Term
|
Definition
| Measels (Rubeola - paramyxovirus) |
|
|
Term
| Congenital (AD) aneurysmal telangiectasia beneath mucosal surfaces of oral cavity/lips |
|
Definition
| Rendu-Osler-Weber syndrome |
|
|
Term
| Dormant virus in the trigeminal nerve ganglia |
|
Definition
|
|
Term
|
Definition
| Cytologic smear used to evaluate HSV infxn |
|
|
Term
| Multinucleated cell with glassy nuclei and intranuclear inclusions |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Hand-foot-and-mouth disease |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Separation between the dermis and epidermis |
|
Definition
|
|
Term
| Targetoid lesion on hands and feet |
|
Definition
|
|
Term
| Red, depapillated blostches surrounded by elevated, yellow-white C-shaped border |
|
Definition
|
|
Term
| Benign migratory glossitis |
|
Definition
|
|
Term
| Recurrent aphthae or cancer sores |
|
Definition
|
|
Term
| Painful lesion of the movable mucosa |
|
Definition
|
|
Term
| Destructive, necrotizing, non-healing ulcer of the nose, palate and sinuses |
|
Definition
|
|
Term
| Lesion of the medial dorsal surface of the tongue in adults |
|
Definition
| Median Rhomboid Glossitis |
|
|
Term
| Diffuse keratosis with many umbilicated nodules |
|
Definition
|
|
Term
| Solar keratosis of the lip |
|
Definition
|
|
Term
| Hyperkeratotic, slow growing (often remits) with central ulcer or umbilicus on the sun-exposed areas of skin/lips |
|
Definition
|
|
Term
| Benign lesion that mimics ulcerated SCC |
|
Definition
| Necrotizing sialometaplasia |
|
|
Term
| White pseudomembrane that can be scraped off, revealing red, ulcerated mucosal surface |
|
Definition
|
|
Term
| Lace-like white mucosal lesion |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Oral hairy leukoplakia causatives |
|
Definition
|
|
Term
| Red-Blue Lesion associated with pregnancy |
|
Definition
|
|
Term
| Cyst surrounding crown of the tooth + ameloblastic remnants |
|
Definition
| Dentigerous/Eruptive cyst |
|
|
Term
| Cyst surrounding root of the tooth without ameloblastic remnants |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Cyst arising from the remnants of the dental lamina |
|
Definition
|
|
Term
| Cyst lined by squamous epithelium with basaloid proliferation |
|
Definition
|
|
Term
| Plexiform epithelium proliferation in fish-net patter with peripheral columnar ameoloblast-like cells |
|
Definition
|
|
Term
| Ameloblastoma mets to LN with out change in morphology |
|
Definition
|
|
Term
| Tumor of fibroblastic proliferation in region of the periodontal ligament |
|
Definition
|
|
Term
| Spindle shaped cells and scattered collagen fibers through loose mucoid material, resembling dental papilla |
|
Definition
|
|
Term
| MC site for salivary gland malignancy |
|
Definition
| Parotid gland, superficial lobe |
|
|
Term
| Most common oral neoplasm |
|
Definition
| Pleomorphic adenoma (mixed, benign tumor) |
|
|
Term
| Malignant degeneration of Bartholin glands |
|
Definition
|
|
Term
| Papillary frons lined by double row of columnar oncocytic cells |
|
Definition
|
|
Term
| Papillary cystadenoma lymphomatosum |
|
Definition
|
|
Term
| Lymphoid stroma with germinal center projecting into cystic space |
|
Definition
|
|
Term
| Parotid mass in elderly female showing pink, polygonal oncocytic cells |
|
Definition
|
|
Term
| S-100 (+), SM actin (+), and cytokeratin (+) |
|
Definition
|
|
Term
| Most common parotid cancer |
|
Definition
|
|
Term
| Multilocular posterior mandibular radiolucency |
|
Definition
|
|
Term
