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A wave of electrical excitation proportional to the magnitude of the stimulus that triggers it. The graded potential declines in magnitudes as it travels along a nerve fiber. Will fade with distance |
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An action potential is an all or nothing phenominon. Once initiated, it propagates without decrement along the nerve fiber. Action potentials are often used in long distance signaling in the nervous system Does not fade with time |
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| Absolute refractory period |
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| Cabbot get an action potential |
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| Relative refractory period |
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| The channels are still open (k+ is leaking out) making it harder to get an action potential but it is still possible |
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| Action potential depolarization |
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Definition
Inward movement of sodium via voltage-gate channels Channels will close spontaneously |
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| Action potential repolarizing |
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Outward movement of potassium via k+ volt age gated channels Gates close when resting potential is restored |
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The myelin sheath is zoomed by a neuroglial cell that is separately wrapped around a nerve fiber. In the Perphrial nervous system, the neuroglial cell is a Schwann cell |
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The myelin sheath is formed by a neuroglial cell that is separately wrapped around a nerve fiber. The boundaries between them Are nodes of ranvier |
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The myelin sheath is formed by a neuroglial cell that is separately wrapped around a nerve fiber. In the central nervous system the neuroglial cells are oligodendroglial cells |
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Pass nutrients between blood capillary and neurons. Provide physical support for neuron by wrapping around blood vessels and neurons to anchors them to blood vessels, guiding the formation of young neurons and adjust the chemical environment |
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"clean up crew" Phagocytes |
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Line the central canal of the brain and spinal cord Help circulate cerebral spinal fluid via cilia |
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The transport towards axon terminals They would move: some enzymes, mitochondria and some cytoskeletal parts |
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Carry things away from axon terminals Organelles for degradation would move this way Polio reaches the cell body as a motor neuron this way (potentially destroying the cell body) |
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Involved in our perception of the outside world Neves carrying information from the tissue to the central nervous system are sensory neurons Afferent |
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Neves carrying information away from the central nervous system to effectors are motor neurons Efferent |
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Happen between sensory neurons and motor neurons Have the ability to change the message a little |
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Electrical synapse happen at ? What direction? |
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Gap junctions Bidirectional |
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Chemical synapse happens where? Direction? |
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Neuromuscular junction Unidirectional |
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| Excitatory post-synaptic potential |
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| Inhibitory post synaptic potential |
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Petaining to ACh Vasodialator |
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Epinephrine and NOrpinephrine (vasoconstrictors) Dopamine GABA Saratonin |
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Associated with locomotion and reward in mammals Deficient in Parkinson's disease Adrenergic |
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Gamma amino butyric acid Inhibitory in vertebrates in central nervous system Adrenergic |
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At synapse involved in sleep, pain, food intake Adrenergic |
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Control centers for respiration, circulation, intestinal motility Mot ancient |
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All vertebrate except agnathans have this Maintains balance and coordinates skilled voluntary muscle activity |
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Forebrain Includes the thalamus, hypothalamus and epithalamus |
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Relay station for sensory input and motor output Involved in memory processing |
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Integrating centers for autonomic nervous system Regulates body temperature, food intake, water balance, biological rhythms Regulates the anterior puitary and produces oxytocin and ADH (anti diuretic hormone) |
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| Includes basal nuclei and cerebral cortex |
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| Coordination of slow, sustained movement |
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| Voluntary movement, sensory perception, thinking, memory, language |
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| What happens when one is knocked in the knee& you kick |
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Three tunics 1. Fibrous tunic: sclera & cornea 2. Vascular tunic: choroid, ciliary body, and iris 3. Sensory tunic: retina |
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| Ee clear part you see through |
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| Connected to ligaments to lens- smooth muscle |
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| Pigment epithelium, neural area |
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Rods, grey version Cones, colors perceived by fovea centralis |
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| Fish, turtles, izards, birds |
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Visual pigment, Opsin is the protein Retinal is the light absorbing molecule derived from vitamin a |
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| Light absorbing molecule derived from vitamin a |
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Eye protein Allow different wavelengths depending on sensitivity of structure |
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| Excitation of rods light phase |
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Definition
Rhodopsin. Reams down into all- trans retinal + Opsin Bleaching of the pigment |
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Excitation of rods Dark phase |
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| All-trans retinal converts to 11-cis |
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| Sund waves vibrate tympanic membrane |
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| Bones transmit vibration to inner ear |
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| Cochlea contains the organ of corti, the sense organ of hearing |
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| Allows animals to see in lower light |
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| Attached to bone filled with myofibrils |
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| Each myofibril is composed of |
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| Surrounds individual muscle fibers |
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| Groups of muscle fibers grouped together |
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| Wraps around groups of fascicles |
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| Groups of muscle fibers grouped together |
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Surrounds skeletal cells Cell walls- kinda |
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| Cytoplasm of muscle cells |
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Actin G- actin has myosin binding site |
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Troponin complex Wich changes the shape when calcium binds to " troponin c" |
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In cardiac muscles Have desmosomes and gap junctions |
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Sliding filament Mechanism of action |
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Released calcium binds to calmodulin Calcium-calmodulin complex activates kinase Kinase adds a phosphate group from ATP to myosin head Activated myosin binds to actin Thick and thin filaments slide Contraction Muscle relaxes upon removal of calcium |
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Smooth muscle Mechanism of action |
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Calcium increases and binds to calmodulin Calcium-calmodulin complex binds to caldesmon Caldesmon- actin bond is weakened Cross- bridges |
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Same tension Depends on sarcomere length |
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Isotonic contraction Muscle shortens and reduces the angle at the joint |
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Muscle length Isotonic contraction |
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| Source of ATP for skeletal muscle |
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Depends on aerobic system Can use lactic acid waste from skeletal muscles |
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| Type of secretion that affect neighboring cells |
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| Type of secretion that affects neighboring cells |
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| Released onto epithelium via a duct |
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| Type of secretion released into the blood |
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| Taking away in experiment |
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Epinephrine NOrpinephrine Thyroid Melatonin |
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Prostaglandins, leukotrienes
Derivitives of arachidonic acid |
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Testosterone and estrogen
Derivites of cholesterol |
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| Peptide and protein hormones |
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Definition
Insulin and GH
Derivitaves of amino acids Largest number of hormones |
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| Hormones causes changes in target cells |
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Definition
Pasma membrane permeability Protein synthesis Enzyme activity Secretory activity Mitosis |
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| Hormone acts on endocrine tissue to decrease secretion |
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| Down stream product acts on endocrine tissue to decrease secretions |
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Malanocyte stimulating hormone found in pars intermedia of anterior puitary Involved in color change |
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Posterior puitary hormone Smooth muscle contraction in uterus Milk letdown |
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Definition
| posterior puitary hormone |
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Definition
| Regulate secretion of another hormone |
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| Thyroid stimulating hormone |
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Definition
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| Adrenocorticotropid hormone |
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Definition
| Outside of the adrenal cortex |
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| Follicle stimulating hormone |
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Definition
Stimulate ovarian follicle Where egg is developed Tropic |
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Tropic hormone Has an effect of the corpus luteum |
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| Regulates developmental growth of another hormone |
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| Anterior puititary hormone |
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GH, somatotropin, and somatotrophin Anterior puitaraty hormone |
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Noripinephrine and epinephrine From adrenal medulla, target most tissues Release in response to sympathetic stimulation |
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Cortisol, cortisone, corticosterone Steroids From adrenal cortex |
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