Term
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Definition
| 4.5-5.5 compared to H20=1 |
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Term
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Definition
| 38 degrees C or 100.4 degrees F |
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Term
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Definition
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Term
| NaCL% Concentration of Blood |
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Definition
| 0.80%= physiological saline |
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Term
| Blood's % compared to body weight |
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Definition
| Approximately 8%, 5-6 Lier or 1.5 gallons |
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Term
| Function of Blood Transport |
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Definition
| O2, CO2, nutrients, wastes, hormones, heat |
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Term
| Function of Blood Regulation |
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Definition
| regulates pH, body temperature, H2O contents of cells (all bodily fluids are derived from the blood) |
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Term
| Preventative Function of Blood |
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Definition
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Term
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Definition
| Combat toxins and microbes (foreign invaders) via WBC's and their chemical interactions |
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Term
| Defensive proteins produced by B-Lymphocytes |
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Definition
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Term
| Series of defensive plasma proteins produced by the liver |
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Definition
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Term
| A liquid connective tissue |
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Definition
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Term
| Defensive proteins produced by T-Lymphocytes |
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Definition
Interferon
Interleukin I and II |
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Term
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Definition
Formed Elements:
RBC's WBC's Platelets |
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Term
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Definition
| Plasma--> 91.5% is H2) and 8.5% is Solutes--> 7% of Solutes is Proteins and 1.5% is Other Solutes. |
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Term
| 7% of Proteins in the Solutes of Plasma is made up of what 3 proteins? |
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Definition
Albumin (Osmolarity- controls what comes in and out of the blood)
Globulins (antibodies)
Clotting Proteins |
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Term
| Erythrocytes (RBC) physical traits |
|
Definition
Biconcave Discs
No Nuclei
Contain Hemoglobin
Red Pigmented b/c of hemoglobin
4 Strands of globin protein (alpha1, alpha2, beta1, beta2)
Heme=Fe++ and pigment proteins:
in arteries:oxyhemoglobin(binds O2 molecules
in veins: carbaminohemoglobin (binds CO2) |
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Term
| Why are arteries more red? |
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Definition
| Because oxyhemoglobin binds O2 molecules |
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Term
|
Definition
| Carbaminohemoglobin binds CO2 and there is less oxygen |
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Term
| Life Span of an Erythrocyte (RBC) |
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Definition
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Term
| Amount of Erythrocytes in Male and Female |
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Definition
Males: ~5.4mil/mm3
Females: ~4.8mil/mm3 |
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Term
| The rate of Erythropoiesis is controlled by |
|
Definition
| O2 level and kidney hormone erythropoietin; negative feedback loop |
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Term
| Erythropoiesis is monitored via... |
|
Definition
reticulocyte count
-checks rate of RBC production
-used to diagnosis anemia |
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Term
| stomach/digestive tract produces intrinsic factor that is required to absorb the B12 used in the production of RBCs, used by bone marrow. |
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Definition
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Term
| The ratio of red blood cells compared to the total volume of blood |
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Definition
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|
Term
| Hematocrit of males and females |
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Definition
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Term
|
Definition
-Neutrophil
-Eosinophil
-Basophil |
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|
Term
| Nucleus multilobed; inconspicuous cytoplasmic granules |
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Definition
|
|
Term
| Nucleus bilobed; red cytoplasmic granules |
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Definition
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Term
| Nucleus bilobed; large purplish-black cytoplasmic granules |
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Definition
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Term
| Function: Phagocytize bacteria |
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Definition
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Term
| Function: Kill parasitic worms; complex role in allergy and asthma |
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Definition
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Term
| Function: Release histamine and other mediators of inflammation; contain heparin, an anticoagulant |
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Definition
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Term
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Definition
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
|
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Term
| Amount of WBC (Leukocytes) |
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Definition
|
|
Term
| General Function of Leukocytes (WBC) |
|
Definition
| to combat infection and foreign invasion by toxins, foreign cells, bacteria, viruses, fungi. |
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Term
| Two Types of Agranular WBC's (Leukocytes) |
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Definition
| Lymphocytes and Monocytes |
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Term
| -Lymphoid tissue-production (primarily thymus) |
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Definition
|
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Term
|
Definition
| produce antibodies or T-Cells |
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Term
| How much of total WBC count does Lymphocytes make up? |
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Definition
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Term
|
Definition
B- bone marrow derived
T- Thymus derived |
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Term
| How much of total WBC Count does Monocytes make up? |
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Definition
|
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Term
|
Definition
| Phagocytize foreign invaders |
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Term
-red bone marrow produced
-polymorphonuclear (many-shaped nucleus)
-granular cytoplasm when stained |
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Definition
|
|
Term
| Three types of Granular WBC's |
|
Definition
Neutrophils
Eosinophils
Basophils |
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Term
| Produced/derived from the same stem cell (hemocytoblast) as RBC& WBC |
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Definition
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|
Term
-Specializes or differentiates into a megokaryocyte which is now destined to produce platelets
- it sheds cytoplasm and membranes
- frgaments and forms platelets
- move in circulation |
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Definition
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Term
|
Definition
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Term
|
Definition
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|
Term
repair slightly damaged blood vessel linings
initiate chain reaction for clotting |
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Definition
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|
Term
| blood vessel other than a capillary is damaged. |
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Definition
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Term
|
Definition
a. smooth muscle contracts in wall of vessel
b. spasm of contractoin
c. reduces blood flow until other mechanisms are working
d. initiated due to damage of smooth muscle cells, nerve reflex fibers, and pain receptors. |
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|
Term
| platelets contact parts of damaged vessel such as collagen under epithelium and then platelets undergo changes. |
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Definition
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Term
| Secrete substances which increase stickiness of platelets and vasoconstrictors (ADP, Prostaglandin, Serotonin) |
|
Definition
| Platelet Release Reaction |
|
|
Term
-for mass --> more and more platelets adhere
- vere effective in preventing blood loss in small vessels |
|
Definition
|
|
Term
| reinforces the platelet plug with fibrin threads that act as a molecular glue for the aggregated platelets. |
|
Definition
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|
Term
|
Definition
Stage 1: formation of prothrombin activator
Stage 2: conversion of prothrombin into enzyme thrombin
Stage 3: conversion of soluble fibrinogen into soluble fibrin strands. |
|
|
Term
| What happens if a person has a low fat metabolism? |
|
Definition
| This would result in low vitamin K= poor or no clotting. |
|
|
Term
| Intrinsic Vs Extrinsic paths to prothrombin activator |
|
Definition
Intrinsic= internal damage in vessel wall
Extrinsic= tissue damage
Intrinsic= damage detected as blood flows through vessel and very slow
Extrinsic= tearing of blood vessels and tissues, much fasters, occurs in seconds.
Both end with Factor X produced |
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Term
tightening and consolidatoin of the clot, drying, squeezing out fluid.
Knits vessel ends together, initiates healing of damaged vessel |
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Definition
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Term
|
Definition
| clot dissolution via thrombin, lysozome enzymes, and TPA come together and activate plasminogen which is already in the blood in an inactive form. Activated Plasmin dissolves clot. |
|
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Term
| Three anticoagulants to prevent unnecessary clotting |
|
Definition
-protocyclin
-Heparin
-Wayfarin |
|
|
Term
| blood clot in a closed vein or artery |
|
Definition
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|
Term
| a clot, fat from a broken bone, air bubble, or other debris traveling in the blood stream. Example lodge in lungs--> pulmonary emolism |
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Definition
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|
Term
| if you have protein in your blood |
|
Definition
|
|
Term
| if you do not have the protein |
|
Definition
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