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Definition
| One of a pair of genes on a specific location of a chromosome that control the same trait |
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Definition
| Study of how a drug affects the body |
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Definition
| Study of inherited differences or variations in drug metabolism & response |
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Definition
| Study of role of inheritance in individual variation in drug response. Refers to general study of all of the many different genes that determine drug behavior |
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Definition
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Definition
| Change in a single nucleotide of the genome that occurs in 1% or less of the pop. |
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Definition
| Presence of 2+ alleles for a gene or DNA sequence in a population |
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| single nucleotide polymorphism |
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Definition
| Point mutation occurring in >1% of pop. |
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Definition
| study of changes in protein expression of individuals under various conditions |
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Definition
| study of potential interaction between dietary nutrients and genotypic expression |
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Definition
| study of alteration of metabolites and metabolic pathways under various conditions |
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Definition
| sturdy of how genomes are affected by toxins or other environmental factors |
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Definition
| unwinds DS DNA to form SS DNA |
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Term
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Definition
| coats the SS DNA and prevents re-annealing of the DNA strands |
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Definition
| joins together Okazaki fragments to form long strand |
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Term
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Definition
| synthesizes short RNA primers that are needed to start the replication process |
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Term
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Definition
| enzyme that strings together nucleotides |
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Definition
| accessory protein that holds the polymerase onto the DNA |
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Definition
| removes primers that began replication |
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Definition
| substitution of one pyrimidine for another (T & C) or one purine for another (A and G) |
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Term
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Definition
| one purine is replaced by a pyrimidine |
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Definition
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Definition
| cleaves 3' end and adds poly A tail |
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Definition
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Definition
| crossover between nonhomologous chromosomes |
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