Term
| what are the two tricyclics |
|
Definition
| nortriptyline and amitryptiline |
|
|
Term
|
Definition
work w/lithium for bipolar
sleep disorders
chronic neuropathic pain |
|
|
Term
| Mech of action for Tricyclic |
|
Definition
nortriptyline- greater of norep uptake
amitryp- inhibit serotonin more |
|
|
Term
| adverse effects of tricyclics |
|
Definition
CNS: weight gain, reduced seizure threshold
ANS: muscarinic effect (amitryp has greater effect) **NOT use in narrow angle glaucoma**
alpha antag. activity (nor is greater) |
|
|
Term
| Coadministration with MAOIs causes |
|
Definition
|
|
Term
|
Definition
| Fluoxetine, Paroxetine, Setraline, and Citolapram |
|
|
Term
|
Definition
| panic anxiety and OCDisorders |
|
|
Term
|
Definition
|
|
Term
| This SSRI has B-adrenoceptor downregulation affects |
|
Definition
|
|
Term
| Half life of SSRIs longest to shortest |
|
Definition
| Citalopram>Sertraline>Paroxetine>fluoxetine |
|
|
Term
|
Definition
|
|
Term
| Major adverse effects of SSRIs |
|
Definition
anorgasmia in men and women
ejaculatory disturbance in men |
|
|
Term
| SSRI causing cardiace birth defect |
|
Definition
|
|
Term
| these two SSRIs inhibit CYP2D6 |
|
Definition
| fluoxetine and paroxetine |
|
|
Term
| This SSRI displaces warfarine and digoxin |
|
Definition
|
|
Term
|
Definition
| Venlafaxine and Duloxetine |
|
|
Term
| This drug is widely used in smoking cessation programs |
|
Definition
| Wellbutrin/Zyban-buproprion |
|
|
Term
| what should be taken into consideration w/Buproprion |
|
Definition
|
|
Term
| mech of action for trazodone |
|
Definition
| blocks reuptake of 5-HT, also NE |
|
|
Term
| adverse effects of buproprion |
|
Definition
contra'd in patients w/history of seizures
agitation |
|
|
Term
| Adverse effects of trazodone |
|
Definition
priapism (painful erection)
has use in prostate cancer |
|
|
Term
|
Definition
|
|
Term
|
Definition
| depression and narcolepsy |
|
|
Term
|
Definition
| increase CNS levels of norep, dopamine, and serotonin |
|
|
Term
|
Definition
insomnia
hyperthermia
convulsions |
|
|
Term
| comb of MAOI and what causes hypertensive crisis |
|
Definition
beer, wine, cheese, chicken liver
OTC
amphetamines |
|
|
