Term
|
Definition
| spheroplast --> protoplast |
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|
Term
| Separates dividing daughter cells, anchor flagella, some components contribute to virulence |
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Definition
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|
Term
| made up of cytoplasmic membrane and peptidoglycan |
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Definition
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|
Term
| made of phospholipids and protein |
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Definition
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|
Term
| Lipoteichoic Acid, Linear polymers of alternating substances |
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Definition
|
|
Term
|
Definition
| cross-link the strands of polysaccharides |
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Term
|
Definition
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|
Term
| the cells are often already dead from the antibiotic but the LPS can react with your immune system |
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Definition
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|
Term
| Analogs of D-Ala-D-Ala (di-alamine peptide) |
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Definition
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|
Term
| lactam + PBP (-NH2 or -OH) |
|
Definition
| inhibit cell wall synthesis of bacteria |
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|
Term
| lactam + endogenous protein (host) |
|
Definition
| hypersensitivity reaction |
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|
Term
|
Definition
| neither will remain active |
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|
Term
| Lactam opens spontaneously |
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Definition
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|
Term
|
Definition
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|
Term
| Major mode of evolution of beta-lactam resistance |
|
Definition
| PBPs with Beta-lactamase activity only (penicillinases, cephalosporinases, mixed) |
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|
Term
| competitive, irreversible (suicide) inhibitors |
|
Definition
| beta-lactamase inhibitors |
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|
Term
| Anaphalaxis most serious (0.01%) hypersensitivity reactions |
|
Definition
| immediate onset (<30 min) |
|
|
Term
| accelerated reactions (rash, fever) |
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Definition
|
|
Term
| delayed reactions (skin reactions, nephritis, serum sickness) |
|
Definition
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|
Term
| nonurticarial maculopapular rash; not immune-mediated |
|
Definition
| ampicillin rash (also amoxicillin) |
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|
Term
|
Definition
| serendipitous discovery by Fleming |
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|
Term
|
Definition
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|
Term
|
Definition
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|
Term
| Precursor of semisynthetic penicillins |
|
Definition
|
|
Term
| nucleus is 7-aminocephalosporanic acid |
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Definition
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|
Term
| greater seizure potential, not used in meningitis |
|
Definition
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|
Term
| Sensitivity similar to cefotaxime and ceftazidime |
|
Definition
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|
Term
| rather large size, therefore cannot get through the gram negative outer cell membrane and can only be used for gram positive |
|
Definition
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|
Term
| systemic effects of Vancomycin |
|
Definition
| Ototoxicity and nephrotoxicity |
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|
Term
|
Definition
| stimulation of histamine release during or within 10 min after IV infusion; pretreat with histamine 1 blocker and infuse slowly |
|
|
Term
| produced by licheniformis B. subtilis |
|
Definition
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|
Term
| Highly nephrotoxic (never used for systemic gram positive infection) |
|
Definition
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