Term
Antifungals
2 groups covered |
|
Definition
| Superficial mycosis and systemic mycosis (most dangerous) |
|
|
Term
| Amphotericin B is the DOC for: |
|
Definition
Systemic infections but highly toxic
Only used for progressive and fatal infections |
|
|
Term
|
Definition
|
|
Term
| Amphotericin B is detected for: |
|
Definition
| Up to a year after withdrawal |
|
|
Term
| Amphotericin B adverse effects |
|
Definition
| Nephrotoxicity- check kidney fxn every 3-4 days |
|
|
Term
|
Definition
Inhibits CYP 450 enzyme
Drug levels would Inc bc nothing is getting metabolized
- dec levels of those drugs
- cisapride, pimozide, dofetilide, quinidine |
|
|
Term
Flucytosine used for:
Used in combo with: |
|
Definition
Serious infections if candida and crytococcus neoformans
Amphotericin B |
|
|
Term
| Flucytosine adverse effects |
|
Definition
Bone marrow suppression
Monitor renal fxn |
|
|
Term
|
Definition
Tinea pedis- athletes foot
Tinea corporis- ringworm
tinea cruris- jock itch
Tinea capitus- griseofulvin |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Ganciclovir adverse effects |
|
Definition
Teratogenic
Can cause harm to baby if pregnant |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Interferon alpha used for: |
|
Definition
|
|
Term
Interferon alpha
Used for how long? |
|
Definition
| 12 months of tx but usually relapse after tx withdrawal |
|
|
Term
| Interferon alpha adverse effects |
|
Definition
|
|
Term
| Hep B transmission through: |
|
Definition
|
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