Term
| Esophagus, stomach, colon cancer |
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Definition
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Term
| Mesothelioma, bronchogenic carcinoma |
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Definition
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|
Term
| Transitional cell carcinoma of bladder |
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Definition
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|
Term
| Squamous cell carcinoma, liver angiosarcoma |
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Definition
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|
Term
| Hodgkin's lymphoma, nasopharyngeal carcinoma, oral hairy leukoplakia |
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Definition
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Term
| Cervical, penile, vulvar, anal |
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Definition
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Term
|
Definition
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Term
|
Definition
| Forms a complex between DNA and topoisomerase II |
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Term
|
Definition
Alkylates DNA
Toxicity > pulmonary fibrosis |
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Term
|
Definition
Fragments DNA
Toxicity > pulmonary fibrosis |
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Term
|
Definition
Blocks purine synthesis
Metabolized by xanthine oxidase |
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Term
|
Definition
Cross-links DNA
Nephrotoxic and ototoxic |
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Term
|
Definition
Nitrogen mustard
Alkylates DNA (eletrophil that binds DNA) |
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Term
|
Definition
| Folic acid analog that inhibits dihydrofolate reductase |
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Term
|
Definition
| Prevents tubulin dissasembly |
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|
Term
|
Definition
Intercalates DNA
Produces oxygen free radicals
Cardiotoxic |
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Term
|
Definition
| DBA alkylating agents used in brain cancer |
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Term
|
Definition
| Prevents tubulin assembly |
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Term
|
Definition
Inhibits thymidylate synthase
Decreased nucleotide synthesis |
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Term
|
Definition
SERM
Blocks estrogen binding to ER(+) cells |
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Term
|
Definition
| Mechanism similar to antivirals acyclovir and foscarnet |
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|
Term
|
Definition
| Mechanism similar to fluoroquinolones |
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Term
|
Definition
| Mechanism similar to trimethoprim |
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Term
|
Definition
| Monoclonal antibody against HER-2 |
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Term
|
Definition
| Free radical-induced DNA breakage |
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|
Term
|
Definition
| Inhibitor of PRPP synthetase |
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Term
|
Definition
| Reversible with leucovorin |
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|
Term
| Vincristine/vinblastine, methotrexate |
|
Definition
| Treatment for choriocarcinoma |
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Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
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|
Term
| Cisplatin, bleomycin, etoposide |
|
Definition
| Treatment for testicular cancer |
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Term
|
Definition
| Applied topical for AKs and basal cell carcinoma |
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Term
|
Definition
| Treatment for childhood tumors |
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Term
|
Definition
| Inhibits ribonucleotide reductase |
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|
Term
|
Definition
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|
Term
|
Definition
| Antibody against Philadelphia chromosome |
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|
Term
|
Definition
| Most common malignant primary bone tumor of children |
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|
Term
|
Definition
| Most common malignant primary bone tumor in adults |
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Term
|
Definition
| Pruritic, purple, polygonal papules |
|
|
Term
| Pemphigus vulgaris, Stevens-Johnson syndrome |
|
Definition
| Life threatening rash w/bulla |
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|
Term
|
Definition
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|
Term
|
Definition
| Pruritic vesicles a/w celiac disease |
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|
Term
|
Definition
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|
Term
|
Definition
| Thickened scar especially around face and neck |
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Term
|
Definition
| Antibodies against epidermal basement membrane |
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|
Term
|
Definition
| Antibodies against epidermal cell surface |
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Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
Sand-paper
Predisposition to squamous cell carcinoma |
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|
Term
|
Definition
| Skin rash and proximal muscle weakness |
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|
Term
|
Definition
| Honey crusting lesions common about the nose and lips |
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|
Term
|
Definition
| Hyperkeratosis and koilocytosis |
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|
Term
|
Definition
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