Term
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Definition
| live attenuated varicella vaccine, can be used for post-exposure prophylaxis, one injection for children under 12, two injections for people over 13 |
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Term
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Definition
| live attenuated varicella vaccine, for prevention of zoster in those over 60 years |
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Term
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Definition
| guanine analogue that requires viral thymidine kinase for activation, treatment for VZV, HSV |
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Term
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Definition
| treatment of herpes simplex keratoconjunctivitis, neurotoxicity, requires large volumes of fluid for administration, bone marrow suppression |
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Term
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Definition
| orally bioavailable drug with same action as guanine analogues, treatment for VZV and HSV |
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Term
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Definition
| prodrug of penciclovir with similar action as guanine analogues, oral formulation, approved treatment for zoster only |
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Term
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Definition
| structurally similar to guanine analogues, competitively inhibits deoxyguanosine triphosphate into DNA by viral DNA polymerase, for treatment of CMV |
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Term
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Definition
| prodrug of Ganciclovir, used for long term treatment of CMV |
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Term
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Definition
| inorganic pyrophosphate analogues, inhibits DNA polymerase by blocking pyrophosphate binding site, only available in IV formulation, high renal toxicity, chelates divalent metal ions, active against CMV, HSV, influenza, HBV, HIV |
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Term
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Definition
| cytosine analogue, significant renal toxicity, very long half life, used to treat resistant CMV |
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Term
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Definition
| live attenuated vaccine for healthy, non-pregnant persons from 2 to 49 for the prevention of influenza, contains 2 A strains and one B strain |
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Term
| Injected influenza vaccine |
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Definition
| treatment inactivated vaccine for anyone over 6 months old for prevention of influenza, contains 2 A strains and one B strain |
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Term
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Definition
| active against influenza A, inhibits M2 protein and inhibits viral membrane fusion |
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Term
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Definition
| inhibits neuraminidase of influenza A and B, an inhaled therapy |
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Term
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Definition
| inhibits neuraminidase of influenza A and B, an oral therapy that may cause psychiatric problems |
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Term
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Definition
| HPV4 vaccine that protects against cervical cancer and genital warts, recommended for girls and boys |
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Term
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Definition
| HPV2 vaccine that protects against cervical cancer but not genital warts, recommended for girls and young women |
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Term
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Definition
| HAV vaccine, for travelers and post exposure prophylaxis, administered in 2 doses |
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Term
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Definition
| HBV vaccine, for everyone, administered in 3 doses |
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Term
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Definition
| increases natural killer and cytotoxic T cell activity, three injections a week for 6-12 months, given as treatment for HBV, can cause psych symptoms and flu like symptoms |
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Term
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Definition
| nucleoside analogue that competitively inhibits reverse transcriptase, used for HBV and HIV infection |
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Term
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Definition
| nucleotide analogue that inhibits HBV reverse transcriptase |
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Term
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Definition
| nucleoside analogue that is good for resistant HBV strains, may cause dizziness, headache, lethargy, GI symptoms and photosensitivity |
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Term
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Definition
| thymidine nucleoside analogue for HBV treatment, may cause elevated CPK and muscle weakness |
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Term
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Definition
| nucleotide to treat HBV that may cause HIV resistance in coinfected patients |
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Term
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Definition
| for treatment of hepatitis C in combination with pegylated interferon alpha, but may cause hemolytic anemia and abnormal fetal development |
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Term
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Definition
| increases natural killer and cytotoxic T cell activity, one injection a week for 6-12 months, given as treatment for HBV, can cause psych symptoms and flu like symptoms |
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Term
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Definition
| NS3/4A protease inhibitor for HCV, may cause skin rash |
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Term
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Definition
| NS3/4A protease inhibitor for HCV, may cause anemia |
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Term
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Definition
| nucleoside reverse transcriptase inhibitor. Side effects include peripheral neuropathy |
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Term
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Definition
| nucleoside reverse transcriptase inhibitor. Potentially fatal hypersensitivity reaction with HLAB5701 |
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Term
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Definition
| non-nucleoside reverse transcriptase inhibitor that causes severe hepatotoxicity |
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Term
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Definition
| non-nucleoside reverse transcriptase inhibitor that causes psychiatric symptoms and is teratogenic |
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Term
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Definition
| HIV protease inhibitor, combination lopinavir and ritonavir, side effects include nausea, vomiting, diarrhea |
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Term
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Definition
| HIV protease inhibitor, causes asymptomatic hyperbilirubinemia |
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Term
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Definition
| HIV protease inhibitor, causes severe hepatitis |
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Term
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Definition
| HIV protease inhibitor, can cause rash |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| inhibits HIV1 integrase, side effects include diarrhea, nausea and fatigue |
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Term
| Nucleoside reverse transcriptase inhibitors |
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Definition
| Class of drugs associated with potentially fatal lactic acidosis with hepatic steatosis, inhibits HIV via early chain termination |
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Term
| Non-nucleoside reverse transcriptase inhibitors |
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Definition
| Class of drugs associated with rash and CYP affects, noncompetitive inhibitors of reverse transcriptase |
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Term
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Definition
| Class of drugs associated with GI symptoms, lipodystrophy, hepatotoxicity, and inhibits CYP3A |
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Term
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Definition
| Class of drugs that block chemokine receptors on immune cells |
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