Term
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Definition
| Folate antagonist-PABA Analogs-Dihydropteroate Synthetase Inhibitors. inhibit folate synthetis, Newer |
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Term
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Definition
| Folate antagonist-PABA Analogs-Dihydropteroate Synthetase Inhibitors. GI, does not get absorbed systemically. Chronic bowel disease |
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Term
| Silver sulfadiazine (Silvadene) |
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Definition
| Folate antagonist-PABA Analogs-Dihydropteroate Synthetase Inhibitors. Topical. for burns |
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Term
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Definition
| Folate antagonist-PABA Analogs-Dihydropteroate Synthetase Inhibitors. Newer |
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Term
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Definition
| Folate antagonist-PABA Analogs-Dihydropteroate Synthetase Inhibitors. Opthalamic |
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Term
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Definition
| Folate antagonist-DHF reductase inhibitor, more potent than sulfa drugs, broader spectrum, less resistance |
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Term
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Definition
| Folate antagonist-DHF reductase inhibitor, more potent than sulfa drugs |
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Term
| Trimethoprim + sulfamethoxazole |
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Definition
| Folate antagonist-Cotrimoxazole (combination). synergism- inhibition of 2 sequential steps in synthesis of tetrahydrofolic acid synthesis, selective inhibition of bacterial dihydrofolic acid reductace. |
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Term
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Definition
| bacteriostatic, broad spectrum, active against gm + & -. UTI, chamydia, pneumocystis, nocardia |
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Term
| Crystalluria, nephrotoxicity; hypersensitivity, rashes, photosensitivity, angioedema; stevens-johnson syndrome; hemolytic anemia, granulocytopenia, thrombocytopenia. CI preggo |
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Definition
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Term
| folate deficiency, megaloblastic anemia, leukopenia, granylocytopenia, |
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Definition
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Term
| Sulfadiazine + Pyrimethamine |
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Definition
| Folate antagonist-(combination. DOC toxoplasmosis, chloroquine-resistant malaria. |
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Term
| skin, GI, megaloblastic anemia, G6PD deficiency, HIV, drug interactions |
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Definition
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Term
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Definition
| Formaldehyde- Sulfonamides CI with the drug- condense |
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