| MC malignancy in the submandibular gland |
|
Definition
|
|
Term
| "Swiss cheese" pattern of monotonous basaloid cells in ovoid cylinders |
|
Definition
|
|
Term
| Parotid, pseudoencapsulated, lobulated tumor |
|
Definition
|
|
Term
| "Indian file" arrangement at he periphery of the tumor |
|
Definition
| Polymorphois low grade adenocarcinoma |
|
|
Term
| Lobular carcinoma/terminal duct carcinoma |
|
Definition
| Polymorphois low grade adenocarcinoma |
|
|
Term
| MC soft tissue tumor in adults |
|
Definition
|
|
Term
| Lipoblasts seen in the proximal extremity or retroperitoneum |
|
Definition
|
|
Term
| Soft tissue tumor that develop suddenly and grows rapidly |
|
Definition
|
|
Term
| Nodular fasciitis and Myositis ossificans |
|
Definition
|
|
Term
|
Definition
| Myositis ossificans if in adductor muscles |
|
|
Term
| Palmar superificial fibromatosis |
|
Definition
|
|
Term
| Penile superificial fibromatosis |
|
Definition
|
|
Term
| Gardner's syndrome association |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Herringbone storiform pattern |
|
Definition
|
|
Term
| Soft, hemorrhagic, unencapsulated mass with fish-flesh pattern & necrosis |
|
Definition
|
|
Term
| Storiform pattern with spindle cells in the dermis with collagen wrapping around the cells |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Common tumor of the dermis and subcutis |
|
Definition
|
|
Term
|
Definition
| Dermatofibrosarcoma protruberans (DFSP) |
|
|
Term
| COL1A1 + PDGF gene fusion |
|
Definition
| Dermatofibrosarcoma protruberans (DFSP) |
|
|
Term
| Infiltrative dermal neoplasm with cellular infiltrative fibrohistiocytic proliferation with a storiform pattern |
|
Definition
| Dermatofibrosarcoma protuberans (DFSP) |
|
|
Term
| MC soft tissue sarcoma of adults |
|
Definition
| High grade pleomorphic sarcoma |
|
|
Term
| Malignant firbous histiocytoma (MFH) |
|
Definition
| High grade pleomorphic sarcoma |
|
|
Term
| Giant cell or inflammatory variety |
|
Definition
| High grade pleomorphic sarcoma |
|
|
Term
|
Definition
|
|
Term
| Spindle cells aligned at right angles with no mitosis |
|
Definition
|
|
Term
| Spindle cells aligned at right angles with pleomorphic, cigar-shaped nuclei with mitosis |
|
Definition
|
|
Term
| Embryonal, pleomorphic, and alveolar patterns |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| SS18-SS1, SSX2, or SSX4 fusion genes (notes) |
|
Definition
|
|
Term
| SYT-SSX fusion genes (slides) |
|
Definition
|
|
Term
| Deep mass near large joints with calcified concretions |
|
Definition
|
|
Term
| EMA (+), keratin (+), CD99 (+) |
|
Definition
|
|
Term
|
Definition
| Endothelial markers for vascular tumors |
|
|
Term
| Severe nocturnal pain relieved by aspirin |
|
Definition
|
|
Term
| Target lesion < 2cm in the cortex of long bones |
|
Definition
|
|
Term
| Dull, achy bone pain not relieved by aspirin |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Mosaic pattern or "jigsaw" pattern |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Chalkstick-type fractures of the leg |
|
Definition
|
|
Term
| Enlarged craniofacial bones, high-output cardiac failure, tibial bowing |
|
Definition
|
|
Term
| MC cause of osteonecrosis |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Osteomyelitis in Sick Cell Patients |
|
Definition
|
|
Term
|
Definition
| Osteomyelitis due to Syphilis |
|
|
Term
|
Definition
| Osteomyelitis due to Syphilis |
|
|
Term
|
Definition
| Osteomyelitis of the vertebrae |
|
|
Term
| Lytic focus of bone destruction surrounded by zone of sclerosis |
