Term
| Dihydrofolate is reduced by what to tetrahydrofolate |
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Definition
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|
Term
| Inhibits dihydrofolate reductase |
|
Definition
| Trimethoprim, Methotrexate, Pyrimethamine |
|
|
Term
| Inhibits dihydropteroate synthase |
|
Definition
|
|
Term
|
Definition
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|
Term
|
Definition
|
|
Term
| Sulfamethoxazole/trimethoprim TX |
|
Definition
| P. carinii, UTI, shigella, diarrhead, granuloma inguinale, acute otitis media |
|
|
Term
|
Definition
| SJ syndrome, Kernicterus newbornes, aplastic anemia, hepatic failure |
|
|
Term
| Why do sulfa drugs cause kernicterus in babies? |
|
Definition
| compete with bilirubin for binding sites on albumin |
|
|
Term
|
Definition
| Leprosy, P. carinii, dermatitis hepetiformis |
|
|
Term
|
Definition
| Hemolytic Anemia (g6PD), methemoglobinemia, pancreatitis, hepatitis, neuropathy |
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|
Term
|
Definition
| UTI and in combination with sulfamethoxazole |
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|
Term
|
Definition
| inhibits bacterial DHFR preventing tetrahydrofolate production |
|
|
Term
|
Definition
| SJ syndrome, leukopenia, rash, itching |
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|
Term
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Cancer, leukemia, AI diseases, ectopic pregnancy |
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|
Term
|
Definition
| Toxic to GI, Bone Marrow, toxic to fetus, a lot of bad shit |
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