Term
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Definition
| inhibits UDP-NAG to UDP NAM in peptidoglycan synthesis |
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Term
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Definition
| inhibits synthesis of alanine dipeptide, so can't connect to UDP NAm in peptidoglycan synthesis |
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Term
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Definition
| inhibits peptidoglycan synthesis, sp. can't put disaach to backbone chain; adds itself onto it, so can't add anymore! |
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Term
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Definition
| prevents release of P from lipid carrier undecaprenyl (neosporin action) |
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Term
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Definition
| Bactericidal!, non-growing cells,basic polypetides w/ fa chains disrupt phosphoethanolamine membranes |
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Term
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Definition
| bind to ergosterol, disrupt membrane, ie: nystatin & amphotericin |
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Term
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Definition
| inhibit syn of ergosterol, against fungi |
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Term
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Definition
| nalidixic acid, norfloxacin, & ciprofloxacin, inhibits nicking activity of DNA gyrase |
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Term
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Definition
| inhibit DNA synthesis, DNA gyrase |
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Term
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Definition
| dna synthesis inhibitor, DNA gyrase |
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Term
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Definition
| DNA synthesis inhibitor, DNA gyrase |
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Term
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Definition
| DNA synthesis inhibitor, DNA gyrase |
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Term
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Definition
| DNA synthesis inhibitor, not used clinically |
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Term
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Definition
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Term
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Definition
| DNA synthesis, inhibits folic acid synthesis, by mimicking PABA |
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Term
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Definition
| looks like DHF, inhibits Dihydrofolic reductase,req for purine and pyrididine synthesis. bacterocidial w/ sulfamide. |
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Term
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Definition
| TB drug, affects glycolysis, lipid synthesis, nucleic acid synthesis |
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Term
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Definition
TB drug, binds to RNA pol.
also for leprosy, and meningitis prophylaxis |
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Term
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Definition
| aminoglycosides, tetracycline, spectinomycin |
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Term
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Definition
| chloramphenicol, lindamycin, clindamycin, erythomycin (CLEan) |
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Term
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Definition
| blocks peptidyl transferase; 50S; toxicity |
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Term
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Definition
| Translation, 50S, blocks tRNA moving off P site; a macrolide |
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Term
| 1st generation bugs to kill |
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Definition
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Term
| Klebsiella pneumonia location and causes? |
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Definition
| usually in GI tract, causes respiratory and UTIs in hospital, severe lobar pneumonia in diabetics, alcholics, COPD patients, bloody currant jelly sputum |
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Term
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Definition
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Term
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Definition
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Term
| 2nd gen cephalosporin coverage |
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Definition
M.HenPeck
M = Moraxella catarrhis |
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Term
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Definition
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Term
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Definition
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Term
| Moraxella catarrhalis causes |
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Definition
| otitis media in children,sinusitis, lower respiratory infections, 2nd cause of COPD exacerbations |
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Term
| what call kill Bacteroides fragilis? |
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Definition
| Chloramphenicol, 2nd ge. Cephamycins (ie: Cefoxitin IV/IM) |
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Term
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Definition
| IV/IM, 2nd gen cephamycin, kills anaerobes!! |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| antipsuedo. IV/IM, 3rd gen |
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Term
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Definition
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Term
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Definition
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Term
| what are 3rd gen cephalosporins good treating for? |
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Definition
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Term
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Definition
| 4th gen cephalosporin, ORAL! |
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Term
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Definition
| oral, carbacephem-beta lactam, treat like 2nd cephalosporin to treat respiratory infections |
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Term
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Definition
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Term
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Definition
| combine w/ imipenem, inhibits DHP, found on brush border of kidney that hydrolyzes beta lactam ring |
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Term
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Definition
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