Term
| What is the mechanism of action of Immune Globulin? |
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Definition
Passive Immunity increased.
Prevention of infectious diseases in susceptible individuals. |
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Term
| What are the indications of use for Immune Globulin? |
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Definition
Prevention of measles and hepatitis A.
Prophylactic use for prevention of measles and hepatitis B. |
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Term
| What are the Main Toxicities of Immune Globulin? |
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Definition
| Mild Toxicities- ingredients of formulations. |
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Term
| What is the mechanism of action for Rabies Immune Globulin? |
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Definition
| Antibody neutralizes virus-inhibits pathogenesis. |
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Term
| What is the indication for use of Rabies Immune Globulin? |
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Definition
| Passive Immunity to rabies virus. |
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Term
| What are the main toxicities of the rabies immune globulin? |
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Definition
Local tenderness and stifness.
Systemic anaphylaxis after IV administration. |
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Term
| What is the mechanism of action of Varicella-Zoster immune globulin? |
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Definition
| Antibody neutralizes varicella-zoster virues-inhibits pathogenesis. |
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Term
| What is the indication for use of varicella-zoster immune globulin? |
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Definition
| Passive immunity to varicella and herpes zoster. |
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Term
| What are the main toxicities of the Varicella-zoster immune globulin? |
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Definition
Local tenderness and irritation.
Systemic anaphylaxis after IV administration. |
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Term
| What is the mechanism of action for the Hepatitis B Immune Globulin? |
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Definition
| Antibody neutralizes the hepatitis B virus. |
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Term
| What is the indication for use of the Hepatitis B immune globulin? |
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Definition
| Passive Immunity to hepatitis B. |
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Term
| What are the main toxicities of the Hepatitis B immune globulin? |
|
Definition
Local tenderness and stiffness.
Anaphylaxis after IV administration. |
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Term
| What is the mechanism of action of amantadine? |
|
Definition
| Blocks penetration and uncoating of virus. |
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Term
| What is the indication for use of amantadine? |
|
Definition
|
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Term
| What are the main toxicities of amantadine? |
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Definition
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Term
| What is the mechanism of action of Ribavirin? |
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Definition
| DNA and RNA synthesis inhibition. |
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Term
| What are the indications of use for ribavirin? |
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Definition
Respiratory Syncytial Virus
Hepatitis C Virus (In combination with interferon alpha) |
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Term
| What are the main toxicities of Ribavirin? |
|
Definition
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Term
| What is the mechanism of action of Zanamivir? |
|
Definition
|
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Term
| What are the indications for use of Zanamivir? |
|
Definition
|
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Term
| What are the main toxicities of Zanamivir? |
|
Definition
| Nasal and throat discomfort. |
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Term
| What is the mechanism of action of oseltamivir? |
|
Definition
|
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Term
| What are the indications for use of Oseltamivir? |
|
Definition
|
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Term
| What are the main toxicities of Oseltamivir? |
|
Definition
| Nausea and Vomiting and Headache. |
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Term
| What is the mechanism of action of Trifluridine? |
|
Definition
| DNA synthesis inhibition. (viral and cellular) |
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Term
| What is the indication for use of Trifluridine? |
|
Definition
| Herpes Simplex Keratitis. |
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Term
| What are the main toxicities of Trifluridine? |
|
Definition
Teratogenic.
Visual Haze. |
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Term
| What is the mechanism of action of IFN-a-2a? |
|
Definition
| Viral Protein and Replication Inhibition. |
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Term
| What is the indication for use of IFN-a-2a? |
|
Definition
Genital and Anal Warts.
Hepatitis B
Hepatitis C and Ribavirin. |
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Term
| What are the main toxicities of IFN-a-2a? |
|
Definition
Flu Like Syndrome.
Myalgia
Transient Hematologic. |
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Term
| What is the mechanism of action of Acyclovir? |
|
Definition
| DNA synthesis inhibition. |
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Term
| What are the indications of use for Acyclovir? |
|
Definition
Mucosal, Cutaneous, or Systemic Herpes simplex
Genital Herpes
Varicella Zoster |
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Term
| What are the main toxicities for Acyclovir? |
|
Definition
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Term
| What is the mechanism of action for Gancyclovir? |
|
Definition
| DNA synthesis inhibition. |
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Term
| What is the indication for Gancyclovir? |
|
Definition
| Cytomegalovirus Retinitis |
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|
Term
| What are the main toxicities of Gancyclovir? |
|
Definition
Teratogenic.
Myelosuppresion.
Neutropenia. |
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Term
| What is the mechanism of action of Foscarnet? |
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Definition
| DNA synthesis inhibition. |
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Term
| What are the indications for foscarnet? |
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Definition
| Cytomegalovirus retinitis in AIDS patients. |
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Term
| What are the main toxicities of Foscarnet? |
|
Definition
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