Term
| What are the positive symptoms of schizophrenia |
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Definition
| Deluxions, Hallucinations, disorganized speech, and catatonic behavior |
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Term
| What are the negative symptoms of schizophrenia |
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Definition
| Affective flattening, alogia, and avolition |
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Term
| Which parts of the brain are affected in schizohrenia? |
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Definition
| Mesocortical and mesolimbic |
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Term
| Which part of the brain causes positive symtoms of schizophrenia? |
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Definition
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Term
| What do anytipsychotic drugs end in? |
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Definition
| ~azine or ~thixene or ~peridol. Also Loxapine, Molindone, and Pimozide |
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|
Term
| Which receptor do typical antipsychotics work on? |
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Definition
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Term
| What do atypical antipsychotics end in? |
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Definition
| ~idone or ~apine, also Aripiprazole |
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Term
| True or false: typical antipsychotics are better at controlling the positive effects of schizophrenia |
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Definition
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Term
| Which of the following is NOT a theory of how Antipsychotic agents work? A: They antagonize 5-HT2 AND D2, B: They selectively inhibit D2 AND D4, C: They Inibit D4 but agonize 5-HT-2 or D They rapidly dissociate from D2 receptrs |
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Definition
| C. They do not agonize 5-HT-2 |
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Term
| Which receptor causes extrapyramidal effects? |
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Definition
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Term
| What effects are collectively known as extrapyramidal effects? |
|
Definition
| Acute dystonia, akatheisia, Parkinsonism, Rabbit Syndrome, Tardive dyskinesia |
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|
Term
| When does Acute dystonia show up? |
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Definition
|
|
Term
| when does Akathisia show up? |
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Definition
|
|
Term
| When does Parkinsonism show up? |
|
Definition
|
|
Term
| When does Rabbit syndrome show up? |
|
Definition
| after months or years of treatment |
|
|
Term
| When does Tardive dyskinesia show up? |
|
Definition
| after months or years of treatment |
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|
Term
| Which atypical antipsychotic has the most EPS effect? |
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Definition
|
|
Term
| Which antipsychotic has the LEAST side effects? |
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Definition
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Term
| What are the typical antipsychotic drugs? |
|
Definition
| Haloperidol, Fluphenazine, Thiothixine, Trifuoperazine, Chloropromazine, Mesoridazine, Thioridazine. HAL Flew Thith Train. Catch me the rest |
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|
Term
| What are the atypical antipsychotic drugs? |
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Definition
| Risperidone, Ziprasidone, Clozapine, Aripiprazole, Quetiapine, Olanzapine. Rip, Zip, ClAP. Quiet! Olan. |
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Term
| Based on the order given in our chart, which drugs have the most EPS effects? |
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Definition
| Highest at top, lowest at bottom. Halo to Thioridazine |
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|
Term
| According to our chart, which atypical drugs have the most EPS? |
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Definition
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|
Term
| According to our chart, which typical drugs are most sedating? |
|
Definition
| The bottom ones are. Chloro, Meso, and Thio |
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|
Term
| According to our chart, which aytpical drugs are the most sedating? |
|
Definition
| It makes a suspension bridge. Clozapine and Quetiapine are the worst. Olan and Arip are the best |
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|
Term
| According to our chart, which typical drugs have the most hypotensive effects? |
|
Definition
| Bottom Heavy. Chloro, meso, and Tioridiazine |
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|
Term
| Which atypical drugs have the most hyptensive effects? |
|
Definition
| All are pretty equal except for Aripiprazole. |
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|
Term
| Which drugs can cause QT prolongation? |
|
Definition
| Thioridazine, Mesoridazine, Halopiriidol, and Ziprasidone. QT prolongation can kill you. Hail Mary, Zip the rest. |
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|
Term
| Which drug is associated with agranulocytosis? |
|
Definition
|
|
Term
| Which drugs make you gain weight? |
|
Definition
| Clozapine and Olanzapine. Cl olan (clown) around, and gain weight |
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|
Term
| Which drugs are NOT associated with weight lost |
|
Definition
| Aripiprazole and ziprasidone. They make you zipped and ripped. |
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|
Term
| What is an unusal side effect of antipsychotics? |
|
Definition
| hyperprolatinemia. You make more prolactin on old drugs and risperdone |
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|
Term
| Which drug causes poikilothermic effect? |
|
Definition
| Chlorpromazine. (eleveated body temperature) |
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|
Term
| Which OTHER drugs cause QT elongatoin? |
|
Definition
| Sotalol, Dofetiilide, Quinidine, Quinolones, Macrolides. So Don't Mack on Quin Quin |
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|
Term
| What are the two most important functions of the Noradrenergic system? |
|
Definition
| Stress responses and pain control |
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|
Term
| Which receptors increase cAMP? |
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Definition
|
|
Term
| Which receptors decrease cAMP? |
|
Definition
|
|
Term
| Which receptors increase IP3? |
|
Definition
|
|
Term
| Which Receptrs are ligand gated ion channels? |
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Definition
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|
Term
| How long must depression go on to be considered major? |
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Definition
|
|
Term
| What does typical depression respond well to? |
|
Definition
|
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Term
| True or false: Patients with atypical depression respond well to SSRI therapy. |
|
Definition
| False. MAOIs are best, but that's not considered firstline therapy. |
|
|
Term
| What do you use for atypical depression? |
|
Definition
| buproprion, vanlafaxine, and mehtylphenadate |
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|
Term
| What is the most severe type of depression? |
|
Definition
|
|
Term
| What do you give a person with melancholic depression |
|
Definition
| SSRIs, mirtazapine, or maybe TCAs |
|
|
Term
| How long until MAOIs start to work? |
|
Definition
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|
Term
| What is the effect of stimulating auto receptors? |
|
Definition
| They inhibit postsynaptic signaling |
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|
Term
| What is the net effect of antidepressant drug therapy? |
|
Definition
| Even though autoreceptors are activated, post-synaptic signaling is increased. |
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|
Term
| What is the longterm effect of antidepressant therapy? |
|
Definition
| Auto receptors are down regulated and post-synaptic signaling goes way up |
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