Term
|
Definition
| neutropenia, thrombocytopenia and pancytopenia |
|
|
Term
|
Definition
| fatigue, dizziness, fainting, low blood pressure, palpitations, enlarged spleen, yellowing of eyes, skin paleness, coldness, SOB, muscle weakness, changed stool color |
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Term
|
Definition
| level of anemai (Hgb, Hct), rapidity of change, co-morbidities |
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|
Term
|
Definition
| mesh-like network of ribasomal RNA which becomes visible with methylene blue |
|
|
Term
|
Definition
| mestrual blood loss, GI blood loss, pregnancy or poor iron absorption |
|
|
Term
|
Definition
| insufficient intake of iron |
|
|
Term
|
Definition
| blackstrap molasses, clams,raisin bran cereal, turkey (dark), red meat |
|
|
Term
| symptoms of B12 deficiency |
|
Definition
| yellow pallor, neuro-findings, sore-beefy tongue, anorexia, tachycardia, palpitations, cardiomyopathy, heart failure |
|
|
Term
| causes of folate deficiency |
|
Definition
| ETOH abuse, pregnancy, malabsorption/ inadequate intake and some drugs |
|
|
Term
| drugs causing folate deficiency |
|
Definition
| phenytoin, MTX and colchicine |
|
|
Term
|
Definition
| dyspnea/fatigue, dark urine, pale/jaundice, enlarged spleen, tachycardia/murmers |
|
|
Term
| most patients have no evidence of hemolysis until an event |
|
Definition
| infection, drug reaction (sulfa, anti-malarials, ASA, INH, or eating a lot of fava beans |
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Mean corpuscular volume (MCV) |
|
Definition
|
|
Term
|
Definition
| Folate or B12 deficiency, chronic liver disease, chronic alcoholism, cytotoxic medications |
|
|
Term
|
Definition
| Iron deficiency, alpha/beta thalassemia (minor) and chronic disease (usually normocytic) |
|
|
Term
|
Definition
| Increased in central clear area |
|
|
Term
|
Definition
| Iron deficient, anemia of chronic disease, alpha or beta thalassemia, decreased MCV |
|
|
Term
|
Definition
| B12 deficient, folic acid deficient, alcoholism, some cytotoxic drugs, ususally increased MCV |
|
|
Term
|
Definition
| Deformed broken cell, helmet cell, Burr cell, acanthpcyte, seen in mechanical valvular and hemolytic anemias |
|
|
Term
|
Definition
| 65% Hgb, 4% yoglobin, 30% ferritin, serum transferrin |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Determines the ability to absorb B12 form the GI tract (requires intrinsic factor) |
|
|
Term
|
Definition
| Suggests pernicious anemia |
|
|
Term
|
Definition
| H2 antag, metformin, gastrectomy, poor dietary intake (limited meat and milk) |
|
|
Term
|
Definition
| Looks like pernicious anemia but does not have neurologic symptoms |
|
|
Term
| Giving folic acid to pernicious anemia |
|
Definition
| Worsens neurologic symptoms |
|
|
Term
| Causes of folate deficiency |
|
Definition
| Alcoholism, preggers, phenytoin, colchicine, MTX, BCPs?, some small bowel diseases |
|
|
Term
|
Definition
|
|
Term
| DAT; Direct Coomb's (antiglobulin) test |
|
Definition
| Demonstrates presence of antibodies or complement on the surface of RBCs; hallmark of autoimmune hemolysis |
|
|
Term
|
Definition
| Increased total bilirubin and unconjugated |
|
|
Term
| Normal total bilirubin levels |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Used with suspected hemoglobinopathies and thalassimias |
|
|
Term
|
Definition
|
|
Term
| False positive guaiac test |
|
Definition
| Meat consumption and high dose vitamin C |
|
|
Term
| Myriad cause of pos guaiac test |
|
Definition
| Malignancy, Uv/diverticulitis, others |
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