Term
| What is Polycythemia Vera? |
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Definition
| Stemm cell abnormality, myeloproliferative Disorder "Cancer" |
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Term
| What is another term for Polycythemia? |
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Definition
|
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Term
|
Definition
| WBC with granules in cytoplasm |
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Term
| What are the 3 types of granulocytes? |
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Definition
| Neutrophils, basophils, eosinohils |
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Term
|
Definition
| WBC with no granules in cytoplasm |
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Term
| What are the main types of agranulocytes? |
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Definition
| monocytes, lymphocytes (T and B cells, plasma cells) |
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Term
| What are the normal levels of neutrophils? |
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Definition
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Term
| What are the normal levels of eosinophils? |
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Definition
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Term
| What is the myelocytic cell line? |
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Definition
|
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Term
| What are the 5 subtypes of phagocytes? |
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Definition
| neutrophils, basophils, eosinophils, monocytes, macrophages |
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Term
|
Definition
| An increased number of neutrophils |
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Term
|
Definition
| A decreased number of neutrophils |
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Term
|
Definition
| An increased number of eosinophils |
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Term
|
Definition
| An increased number of basophils, RARE! |
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Term
|
Definition
| increased number of lymphocytes |
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Term
|
Definition
| A decreased number of lymphocytes |
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Term
| What is Bruton's Syndrome? |
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Definition
| A B cell immunodeficiency |
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Term
| What is DiGeorge's Syndrome? |
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Definition
| A T cell immunodeficiency due to thymus dysfunction |
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Term
| What is a blood cell neoplasm? |
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Definition
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Term
| What is a myeloproliferative BC neoplasm? |
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Definition
| myeloid cell line related neoplasms |
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Term
| Name two types of myeloproliferative BCN's |
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Definition
| myelodysplastic syndrome, myelogenous leukemias |
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Term
| What are lymphoproliferative BCN's? |
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Definition
| lymphomas, multiple myeloma, lymphocytic leukemias |
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Term
| What is myelodysplastic Syndrome? |
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Definition
| results in cytopenia of RBC, platelets, granulocytes |
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Term
| Name the major locations of lymphatic tissue (5) |
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Definition
| Spleen, thymus, tonsils, bone marrow, lymph nodes |
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Term
| What is Burkitt's Lymphoma? |
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Definition
| b-cell lymphoma, associated with Epstien-Barr Virus |
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Term
| What is Hodgkin's Lymphoma? |
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Definition
| Painless cancerous enlargement of lymph nodes |
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Term
| What is non-Hodgkin's Lymphoma? |
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Definition
| More common form of lymphoma |
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Term
| What is a multiple myeloma? |
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Definition
| An increase in plasma cells w/ antibody overproduction |
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Term
|
Definition
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Term
| What is the leukemoid reaction? |
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Definition
| A high number of leukocytes that looks like, but is not leukemia |
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Term
|
Definition
| A rapid onset, rapidly fatal form of leukemia |
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Term
| What is chronic leukemia? |
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Definition
| Similar to acute, but of a gradual, slowly progressive course |
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Term
| What are some ocular effects of leukemia? (3) |
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Definition
| retinal or subconjunctival hemorrhage, papilledema, EOM weakness/paralysis |
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Term
| What are the 4 types of leukemia classification? |
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Definition
| Acute or Chronic (lymphocytic and meylocytic) |
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Term
| What is acute lymphocytic leukemia? |
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Definition
| Most common leukemia in children, peak occurrence of 4 years old |
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Term
| What is acute myelocytic leukemia? |
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Definition
| most common acute leukemia in adults, often from exposure (radiation, chemicals, chemotherapy) |
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Term
| What is chronic lymphocytic leukemia? |
|
Definition
| A form of leukemia that does not respond to treatment |
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Term
|
Definition
|
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Term
|
Definition
| Antimetabolite: Interferes with cell growth |
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Term
| What does Gleevec target? |
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Definition
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|
Term
| What are two important signs/sx of polycythemia vera? |
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Definition
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Term
| What causes neutrophilia? |
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Definition
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Term
| What causes eosinophilia? |
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Definition
| allergic rxn, infections, cancer |
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