Term
| Key Features of Cartliage and Bone |
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Definition
| support, connect and protect other tissues and organs |
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Term
| What are the components of cartliage |
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Definition
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Term
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Definition
immature cell
capable of division and matrix production |
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Term
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Definition
do not divide
maintain matrix |
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Term
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Definition
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Term
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Definition
found along outer surfaces (periphery) of cartliage
divide and product matryce
important for repair of injury |
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Term
| What type of fibers make up cartilage matrix |
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Definition
Type II collagen
(special cases: elastic fibers) |
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Term
1)Cartilage ground substance is made up of
2)Ground Substance Functions |
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Definition
glycoaminoglycans (form proteoglycans)
hyaluronic acid
Fucntions: matrix stability, volume definitions, and compressive properties |
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Term
| Location of Hyaline Cartilage |
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Definition
| bone forming sites in young animals, respiratory airways, supporting sturctures of laynx and nose |
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Term
Cells of Hyaline Cartilage
What are their histological appearance |
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Definition
chrondocytes formed from chondroblasts
clear "halos" lacunae
cells divide and form "cell nests" |
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Term
1)Matrix components of Hyaline Cartilage
2)Matrix organization |
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Definition
collagen fibers
dense regular CT not readily visible
Territorial- more basophilic surounging lacunae
Interterritorial- less basophilic "everything else" |
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Term
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Definition
| seperates and binds to cartliage to surrounding non-collagenous tissue |
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Term
Elastic Catilage
(Location, Cell, Matrix) |
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Definition
-external ear, external auditory canal, auditory tube, epiglottis
-Chondrocytes
-idential fo hylane except visible elastic fibers (bright pink by H&E) |
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Term
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Definition
Hyaline Cartilage
Elastic Cartilage
Fibrocartilage |
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Term
Fibrocartilage
(location, cell, matrix) |
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Definition
-intervertebral discs, ligaments/tendon attachments, joint menisci , pubic symphysis (regions of transition fibrous/hyaline cartliage)
- orderly fashion of large bundles of collageous fibers
-ALWAYS LOOK FOR LACUNAE
-NO PERICHONDRIUM |
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Term
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Definition
| chrondroblasts divide and secrete matrix |
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Term
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Definition
| growth along edges of outer boundary of cartliage |
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Term
|
Definition
Compact Bone
Spongy Bone
Woven Bone |
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Term
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Definition
-capable of dividing
-organice matrix secretion, mineralization |
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Term
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Definition
-derived from osteoblast
-completely embedded in matrix
- contact with other osteocytes/blasts through canaliculi |
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Term
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Definition
-multinucleated giant cells
-derived from monocytes/macrophages
-break down mineralized (inorganic) matrix
-degradative activity at brush border |
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Term
| What is a unquie feature of matrix of bone |
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Definition
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Term
1)What Fibers make up Bone?
2)Purpose |
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Definition
Type I Collagen
Give TENSILE STRENGTH |
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Term
| Components of Lamellar bone |
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Definition
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Term
Components of
Osteon (Haversian system) |
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Definition
-central canal (Haversian canal)
-lamellae
-osteocytes
-lacunae
-canaliculi
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Term
| central canal (Haversian canal) |
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Definition
center of osteon
contains blood vessels
lining cells call endosteum |
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Term
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Definition
| concentric layers of bony matrix |
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Term
|
Definition
| small sapces around osteocyte |
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Term
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Definition
connect adjacent lacunae
cell-cell contact b/t osteocytes |
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Term
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Definition
| canals interconnecting long central canals and osteons |
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Term
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Definition
| layered fragement with degraded osteons and no central canal |
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Term
| inner circumferential lamellae |
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Definition
| layers of compact bone on inner surface arranged in a circular pattern around inner cavity on bone |
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Term
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Definition
| layer of osteoblasts covering of inner surface of compact bone |
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Term
| outer circumferential lamellae |
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Definition
| layers of compact bone on outer surface arranged in a circular pattern around outer cavity on bone |
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Term
Periosteum
what are the layers |
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Definition
covering of outer later of compact bone
-highly vasculiar and innervated
1)Fibrous Layer (fibroblast)
2) Osteogenic later (highly cellulared, filled w/ osteblasts) |
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Term
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Definition
more interosseus spce
bony trabeculae= complex lattice work of bone providing strength
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Term
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Definition
immature bone (ossification centers of fetus)
outer circumferencial lamellae (adults)
ALWAYS REPLACED BY LAMELLAR BONE |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
| By transformation of existing CT |
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Term
| Intramembranous Ossification |
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Definition
- replacement of loose CT
- found in woven bone and appositional growth (edges of bone) |
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Term
| Endochondral (intracartilagenous) Ossification |
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Definition
| replacement of preformed hylaine cartilage by appositional and interstitial growth |
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Term
| Primary Center of Ossification |
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Definition
develops as the perichondrium , process of calcification, calcification of matri retards diffusion of nutrients so cells die
- CALCIFIED CARTILAGE IS THEN REPLACED WITH BOONE (CARTILAGE DOES NOT BECOME BONE) |
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Term
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Definition
| all centers of ossification that develop after the primary |
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Term
|
Definition
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Term
| Steps in Bone Growth in Epiphyseal Cartilage |
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Definition
1) Zone of Resting Cartilage (cells do not divide)
2) Zone of Proliferation (stacks of wedge-shaped actively dividing cells)
3) Zone of Maturation (columns of maturing chondrocytes, hypertrophy)
4) Zone of Calcification (narrow ridge of large cells with thin intercellular matrix, stains very basophili)
5) Zone of Ossification (ossified matrix partially eroded) |
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Term
| Bone Growth in Metaphysis |
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Definition
1) primary spongiosa: calcified cartilage, woven bone, and lamellar bone
2) Secondary Sponiosa: lamellar bone ONLY |
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Term
| Mechanisms for Increasing Diameter |
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Definition
| Increases by simple appositional growth, as diaphysis diameter increases so does marrow cavity |
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Term
| Synovial Joints (components) |
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Definition
Articular Cartilage
Subchondral Bone
Joint Capsule |
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Term
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Definition
No periosteum
Three layered zones (superficial, intermediate, and deep)
Tide Line |
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Term
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Definition
| Transitional between non-mineralized and mineralized matrix |
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Term
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Definition
| underlying compact bone of epiphysis |
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Term
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Definition
synovial layer: secretes synovial fluid
fibrous layer: adds stability |
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Term
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Definition
within medullary cavity
1) red bone marrow: hematopoietic
2) yellow bone marrow: adipose tissue |
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