|
Definition
|
|
Term
| Craniotabes, rachitic rosary, pigeon breast, bowing of legs |
|
Definition
| Rickets (Vit D deficiency) |
|
|
Term
|
Definition
|
|
Term
| MC malignant cartilage tumor |
|
Definition
|
|
Term
| RB gene + p53 mutation in bone tumors |
|
Definition
|
|
Term
| Codman Triangle (Sun-Burst) |
|
Definition
|
|
Term
| MC matrix producing primary bone tumor |
|
Definition
|
|
Term
| MC benign tumor of the bone |
|
Definition
|
|
Term
| Cartilage cap tumor looks like a mushroom-shaped growth of cartilage |
|
Definition
|
|
Term
| Bulky, translucent bluish gray, glistening tumors |
|
Definition
|
|
Term
| 2nd MC malignant cartilage tumor |
|
Definition
|
|
Term
| Neoplastic cartilage in the medulla of the bone |
|
Definition
|
|
Term
| Snow storm appearance with endosteal scalloping |
|
Definition
|
|
Term
| Hyaline cartilage in the medullary cavity of bone |
|
Definition
|
|
Term
| C or O ring sign on radiograph |
|
Definition
|
|
Term
| Sheets of monomorphic pink chondroblasts with scant "chicken wire" matrix |
|
Definition
|
|
Term
| Increased cellularity with scattered giant cells |
|
Definition
|
|
Term
| Well-defined geographic lucency with spotty calcifications |
|
Definition
|
|
Term
| Sarcoma producing fibroblastic collagen in herringbone pattern |
|
Definition
|
|
Term
|
Definition
| Ewing Sarcoma/Primitive Neuroectodermal Tumor |
|
|
Term
| (11;22)(q24;q12) translocation |
|
Definition
| Ewing Sarcoma/Primitive Neuroectodermal Tumor |
|
|
Term
| Homer-Wright rosettes in bone tumor |
|
Definition
| Primitive Neuroectodermal Tumor |
|
|
Term
| MC primary malignant bone sarcoma in kids |
|
Definition
| Ewing Sarcoma/Primitive Neuroectodermal Tumor |
|
|
Term
| Onion-skinning periosteal reaction |
|
Definition
| Ewing Sarcoma/Primitive Neuroectodermal Tumor |
|
|
Term
|
Definition
|
|
Term
| Tumor arising from monocyte precursors and expressing RANKL |
|
Definition
|
|
Term
| Only tumor of the epiphysis (Pathoma) |
|
Definition
|
|
Term
| Buldgin soft tissue mass confined by shell of reactive bone |
|
Definition
|
|
Term
| Osteolytic Metastatic Disease |
|
Definition
| Breast, kidney, lung, GI, melanoma |
|
|
Term
| Osteoblastic Metastatic Disease |
|
Definition
|
|
Term
| Type of Collagen in Articular Hyaline Cartilage |
|
Definition
|
|
Term
|
Definition
| Osteonecrosis: osteoclasts absorb necrotic bone |
|
|
Term
|
Definition
|
|
Term
| Morning stiffness that lasts about 10 minutes with deep, aching pain made worse with use |
|
Definition
|
|
Term
|
Definition
| Osteoarthritis, Rheumatoid arthritis |
|
|
Term
|
Definition
| Osteophytes at DIPs in osteoarthritis |
|
|
Term
|
Definition
| Osteophytes at PIPs in osteoarthritis |
|
|
Term
| Subchondral cysts, residual articular cartilage, Eburnation |
|
Definition
|
|
Term
| Morning stiffness that lasts > 1 hour improves throughout the day |
|
Definition
|
|
Term
| Symmetric arthritis and arthritis of the hand joints |
|
Definition
|
|
Term
| Radial deviation of the wrists and ulnar deviation of the fingers |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| IgM antibbody against the Fc portion of IgG |
|
Definition
|
|
Term
| Fibrinoid necrosis and peripheral palisading of histiocytes |
|
Definition
|
|
Term
| < 16 y/o with (+) ANA, and systemic arthritis in large joints |
|
Definition
| Juvenile Rheumatoid Arthritis |
|
|
Term
| Rheumatoid Arthritis , Splenomegaly, neutropenia |
|
Definition
|
|
Term
| Ulcerative colitis and Sjogren syndrome associations |
|
