Term
| Phenytoin indications (2) |
|
Definition
|
|
Term
| Phenytoin adverse effects (6) |
|
Definition
o CNS effects
o *Gingival hyperplasia *
o Osteoporosis
o *Hirsutism*
o Megaloblastic anemia
o Peripheral neuropathy |
|
|
Term
| Carbamazepine adverse effects (5) |
|
Definition
o Aplastic anemia (BBW)
o Agrunolocytosis (BBW)
o Hepatotoxicity
o Hyponatrimia
o Rash (SJS) |
|
|
Term
| Carbamazepine indications (2) |
|
Definition
|
|
Term
| Valproic Acid indications (4) |
|
Definition
|
|
Term
| Valproic acid adverse effects (7) |
|
Definition
o Hepatotoxicity (BBW)
o Pancreatis (BBW)
o Teratogenicity (BBW)
o Encephalopathy
o Alopecia
o PCOS
o Weight gain |
|
|
Term
| Oxcarbazepine indication (1) |
|
Definition
|
|
Term
| Oxcarbazepine adverse effects (2) |
|
Definition
|
|
Term
| Felbamate indications (3) |
|
Definition
Partial
Atonic (patients with lennox-gastaut)
Refractory epilepsy |
|
|
Term
| Felbamate adverse effects |
|
Definition
Weight loss (anorexia)
Aplastic anemia (BBW)
Hepatotoxicity (BBW) |
|
|
Term
| Gabapentin indication (1) |
|
Definition
|
|
Term
| Gabapentin adverse effects (2) |
|
Definition
Weight gain with chronic use
Somnolence |
|
|
Term
| Lamotrigine indications (3) |
|
Definition
Partial (mono or adjunct)
Adjunct for Lennox-Gastaut)
Adjunct for GTC |
|
|
Term
| Lamotrigine adverse effects (2) |
|
Definition
Rash (SJS) BBW
*Toxic epidermal necrosis* |
|
|
Term
| Levetiracetam indications (3) |
|
Definition
Adjunct for:
Partial (>4yo)
JME (>12yo)
GTC (>6yo) |
|
|
Term
| Levetiracetam adverse effects (3) |
|
Definition
asthenias
CNS effects
Somnolence |
|
|
Term
| Topiramate indications (3) |
|
Definition
Mono or adj for:
Partial
GTC
Adjunct for:
Lennox-Gastaut (>2yo) |
|
|
Term
| Topiramate adverse effects (7) |
|
Definition
o *Cognitive slowing*
o *Renal calculi*
o Weight loss
o Metabolic acidosis
o Kidney stones
o Paresthesia
o Attentional deficit (in children, AE might be confused for ADD) |
|
|
Term
| Zonisamide indication (1) |
|
Definition
| Adjunct for partial (>16yo) |
|
|
Term
| Zonisamide adverse effects (3) |
|
Definition
o Oligohydrosis (in children)
o Weight loss
o Renal calculi |
|
|
Term
| Tiagabine indications (1) |
|
Definition
| Adjunct for partial (>12 year old) |
|
|
Term
| Tiagabine adverse effects (3) |
|
Definition
Tremor
Asthenia
Nervousness |
|
|
Term
| Pregabalin indications (1) |
|
Definition
|
|
Term
| Prgabalin adverse effects (3) |
|
Definition
Weight gain
Somnolence
Dizziness |
|
|
Term
| Clonazepam indications (4) |
|
Definition
Myoclonic
Akinetic
Lennox-Gastaut
Refractory absence seizures |
|
|
Term
| Clonazepam adverse effects (3) |
|
Definition
o Mild impairment of cognition and motor skills
o Behavioral changes in children
o Must taper |
|
|
Term
| Lacosamide indications (1) |
|
Definition
| Adjunct for partial onset (>17 year old) |
|
|
Term
| Lacosamide adverse effects (4) |
|
Definition
Diplopia
Headache
Dizziness
Nausea |
|
|
Term
| Rufinamide indications (1) |
|
Definition
| adjunct for Lennox-Gastaut |
|
|
Term
| Ruvinamide adverse effects (3) |
|
Definition
Coordination abnormalities
Gait disturbances
Ataxia |
|
|
Term
| Vigabatrin indications (2) |
|
Definition
Infantile spasms
Adjunct for refractory complex partial |
|
|
Term
| Vigabatrin adverse effects (4) |
|
Definition
| o Vision loss (SHARE program) o Anemia o Peripheral neuropathy o MRI abnormalities (normalize when D/C drug) |
|
|
Term
| Which drugs do NOT carry a risk for suicide? |
|
Definition
|
|
Term
| Which drug has almost no major drug interactions? |
|
Definition
|
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