Term
|
Definition
| inhibits Na/K ATPase -> inc intracell Ca |
|
|
Term
|
Definition
|
|
Term
| digitoxin cholinergic toxicity |
|
Definition
| N/V, blurry yellow vision, diarrhea |
|
|
Term
|
Definition
| inc PR, dec QT, scooping T wave inversion, arrhythmia, hyperkalemia |
|
|
Term
| digoxin toxicity worsened by |
|
Definition
| renal failure, hypokalemia, quinidine |
|
|
Term
|
Definition
| normalize K, lidocain, (atropine if bradycardic) anti-dig, Mg |
|
|
Term
|
Definition
|
|
Term
|
Definition
| acute decompensated heart failure |
|
|
Term
|
Definition
|
|
Term
|
Definition
| qunidine, procainamide, disopyramide |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Class IA, sotalol, ibutilide |
|
|
Term
|
Definition
| lidocaine, mexiletine, tocainide |
|
|
Term
|
Definition
|
|
Term
| acute ventricular arrhythmias |
|
Definition
|
|
Term
| SE: CNS stimulation/depression |
|
Definition
|
|
Term
|
Definition
|
|
Term
| intractable SVT and Vtachs that progress to Vfib |
|
Definition
|
|
Term
| SE: proarrhythmic esp post-MI |
|
Definition
|
|
Term
| class of antiarrhytmics effected by hyperkalemia |
|
Definition
|
|
Term
|
Definition
| propranolol, esmolol, metoprolol, atenolol, timolol |
|
|
Term
|
Definition
| dec cAMP, and Ca; dec slope of phase 4 at AV node |
|
|
Term
| slowing ventricular rate in Afib |
|
Definition
|
|
Term
|
Definition
| impotence, exacerbation of asthma, bradycardia, AV block, CHF, sedation, sleep alterations, mask hypoglycemia |
|
|
Term
|
Definition
|
|
Term
|
Definition
| ibutilide, sotlol, bretylium, amiodarone, dofetilide |
|
|
Term
|
Definition
|
|
Term
|
Definition
| pulmonary fibrosis, hepatotoxic, hyper/hypothyroid, corneal deposits, blue/grey skin, photo dermatitis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| used for prevention of nodal arrhythmias |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| diagnosing/abolishing SVT |
|
|
Term
|
Definition
|
|
Term
| used for torsades and dig toxicity |
|
Definition
|
|
Term
|
Definition
| diuretics, ACEI, ARB, CCB |
|
|
Term
|
Definition
| diuretic, ACEI, ARB, beta blocker, spironolactone |
|
|
Term
|
Definition
| ACEI, ARB, CCB, diuretics, Beta blockers, alpha blockers |
|
|
Term
|
Definition
| inc cGMP -> smooth mm relax of arterioles -> dec afterload |
|
|
Term
| hydralazine clinical uses |
|
Definition
| HTN crisis, CHF, hypertension in pregnancy |
|
|
Term
| what is hydrazine coadministered with? |
|
Definition
| beta blocker to prevent reflex tach |
|
|
Term
|
Definition
| compensatory tachy; fluid retention, nausea, HA, angina, lupus-like |
|
|
Term
| dihydropyridine CCB names |
|
Definition
|
|
Term
| nondihydropyridine CCB names |
|
Definition
|
|
Term
| CCB on vascular smooth mm |
|
Definition
| nifedipine > diltiazem > verapamil |
|
|
Term
|
Definition
| verapamil > diltiazem > nifedipine |
|
|
Term
|
Definition
| HTN, angina, arrhythmias, rinzmetal's raynauds |
|
|
Term
|
Definition
| cardiac depression, AV block, peripheral edema, flushing, dizziness, constipation |
|
|
Term
|
Definition
| inc cGMP via direct release of NO; can cause CN toxicity |
|
|
Term
|
Definition
| D1 agonist, relaxes renal vascular smooth mm |
|
|
Term
|
Definition
| K channel open -> hyper polarize and relaxes vascular smooth mm; can cause hyperglycemia |
|
|
Term
|
Definition
| vasoculate by inc cGMP -> more in veins -> dec preload |
|
|
Term
|
Definition
|
|
Term
|
Definition
| reflex tachy, hypotension, flushing, HA, "monday disease" |
|
|
Term
|
Definition
| K efflux -> hyperpolarization -> dec TPR |
|
|
Term
|
Definition
| pericardial effusion, hypetrichosis, salt and water retention |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| nitrates effect on: contractility |
|
Definition
|
|
Term
|
Definition
|
|
Term
| nitrates effect on: ejection time |
|
Definition
|
|
Term
|
Definition
|
|
Term
| beta blocker effect on: EDV |
|
Definition
|
|
Term
| beta blocker effect on: BP |
|
Definition
|
|
Term
| beta blocker effect on: contractility |
|
Definition
|
|
Term
| beta blocker effect on: HR |
|
Definition
|
|
Term
| beta blocker effect on: ejection time |
|
Definition
|
|
Term
| beta blocker effect on: MVO2 |
|
Definition
|
|
Term
| nitrates + beta-blocker effect on: EDV |
|
Definition
|
|
Term
| nitrates + beta-blocker effect on: BP |
|
Definition
|
|
Term
| nitrates + beta-blocker effect on: contractility |
|
Definition
|
|
Term
| nitrates + beta-blocker effect on: HR |
|
Definition
|
|
Term
| nitrates + beta-blocker effect on: ejection time |
|
Definition
|
|
Term
| nitrates + beta-blocker effect on: MVO2 |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| SE: hepatotoxic and rhabomyolysis |
|
Definition
|
|
Term
| red, flush face with what drug? how prevented? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| SE: cholesterol gallstones |
|
Definition
| bile acid binding resins, vibrates |
|
|
Term
|
Definition
| inhibit HMG-CoA reductase |
|
|
Term
|
Definition
| inhibits lipolysis in adipose tissue; reduces heptic VLDL secretion |
|
|
Term
|
Definition
| prevent intestinal reabsorption of bile acids |
|
|
Term
|
Definition
| prevent cholesterol reabsorption at small intestine brush border |
|
|
Term
|
Definition
| upregulate LPL via PPAR-alpha |
|
|
Term
| ezetimibe effects on cholesterol |
|
Definition
|
|
Term
| statin effects on cholest |
|
Definition
|
|
Term
| niacin effects on cholesterol |
|
Definition
|
|
Term
| BABR effect on cholesterol |
|
Definition
dec LDL
slightly inc HDL and trig |
|
|
Term
| fibrates effect on cholesterol |
|
Definition
|
|