Definition
|
|
Term
|
Definition
| Rheumatoid Arthritis diagnosis |
|
|
Term
|
Definition
| Early RA or at risk to develop RA |
|
|
Term
| Skin or soft tissue lesion characterized by fibrinoid necrosis and peripheral palisading of histiocytes |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Seronegative spondyloarthropathies |
|
|
Term
|
Definition
| Ankylosing Spondyloarthritis |
|
|
Term
| Arthritis, nongonococcal urethritis/cervicitis, and conjunctivitis |
|
Definition
|
|
Term
| Sausage finger or toe, calcaneal spurs, and bony outgrowths |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Arthritis of the small joints of the hands, feet that may extend to larger joints |
|
Definition
|
|
Term
| Remitting and migratory arthritis involving large joints |
|
Definition
| Lyme arthritis (Borrelia burgdorferi) |
|
|
Term
|
Definition
| Genetic predisposition for Gout, absence of enzye = lesch Nyhan syndrome |
|
|
Term
| Monosodium urate crystals |
|
Definition
|
|
Term
| Needle-like, (-) birefrengence |
|
Definition
|
|
Term
| Rhomboid crystals, weakly (+) birefrengence |
|
Definition
|
|
Term
| Calcium pyrophosphate crystals |
|
Definition
|
|
Term
| Linear calcifications of articular cartilage |
|
Definition
|
|
Term
| Colony stimulating factor I |
|
Definition
| Tenosynovial giant cell tumor |
|
|
Term
| Diffuse, Finger-like projections covering synovial surface |
|
Definition
| Pigmented villonodular synovitis |
|
|
Term
| Double line sign with increased bone density on radiograph |
|
Definition
|
|
Term
| Pancreas surrounds duodenum |
|
Definition
|
|
Term
| Failure of the dorsal and ventral ducts of the pancreas to fuse |
|
Definition
|
|
Term
| Most common congenital anomaly of the pancreas |
|
Definition
|
|
Term
| MCC of acute pancreatitis in North American males |
|
Definition
|
|
Term
| MCC of acute pancreatitis in North American females |
|
Definition
|
|
Term
| MCC of acute pancreatitis in kids |
|
Definition
|
|
Term
| Rapid onset of severe epigastric pain radiating to the back |
|
Definition
|
|
Term
| Eccymotic discoloration around umbilicus |
|
Definition
|
|
Term
| Eccymotic discoloration of the flank |
|
Definition
|
|
Term
| Triad of Chronic Pancreatitis |
|
Definition
| Calcification or Pseudocysts, steatorrhea, diabetes mellitus |
|
|
Term
| MCC of chronic pancreatitis in adults |
|
Definition
|
|
Term
| MCC of chronic pancreatitis in kids |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Recurrent pulmonary infections (bronchiectasis) and Pancreatic Insufficiency (Acinar/Exocrine gland Atrophy) |
|
Definition
|
|
Term
| CFTR gene mutation on chromosome 7 |
|
Definition
|
|
Term
| Codon 12 of KRAS point mutation |
|
Definition
| Andocarcinoma of the pancreas |
|
|
Term
| Inactivation of p16 and p53 |
|
Definition
| Andocarcinoma of the pancreas |
|
|
Term
| MC location of pancreatic cancer |
|
Definition
| Head of the pancreas (60%) |
|
|
Term
| Dilated gallbladder palpable in the RUQ without pain |
|
Definition
|
|
Term
| Migratory thrombophelbitis |
|
Definition
|
|
Term
| MC sites of pancreatic adenocarcinoma metastasis |
|
Definition
|
|
Term
|
Definition
| Pancreatic cancer biomarker, (also in GI cancer) |
|
|
Term
|
Definition
| Pancreatic cancer biomarker (also seen in GI, lung, and breast CA) |
|
|
Term
| Hypoglycemia (↑ insulin and C-peptide) |
|
Definition
|
|
Term
| Migratory necrolytic erythema |
|
Definition
|
|
Term
| DM, steatorrhea, gallstones, and achlorhydria |
|
Definition
|
|
Term
|
Definition
