Term
|
Definition
given to kids born with HIV
cytidine analog |
|
|
Term
|
Definition
|
|
Term
|
Definition
prevent cleavage of GAG-POL on HIV
also used for HCV |
|
|
Term
|
Definition
| protease inhibitor useful for protease ihibitor resistant strains of HIV because it is a NON-PEPTIDE |
|
|
Term
|
Definition
| contraindicated with Rifampin |
|
|
Term
|
Definition
binds to gp41
prevents fusion to cell membrane |
|
|
Term
|
Definition
prevents HIV entry into cell
CCR5 (not cxcr4) |
|
|
Term
|
Definition
|
|
Term
| Reverse transcriptase inhibitors |
|
Definition
|
|
Term
Lamivudine and Entecavir
(NRTIs) |
|
Definition
| Tx HBV (DNA virus that uses RT) |
|
|
Term
|
Definition
|
|
Term
| Boceprevir and Telaprevir |
|
Definition
| protease inhibitors tx HCV |
|
|
Term
|
Definition
inhibits viral DNA polymerase
needs cellular thymidine kinase
tx: Herpes, VZV, CMV |
|
|
Term
| Doxuridine and Trifluridine |
|
Definition
Inhibits DNA polymerase
treats HSV keratitis, and other ocular infections |
|
|
Term
|
Definition
| CMV and herpes tx with acyclovir resistance |
|
|
Term
|
Definition
nota a base analog!
inhibits viral pyrophosphate binding at viral DNA polymerase |
|
|
Term
|
Definition
nucloeTide
tx HSV1 HSV2 and CMV retinitis |
|
|
Term
|
Definition
tx CMV
inhibits virus by using antisense
mechanism by micro RNA. |
|
|
Term
| Amantadine and Rimantadine |
|
Definition
Hemagglutin inhibitors
inhibit viral entry
influenza A only |
|
|
Term
| Zanamivir and Oseltamivir |
|
Definition
neuraminidase inhibitors
prevent viral exit from cells
influenze A and B |
|
|
Term
|
Definition
| upregulate MHC 1 expression during viral infection |
|
|
Term
|
Definition
| only herpes tx not base analog |
|
|
Term
|
Definition
monoclonal antibody highly specific for RSV.
must be administered IM.
far superior drug tx RSV (better than Ribavirin) |
|
|
Term
|
Definition
| can cause bone marrow suppression |
|
|
Term
|
Definition
| low resistance compared to other NRTIs |
|
|
