side effect of ulcers? |
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Term
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Definition
| What should patients cease in order to prevent ulcers? |
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Term
| non steroidal anti-inflammatory (ibuprofen) |
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Definition
| these medications can cause damage to the kidney |
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Term
| BUN (blood urea nitrogen) |
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Definition
| Test to determine kidney function |
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Term
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Definition
| Oxygen can be very damaging to the ___ |
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Term
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Definition
| these drugs are toxic to bone marrow |
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Term
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Definition
| Patients on this med should be monitored for bleeding, dark tarry stools |
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Term
| united states pharmacopoeial national formulary |
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Definition
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Term
| united states pharacopoeial/ dispensing information |
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Definition
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