| Glucose transport protein in adipose tissue & striated muscle |
|
|
Term
|
Definition
| Glucose transport protein in the liver |
|
|
Term
| Lymphocytic infiltration of Pancreatic B cells |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Anti-islet cell auto antigen |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Anti-glutamic acid decarboxylase (GAD) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Hyperglycemia, acidosis, ketosis |
|
Definition
|
|
Term
|
Definition
| Ketone bodies (Ketoacidosis) |
|
|
Term
| B-hydroxybuteric acid (most abundant) |
|
Definition
| Ketone bodies (Ketoacidosis) |
|
|
Term
|
Definition
| Sweet-smelling breath in DKA |
|
|
Term
| Deep, rapid breathing in DKA |
|
Definition
|
|
Term
| Insulin deficiency and unregulated glucagon secretion from alpha cells of the pancreas |
|
Definition
|
|
Term
| Amylin deposition in pancreatic islets |
|
Definition
|
|
Term
| ↓ synthesis and translocation of GLUT4 in muscle and fat cells |
|
Definition
|
|
Term
| Hyperosmolar nonketotic coma |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Defect in insulin secretion causing onset of DM < 25 without obesity or autoantibodies |
|
Definition
|
|
Term
| Most severe types of B cell insulin secretory defects |
|
Definition
|
|
Term
| Podocyte nuclear transcription factor 4A mutation, chr 20 |
|
Definition
|
|
Term
| Podocyte nuclear transcription factor 1A mutation, chr 12 |
|
Definition
|
|
Term
| Cataracts, proliferative retinopathy, and glaucoma |
|
Definition
|
|
Term
| Advanced glycation end products (AGEs) |
|
Definition
|
|
Term
|
Definition
| Advanced glycation end product |
|
|
Term
| Fraction of Hb where glucose has been glycated to Hb molecule |
|
Definition
|
|
Term
| Protein Kinase C Products (activated by ↑Diacylglycerol) |
|
Definition
| VEGF, TGF-B, PAI-1, pro-inflammatory cytokines |
|
|
Term
|
Definition
| Glucose -> Sorbitol conversion enzyme |
|
|
Term
| Accumlation of sorbitol and fructose |
|
Definition
|
|
Term
| MCC of death in Diabetics |
|
Definition
| Coronary Artery Thrombosis (MI) |
|
|
Term
| Nodular glomerulosclerosis in DM |
|
Definition
| Kimmelstiel Wilson disease |
|
|
Term
| PAS +, laminated hyaline nodules at the periphery of the glomerulus |
|
Definition
| Kimmelstiel Wilson disease |
|
|
Term
| Earliest sign of kidney involvement in DM |
|
Definition
|
|
Term
| Derived from Rathke's pouch |
|
Definition
|
|
Term
| Derived from outpouching of floor of 3rd ventricle |
|
Definition
|
|
Term
| Only pituitary hormone under inhibitory control |
|
Definition
|
|
Term
|
Definition
| Somatotrophs, Lactotrophs |
|
|
Term
|
Definition
| Corticotrophs, Thyrotrophs, Gonadotrophs |
|
|
Term
| Acute massive hemorrhage into pituitary adenoma |
|
Definition
|
|
Term
| MC type of pituitary adenoma |
|
Definition
|
|
Term
| ↑ prolactin, ↓GnRH and LH, FSH |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Prolactin Inhibitory Factor |
|
Definition
|
|
Term
| ↓ (+) reticulin stain and monomorphous cell population |
|
Definition
|
|
Term
| Mutant GTPase deficient alpha subunit of G-protein, Gs |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Giantism is kids, Acromegaly in adults |
|
Definition
|
|
Term
| MCC of death in GH Adenoma |
|
Definition
|
|
Term
| Corticotroph Cell Adenoma |
|
Definition
|
|
Term
| Rapid enlargement of pituitary adenoma following removal of adrenal glands (loss of feedback inhibition) |
|
Definition
|
|
Term
| Poor lactation and loss of pubic hair in post-partum women |
|
Definition
|
|
Term
