Term
|
Definition
| prevents polymerization of heme |
|
|
Term
|
Definition
| acute attacks of p falciparum and nonfalciparum malaria |
|
|
Term
|
Definition
| blocks DNA replication by binding to DNA |
|
|
Term
|
Definition
| chloroquine resistant falciparum |
|
|
Term
|
Definition
| cinchonism -GI distress, headache, vertigo, blurred vision, tinnitus |
|
|
Term
|
Definition
|
|
Term
| clinical use of primaquine |
|
Definition
| liver stage of vivax and ovale |
|
|
Term
|
Definition
| blocks folic acid synthesis |
|
|
Term
| clinical use of sulfonamide |
|
Definition
|
|
Term
|
Definition
| diloxanide, iodoquinol, paromomycin |
|
|
Term
| which statement about antiprotozoal drugs is accurate |
|
Definition
| a combination of primaquine and clindamycin is an alternative drug regimen for PCP |
|
|
Term
| which antimalarial drug causes a dose-dependent toxic state that includes flushed and sweaty skin, dizziness, nausea, diarrhea, tinnitus, blurred vision, and impaired hearing |
|
Definition
|
|
Term
| plasmodial resistance to chloroquine is due to |
|
Definition
| decreased accumulation of the drug in the food vacuole |
|
|
Term
| prophylaxis for chloroquine-resistant falciparum is |
|
Definition
|
|
Term
| which drug should be used for oral tx of acute attack of vivax |
|
Definition
|
|
Term
| which drug should be given later to eradicate schizonts and latent hypnozoites in the patient's liver |
|
Definition
|
|
Term
| preferred tx that he should have received for initial symptoms of e histolytica |
|
Definition
| metronidazole plus diloxanide furoate |
|
|
Term
| the drug regimen most likely to be effective in treating severe extraintestinal disease in this patient is |
|
Definition
| metronidazole plus diloxanide furoate |
|
|
Term
| this drug is the antimalarial agent most commonly associated w/ causing an acute hemolytic rxn in pts w/ G6PD deficiency |
|
Definition
|
|
Term
| drinking water w/o purification tx w/ |
|
Definition
|
|
Term
| this drug can clear trypanosomes from the blood and lymph nodes and is active in the late CNS stages of african sleeping sickness |
|
Definition
|
|
Term
| metronidazole is not effective in the tx of |
|
Definition
|
|
Term
| which drug is recommended as the DOC for oral tx of uncomplicated malaria caused by chloroquine-resistant falciparum |
|
Definition
|
|
Term
| side effect of chloroquine |
|
Definition
| hemolysis in G6PD deficiency, bullseye retina |
|
|
Term
| side effect of metronidazole |
|
Definition
| seizures, ataxia, dizziness, disulfiram-like rxn |
|
|
Term
| side effect of primaquine |
|
Definition
| hemolysis in pts w/ G6PD deficiency |
|
|
