Term
| Who came up with the Vaccine Information Pamphlets (VIN)? |
|
Definition
|
|
Term
| what are the 10 specific points regarding vaccination? |
|
Definition
| frequency, severity, and potential long term-effects 2. symptoms or reactions 3. precautionary measures 4. early warning signs and symptoms 5. monitering adverse affects 6. how to report adverse reactions 7 contraindications 8. ID high risk groups 9. federal recomendation 10. Other relevand info. |
|
|
Term
| What program are VIPs associated with? |
|
Definition
| National vaccine injury compensation program |
|
|
Term
| What 3 things did parents want to know about before giving their children vaccination? |
|
Definition
| side effects, purpose of vaccine, safety/risk of vaccination, (contraindications to vaccination) |
|
|
Term
| What viral group and genous does the measles virus belong? |
|
Definition
| paramyxovirus group and morbillivirus genus |
|
|
Term
| what size and shape is the measles virus? |
|
Definition
| large w/ pleomorphic and spherical shape |
|
|
Term
| What are the 2 major components of the measles virus? |
|
Definition
outer lipoprotein envelope, and
Internal helical nucleocapsid made of RNA and proteins. |
|
|
Term
| Is the measles a RNA (+) or (-) virus? |
|
Definition
|
|
Term
| How does the Measles virus replicate? |
|
Definition
| RNA-dependent RNA-polymerase |
|
|
Term
| What is the name of the major strain of Measles virus that we use in vaccinations ? |
|
Definition
|
|
Term
| How many structural proteins does the Edmonston strain encode for? |
|
Definition
|
|
Term
| What are the 3 proteins that are made to have a reaction against in the measles virus and where do they come from? |
|
Definition
| (H) hemagglutinin
(F) fusion
(M) generation of new viral particals |
|
|
Term
| What are the 3 symptoms of a Measles infection? |
|
Definition
| acute, febrile, and exanthematous illness |
|
|
Term
| Where is the primary site of infection of Measles? |
|
Definition
| epithelium of nasopharynx |
|
|
Term
| How does the Measles virus transmission occur? |
|
Definition
|
|
Term
| Where does measles grow in the body? |
|
Definition
| in the epithelium and lymphatic tissue of the upper respiratory tract |
|
|
Term
| What are the 2 phases of the measles virus infection? |
|
Definition
MULITPLICATE- virues goes to various lympoid tissue
PROTROMAL - symptomatic in the throat then at the end of prodromal stage you get the rash |
|
|
Term
| How long is the incubation period for measles? |
|
Definition
|
|
Term
| What are the prodromal symptoms of measles? |
|
Definition
| coryza, conjunctivits, dry cough sore throad, HA, low fever, koplik spots (blue-white spod on a red background) |
|
|
Term
| what happens at the end of the prodromal stage of Measles? |
|
Definition
| maculopapular rash appears then becomes confluent then disapears over 5-7 days |
|
|
Term
| From where is the virus given off durring an infection? |
|
Definition
| from any secretions, respiratory, tears, urine and can be before any symptoms occur |
|
|
Term
| What is the most common way to diagnose measles? |
|
Definition
| immunoassays that are commercially available |
|
|
Term
| what is the current measles vaccine in the US? |
|
Definition
| Moraten - live ateenuated |
|
|
Term
| how is the Measles vaccine given (other then in a shot)? |
|
Definition
| trivalent with mumps and rubella |
|
|
Term
| What are three other strains used in other countries for measles? |
|
Definition
Russia - leningrad 16
China - shanghi 191
Japan - CAM 70 |
|
|
Term
| What determines the efficacy of the measles vaccine? |
|
Definition
| decrease in incidence of the disease |
|
|
Term
| Who came up with the idea to irridacate these childhood diseases? |
|
Definition
|
|
Term
| do the majoryity of people going to school have the measles vaccine |
|
Definition
|
|
Term
| Are the majority of the people who have the measles vaccine actually protected by it? |
|
Definition
|
|
Term
| have their been vaccination failure? |
|
Definition
|
|
Term
| What are the 2 major causes of vaccination failures? |
|
Definition
PRIMARY- lack of seroconversion (don't make an immune response)
SECONDARY - loss of immunity after seroconversion |
|
|
Term
| Which type of vaccination failure is the most common? |
|
Definition
| primary - 5%, Secondary = should be negliable |
|
|
Term
| Although the CDC didn't manage to irradicate measles totally what did they manage to do? |
|
Definition
|
|
Term
| Why does the CDC think that there were outbreaks in areas that were highy vaccinated? |
|
Definition
that the measles virus is so contagious that they need higher efficacy of vaccine than they thought
(or secondary measles vaccine failure) |
|
|
Term
| what is the mean age of a person with measles? |
|
Definition
|
|
Term
| What does an outbreak of measles in a school test the theory of? |
|
Definition
|
|
Term
| What do they think increased the contact rate of measles? |
|
Definition
| the fact that it is airborne |
|
|
Term
| what does an increased contact rate of a disease mean to the vaccine? |
|
Definition
| that it requires more people to have it than previously calculated to give herd immunity |
|
|
Term
| What may also be a factor in the introduction of a disease like measles? |
|
Definition
| socioeconomics, disease may be introduced from poor nutrition and decreased hygiene |
|
|
Term
| Where is the only place that high mortality rates are seen with measles? |
|
Definition
|
|