| Post-partum necrosis of anterior pituitary |
|
Definition
|
|
Term
| Arachnoid mater and CSF herniation into sella |
|
Definition
| Primary Empty Sella Syndrome |
|
|
Term
| ADH deficiency (pituitary) or kidneys unresponsive to ADH on V2 receptors of the collecting duct |
|
Definition
|
|
Term
| Large amounts of dilute urine with low specific gravity |
|
Definition
|
|
Term
|
Definition
| Syndrome of inappropriate ADH secretion (SIADH) |
|
|
Term
| Small amounts of concentrated urine with high specific gravity |
|
Definition
|
|
Term
|
Definition
| Paraneoplastic syndrome (Small cell lung CA) |
|
|
Term
| "Machine oil" consistency, cystic tumor with calcifications |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Propylthiouracil, Mercaptoimidazole |
|
Definition
| Goitrogens (suppress T3, T4 production) |
|
|
Term
|
Definition
| Goitrogens (suppress T3, T4 production) |
|
|
Term
| Veggies - cabbage, brussel sprouts, cauliflower, turnips |
|
Definition
| Goitrogens (suppress T3, T4 production) |
|
|
Term
| Hyperplastic follicles with scalloping of thyroid colloid |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Pretibial myxedema and pro-optosis |
|
Definition
|
|
Term
| IgG immunoglobulin that binds TSH receptor |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Long-acting thyroid stimulator (LATS) |
|
Definition
|
|
Term
| Thyroid growth stimulating immunoglobulins |
|
Definition
|
|
Term
| TSH binding inhibitor immunoglobulins |
|
Definition
|
|
Term
| Papillae that lack fibrovascular core project into follicular lumen |
|
Definition
|
|
Term
| Hyperplastic follicular cells with decreased colloid and increased lymphoid tissue |
|
Definition
|
|
Term
| ↑TSH and elevated free T4 |
|
Definition
| TSH-secreting pituitary adenoma |
|
|
Term
| Graves Disease Associations |
|
Definition
| Lupus, DM1, pernicuous anemia, addison's disease |
|
|
Term
|
Definition
|
|
Term
| Recurrent episodes of thyroid hyperplasia and involution |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Toxic multinodular goiter with hyperthyroidism |
|
Definition
|
|
Term
| Child with mental retardation, short stature, coarse facial features, umbilical hernia, and skeletal abnormalities |
|
Definition
|
|
Term
| Hoarse cry and somnolence |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Transient thyrotoxicosis followed by hypothyroidism |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Autoantibodies against thyroglobulin, thyroid peroxidase, TSH receptor, and iodine receptor |
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Definition
|
|
Term
|
Definition
|
|
Term
| Hashimoto's thyroiditis (signs of damage, NOT mediators) |
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Definition
| anti-thyroglobulin and antimicrosomal bodies |
|
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Term
|
Definition
|
|
Term
| Lymphocytes, Plasma cells, and germinal centers |
|
Definition
|
|
Term
| Hashimoto's thyroiditis associations |
|
Definition
| DM1, SLE, myasthenia gravis, Sjorgrens, increased risk of lymphoma |
|
|
Term
| Small thyroid with fibrosis restricted within gland (not beyond capsule) |
|
Definition
| Atrophic variant of Hashimoto's thyroiditis |
|
|
Term
|
Definition
| Infectious Thyroiditi, subacute granulomatous thyroiditis |
|
|
Term
|
Definition
| Subacute granulomatous thyroiditis |
|
|
Term
| Tender thyroid following viral infection |
|
Definition
| Subacute granulomatous thyroiditis |
|
|
Term
| Neck pain radiating to the jaw, throat and ears, especially when swallowing |
