Term
| Describe the concept of refinement. |
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Definition
| Strategies that result in procedures that enhance animal wellbeing and minimize pain and distress. |
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Term
| What is an engineering standard? |
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Definition
| A guideline that specifies in detail a method or technique for achieving a desired outcome. |
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Term
| How does The Guide describe a Policy? |
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Definition
| A practical statement of collective wisdom. |
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Term
| Describe The Guide's definition of "should". |
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Definition
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Term
| What types of members should be included in the IACUC? |
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Definition
| A veterinarian, a scientist, one member who is not a scientist, and a public member not affiliated with the institution. |
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Term
| What are the functions of the IACUC? |
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Definition
| Review and approval of proposed animal use protocols, review and approval of proposed significant changes in animal use protocols, regular inspection of animal facilities and use areas, regular review of the program, on-going assessment of animal care and use, and instituting a mechanism for receipt of animal care and use concerns, and reviewing any received concerns. |
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Term
| What does the acronym IACUC stand for? |
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Definition
| Institutional Animal Care and Use Committee |
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Term
| Which statement is an important guideline when using physical restraints? |
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Definition
| Restraint devices are not to be considered normal methods of housing. |
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Term
| How does The Guide define major survival surgery? |
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Definition
| As a general guideline (e.g., laparotomy, thoracotomy, joint replacement, and limb amputation) penetrates and exposes a body cavity, produces substantial impairment of physical or physiologic functions, or involves extensive tissue dissection or transection. |
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Term
| When is multiple major survival surgeries on one animal acceptable? |
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Definition
| If they have been scientifically justified and included in the IACUC-approved protocol (or needed for clinical reasons). |
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Term
| Animals on a fluid regulation protocol should have their body weights recorded at least how often? |
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Definition
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Term
| Who is responsible for providing formal or on-the-job training to personnel caring for animals? |
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Definition
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Term
| TRUE or FALSE: Non-degree training, such as certification programs for lab animal techs and technologists, is an accepted means for obtaining qualifications for working with lab animals. |
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Definition
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Term
| The extent of participation in the occupational health and safety program depends on: |
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Definition
| the number of people who are exposed to hazards, the potential effect of hazards on people and the magnitude of the exposure. |
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Term
| When conducting research using hazardous biologic agents, what publication should be consulted? |
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Definition
| Guidelines for Using Biological Agents in the Laboratory |
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Term
| Who should be involved in determining humane endpoints in a study? |
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Definition
| IACUC, the veterinarian, and the PI. |
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Term
| When is it permissible to use non-pharmaceutical grade substances on animals? |
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Definition
| When permission is granted from the attending veterinarian. |
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Term
| The majority of poikilothermic lab animals are: |
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Definition
| fish and aquatic amphibians |
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Term
| If ventilated caging has adequate filters, the air exhausted may be returned into the room, although it's preferred the air be vented to: |
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Definition
| the facilities exhaust system. |
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Term
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Definition
| The environment made by the animal's primary enclosure, including structural components. |
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Term
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Definition
| Consists of secondary enclosure, room, barn, or outdoor habitat. |
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Term
| Animals adapt to temperature extremes by the following mechanisms: |
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Definition
| Physical, behavioral and metabolic. |
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Term
| What is the recommended number of air changes in an hour in an animal room? |
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Definition
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Term
| Why have albino rodents been used to determine safe illumination levels? |
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Definition
| Albino rodents have eyes that are sensitive to damage caused by high light levels. |
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Term
| Which condition can occur in susceptible animals due to high room illumination levels? |
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Definition
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Term
| TRUE or FALSE: In rats, high humidity levels can cause a condition called ringtail. |
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Definition
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Term
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Definition
| A condition in rats and mice in which necrotic bands appear on the tail as a result of vascular strictures caused by exposure to high temp and low relative humidity (less than 30%). |
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Term
| What is the max sound level above which both auditory and non-auditory effects can result? |
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Definition
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Term
| Social animals should normally be housed with conspecifics. Define conspecifics. |
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Definition
| Animals of the same species |
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Term
| Define environmental enrichment. |
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Definition
| A method of providing animals with the opportunity to behave as they do in the wild, playing, foraging, grooming, and interacting with one another. |
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Term
| Storing animal feed at temps less than _____ °C is recommended. |
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Definition
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Term
| Most dry lab animal diets that are properly stored can be used for _____ after the manufacturing date. |
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Definition
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Term
| Providing nude mice with cotton nesting material may lead to which condition? |
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Definition
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Term
| Cedar shavings are NOT recommended as bedding because they emit: |
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Definition
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Term
| Before it is removed from the facility, hazardous waste should be: |
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Definition
| rendered safe by sterilization or containment. |
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Term
| In general, at least how often should solid bottom cages for rodents typically be sanitized? |
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Definition
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Term
| Primary enclosures and cage accessories, such as cage toys, should be sanitized at least how often? |
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Definition
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Term
| For effective disinfection, the wash and rinse water should be what temp? |
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Definition
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Term
| When new genetic lines of animals are generated, they should be: |
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Definition
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Term
| The ideal pest control program should not include: |
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Definition
| regular use of pesticides. |
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Term
| When inbred animals are used, it is important to monitor their genetic: |
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Definition
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Term
| The environmental enrichment program should be reviewed regularly by: |
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Definition
| The IACUC, the researchers, and the veterinary staff. |
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Term
| TRUE or FALSE: The volume of water in the aquatic tanks in a housing room can affect the temp and relative humidity. |
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Definition
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Term
| What type of aquatic life support system has a biological filter? |
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Definition
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