Term
| what does it mean to say that an antibiotic is bacteriostatic? |
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Definition
| it reversible inhibits metabolic processes of bacteria, (stops growth) |
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Term
| what does it mean to say that a drug has a narrow spectrum of activity? extended? broad? |
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Definition
| narrow spectrum antibiotics will only act on a single or limited group of microbes. extended spectrum antibiotics can be modified to be effective against gram + and gram – organisms. broad spectrum antibiotics are active against a wide range of bacteria |
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Term
| what is the difference between antibiotic susceptible and resistant bacteria? |
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Definition
susceptible: in vitro and in vivo susceptibility means the growth can be inhibited or killed by antibiotic.
resistant: in presence of antibiotic the organism will continue to grow and live |
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Term
| what is the first line of antibiotics to be considered? |
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Definition
| antibiotics that inhibit cell wall synthesis, b/c peptidoglycan can't be found in eukaryotic cells. |
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Term
| why might oral routes of administration be chosen? |
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Definition
| less costly and few complications? |
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Term
| why might paraenteral, (IV) administration be considered? |
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Definition
| if the drug is poorly adsorbed from the intestinal tract, if the pt has disease that would impair absorption, or if the pt is critically ill/suffers from menigitis,(to get through the blood brain barrier) or endocarditis |
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Term
| Trimethoprim/Sulfamethoxazole |
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