|
Definition
| Subacute granulomatous thyroiditis |
|
|
Term
| Transient hyperthyroid (2-6 wks) followed by transient hypothyroid (2-8 wks) and then resolves |
|
Definition
| Subacute granulomatous thyroiditis |
|
|
Term
|
Definition
| Subacute granulomatous thyroiditis |
|
|
Term
| Multinucleated giant cells surrounding pools of colloid |
|
Definition
| Subacute granulomatous thyroiditis |
|
|
Term
| Painless, post-partum throiditis |
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Definition
| Subacute Lymphocytic Thyroiditis |
|
|
Term
| Hashimotos varient with lymphocytes but no plasma cells or lymphocytes |
|
Definition
| Subacute Lymphocytic Thyroiditis |
|
|
Term
| "Hard as wood" nontender thyroid in middle aged female |
|
Definition
|
|
Term
| Extensive fibrosis involving surrounding structures of the neck |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Enlarging cervical LN in a young female (Type of thyroid CA) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Mutation in tyrosine receptors (RET/PTC, NTRK1) or activating mutation in BRAF |
|
Definition
|
|
Term
| Associated with ionizing radiation in childhood |
|
Definition
|
|
Term
| Papillary Carcinoma Associations |
|
Definition
| Gardner's Syndrome and Cowden's disease |
|
|
Term
| Branching papillae with fibrovascular stalk |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Intranuclear grooves/inclusions - thyroid |
|
Definition
|
|
Term
| Psammoma bodies - thyroid |
|
Definition
|
|
Term
| Slowly enlarging painless nodule in an older female (Thyroid CA) |
|
Definition
|
|
Term
| Thyroid cancer in iodine deficient regions |
|
Definition
|
|
Term
| Single, encapsulated "cold" nodule |
|
Definition
|
|
Term
| Thyroid cancer mets via hematogenous spread |
|
Definition
|
|
Term
| Neuroendocrine tumor of C-cells or parafollicular cells |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Familial Medullary Carcinoma |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Amyloid deposition in stroma |
|
Definition
|
|
Term
| Undifferentiated tumor of thyroid follicular epithelium |
|
Definition
| Anaplastic Thyroid Carcinoma |
|
|
Term
| Persistence of foramen cecum seen in neck midline |
|
Definition
| Thyroglossal duct or cyst |
|
|
Term
| MC cause of clinically apparent hypercalcemia |
|
Definition
|
|
Term
| MC cause of clinically silent hypercalcemia |
|
Definition
|
|
Term
|
Definition
| Parathyroid adenoma (Primaryhyperparathyroidism) |
|
|
Term
| Parathyroid has ↓ sensitivity to extracellular calcium (mutation in Ca2+ receptors) |
|
Definition
| Familial hypocalciuric hypercalcemia |
|
|
Term
| Solitary; Increase in chief cells without stromal fat and thin capsule |
|
Definition
| Parathyroid adenoma (Primary hyperparathyroidism) |
|
|
Term
| All 4 glands involved with ↑Chief cells, ↓stromal fat |
|
Definition
| Primary hyperplasia (Primary hyperparathyroidism) |
|
|
Term
| BM with fibrosis, hemorrhage and cyst formation |
|
Definition
|
|
Term
|
Definition
| Primary hyperparathyroidism |
|
|
Term
| Bone, stones, moans, and groans (bone pain, nephrolithiasis, GI ulcer, and CNS depression/seizures) |
|
Definition
| Primary hyperparathyroidism |
|
|
Term
| Renal failure causing phosphate retention |
|
Definition
| Secondary hyperparathyroidism |
|
|
Term
| Tetany seen in hypocalcemia; abnormal stimulation of the facial nerve when tapped at angle of the jaw |
|
Definition
|
|
Term
