Term
|
Definition
chloropromazine thioridazine fluphenazine |
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Term
|
Definition
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|
Term
| what are the most potent anti-psychotic |
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Definition
butyrophenones (haloperidol) piperazine (fluphenazine) |
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Term
| anti-psychotics w/greater extra pyramidal symptoms |
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Definition
|
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Term
| which anti-psychs have greater alpha blocking activity |
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Definition
|
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Term
|
Definition
| lower potency has greater effects |
|
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Term
| anti-psych that can stop hiccups |
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Definition
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|
Term
| mech of action for anti-psychs |
|
Definition
| blocking of dopamine in mesolimbic/cortical system |
|
|
Term
| where do the extra pyramidal side effects come from? |
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Definition
|
|
Term
| which dopa receptor is blocked |
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Definition
|
|
Term
| which have active metabolites |
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Definition
| aliphatic and piperidine phenothiazines |
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|
Term
| early motor fluctuations? |
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Definition
dystonia- 1-5 days akathisia- 5-60 days parkinson- 5-30 days
treat w/anticholinergics |
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Term
|
Definition
tardive dyskinesia peri oral tremor |
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|
Term
| endocrine problems of anti-psych |
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Definition
hyperprolactinemia decreased GnRH release |
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|
Term
| what is best choic in epileptic patient? |
|
Definition
piperazine phenothiazines fluphenazines |
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|
Term
| treatment for neuroleptic malignant syndrome |
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Definition
|
|
Term
| Adverse autonomic effects of anti-psychs |
|
Definition
lower potency especially
muscarinic blockade (dry, constipated...) |
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|
Term
| what are high potency antipsychs contra'd in |
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Definition
| pts w/pre-existing pyramidal disorders |
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