Term
| What does the virion structure consist of? |
|
Definition
1) Nucleic acid (either RNA or DNA, never both)
2) Capsid protein
3) +/- lipid membrane envelope derived from host cell |
|
|
Term
| Envelope proteins that differentiate influenza strains? |
|
Definition
| Hemagglutinin & Neuraminidase (e.g. H1N1) |
|
|
Term
| Which medically relevant type of virus is "complex" in shape? |
|
Definition
|
|
Term
| What common virus performs "cell transformation," turning host cells cancerous? |
|
Definition
|
|
Term
| What common virus forms immune complexes? |
|
Definition
|
|
Term
| What common virus lies dormant and causes asymptomatic disease until it is triggered? |
|
Definition
|
|
Term
|
Definition
| Blocks attachment of virus to host cell |
|
|
Term
| Amantidine/rimantidine MOA? |
|
Definition
| Prevent uncoating once virus enters cell |
|
|
Term
| Acyclovir/ganciclovir MOA? |
|
Definition
| Inhibit DNA/RNA synthesis (Targets viral rather than host nucleic acids by only activating in response to phosphorylation by viral kinases) |
|
|
Term
|
Definition
| Arthropod-borne virus, spread by blood-sucking arthropods; all have RNA genome, most have lipid envelope |
|
|
Term
| what type of arbovirus is Chikungunya? |
|
Definition
| Togavirus (alpha subtype) |
|
|
Term
| What type of virus cause Dengue, West Nile, and yellow fever? |
|
Definition
|
|
Term
| All US pregnant women are screened for what virus? |
|
Definition
|
|
Term
| Congenital rubella abnormalities? |
|
Definition
| Ocular- glaucoma, cataracts; CV- PDA, atrial/ventricular septal defects; hearing impairment-deafness; CNS- mental retardation |
|
|
Term
| T/F- infection w/ rubella confers immunity |
|
Definition
|
|
Term
| Which illness has 2 subtypes: urban/jungle fever? |
|
Definition
|
|
Term
| What type of nucleic acid is the virus the causes Dengue fever? |
|
Definition
|
|
Term
| What illness is transmitted by the mosquito Aedes aegypti? |
|
Definition
|
|
Term
|
Definition
| Nonbleeding and bleeding types |
|
|
