Term
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Definition
| Mood stabilizer, first line for bipolar/depression/mania, inhibits suicidal behavior, serious ADRs (GI, neuro, metabolic, derm), teratogen, serious end-organ effects |
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Term
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Definition
| Anticonvulsant mood stabilizer, boosts GABA, inhibits Glu (modulates Ca/Na channels), first line for rapid cycling/dysphoric mania, ADRs (GI, increased appetite, hair loss, tremor), serious ADRs (PSOS,pancreatitis) |
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Term
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Definition
| Anticonvulsant mood stabilizer, enhances GABA inhibition (modulates Na/K pump), used in mixed mania/rapid cycling BPD, ADRs: induces P450 (serious drug-drug interactions) |
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Term
| Common serious problems with mood stabilizers |
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Definition
| Teratogens, cognitive dulling, overdose, drug-drug interactions, thrombocytopenia, hepatotoxicity, GI, nausea, tremor, routine blood testing |
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Term
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Definition
| Anticonvulsant mood stabilizer, metabolite of carbamezapine=>further downstream, fewer drug-drug/toxicities, does NOT require blood monitoring, may not work? |
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Term
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Definition
| Anticonvulsant mood stabilizer, "Prozac of mood stabilizers", BPD spectrum conditions, depressive BPD, Serious ADR: rash(8%)=>Stevens-Johnson Syndrome(0.08%) |
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Term
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Definition
| Atypical antipsychotics, typical antipsychotics, omega-3 fatty acids, Calcium channel blockers, benzodiazepines |
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Term
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Definition
| Anticonvulsant, GABA analogue, decrease Glu, not effective as monotherapy, anxiolytic, analgesic, well tolerated |
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Term
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Definition
| Anticonvulsant, inhibits Na/Ca channels, -Glu, +GABA, not effective as monotherapy, weight loss, sedation, cognitive dulling |
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Term
| Medications for anxiety disorders |
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Definition
| Antidepressants (SSRI, TCA, MAOI), atypical antipsychotics, beta-blockers, anticonvulsants, antihistamines |
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Term
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Definition
| Antidepressants (TCA), atypical antipsychotics, antihistamines, anticonvulsants |
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Term
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Definition
| Anxiolytic, GABA channel allosteric activator, addictive, depress all levels of CNS=>narrow therapeutic index, increases DURATION of channel opening |
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Term
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Definition
| Anxiolytic, GABA channel allosteric activator, safer, more efficacious, specific to anxiety, no respiratory or cardiac effects, less addictive, less lethal in overdose, 30 benzos available, increases FREQUENCY of channel opening |
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Term
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Definition
| NOT chemically similar, meprobamate, chloral hydrate, methaqualone, more dangerous, more abuse potential (shorter duration of effects) |
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