| Tetany seen in hypocalcemia; BP cuff inflated above systolic BP and held for 3 minutes, occluding brachial artery and inducing spasm of the hand/forearm muscles |
|
Definition
|
|
Term
|
Definition
|
|
Term
| End organ resistance to PTH in target tissue |
|
Definition
|
|
Term
| Short stature with round face/short neck and short metacarpals/tarsals |
|
Definition
|
|
Term
| Acute adrenal hemorrhagic necrosis with N. meningitidis |
|
Definition
| Waterhouse-Friderichsen syndrome |
|
|
Term
|
Definition
| Waterhouse-Friderichsen syndrome |
|
|
Term
| Primary acute adrenocortical insufficiency |
|
Definition
|
|
Term
| Primary chronic adrenocortical insufficiency |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Autoimmune polyendocrinopathy syndrome type 1 (aka Autoimmune Addison's Disease) |
|
|
Term
| Mucocutaneous candidiasis, ectodermal dysplasia, hypoparathyroidism, hypogonad, pernicious anemia |
|
Definition
| Autoimmune polyendocrinopathy syndrome type 1 |
|
|
Term
| Adrenal insufficiency + Autoimmune thyroiditis or DM1 |
|
Definition
| Autoimmune polyendocrinopathy syndrome type 2 |
|
|
Term
| Electrolyte imbalance, hyperpigmentation, nausea, hypoglycemia |
|
Definition
|
|
Term
| Low-renin hyperaldosteronism |
|
Definition
| Primary hyperaldosteronism |
|
|
Term
|
Definition
|
|
Term
| Exogenous ACTH production |
|
Definition
| Small cell CA of lung, carcinoid tumors of bronchi, medullary thyroid cancer, islet cell tumors of pancreas |
|
|
Term
| Bilateral cortical adrenal cortical hyperplasia |
|
Definition
| Cushing Dz, Cushing Syndrome (anything with ↑ACTH and cortisol) |
|
|
Term
| Crooke hyaline change in pituitary |
|
Definition
|
|
Term
| Intermediate keratin filaments within corticotrophs |
|
Definition
|
|
Term
| One side of the adrenal enlarged while the other is atrophied |
|
Definition
| Adenoma of zona fasciculate |
|
|
Term
|
Definition
| Exogenous production of cortisol or intake of hormones (weight lifters) |
|
|
Term
| AR disorders of sexual differentiation |
|
Definition
| Congenital Adrenal Hyperplasia |
|
|
Term
| CYP21A2 mutation, most commonly involving 21-hydroxylase def. |
|
Definition
|
|
Term
| ↓mineralocorticoids (↓Na+, hypotension), ↓cortisol, ↑ androgens (virilization) |
|
Definition
| 21-hydroxylase deficiency (CAH) |
|
|
Term
| Aldosterone-secreting adenoma |
|
Definition
|
|
Term
| PAS reactive cytoplasmic inclusions in z. fasiculata |
|
Definition
|
|
Term
| Tumor of the adrenal medulla |
|
Definition
|
|
Term
|
Definition
|
|
Term
| ↑ metanephrines & Vanillylmandelic acid |
|
Definition
|
|
Term
| Extra-adrenal pheochromocytoma |
|
Definition
|
|
Term
| Pheochromocytoma Disease Associations |
|
Definition
| MEN IIA and B, NF1, Von Hippel Lindau, Sturge-webber |
|
|
Term
| Small nests and alveolar groups of cells (zellballen) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| 3 Ps: Parathyroid, Pancreas, Pituitary Adenoma |
|
Definition
|
|
Term
| Adrenal cortical hypertrophy - with 3p's |
|
Definition
|
|
Term
| MENI most common presentation |
|
Definition
|
|
Term
| MENI leading cause of mortality |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Medullary thyroid cancer, pheochromocytoma, parathyroid hyperplasia |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Single AA mutation in RET |
|
Definition
|
|
Term
| Multiple mucosal neuroma syndrome |
|
Definition
|
|
Term
| Medullary thyroid cancer, pheochromocytoma, neuromas of oral cavity, conjuctiva, genital mucosa and a tall, thing marfanoid-like body habitus |
|
Definition
|
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