Term
| what secretes epinephrine |
|
Definition
|
|
Term
| what is the rate limiting steps of steroid production? |
|
Definition
| conversion to pregnenolone |
|
|
Term
| what is the % of cortisol bound to globulin |
|
Definition
|
|
Term
| where is cortisol metabolized |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
fasic and retic growth
increased transport of cholesterol
conversion of choles to pregn |
|
|
Term
|
Definition
| used as a glucocorticoid, together w/MC deficiency |
|
|
Term
| this inhibits production of cortisol |
|
Definition
|
|
Term
| what should be given to pts following long term adrenal suppression? |
|
Definition
| hydrocortisone or prednisone |
|
|
Term
| what drug diagnoses Cushing's? |
|
Definition
|
|
Term
| Which GC drugs are more potent and longer lasting |
|
Definition
| Betamethasone and dexamethasone |
|
|
Term
| These topical drugs have minimal systemic effects |
|
Definition
| Beclomethasone, flunisolide, and memetasone |
|
|
Term
| how can adrenal insufficiency be diagnosed? |
|
Definition
| measuring plasma cortisol after admin of ACTH |
|
|
Term
| What is the treatment regimen for Addison's Dz |
|
Definition
Oral hydrocortisone
Fludrocortisone |
|
|
Term
| Which GC is more toxic, Mitotane or Amphenone B? |
|
Definition
|
|
Term
| This drug blocks conversion of cholesterol to pregnelone |
|
Definition
|
|
Term
| This drug blocks 11-hydroxylation |
|
Definition
|
|
Term
| This drug is used to promote spontaneous abortion |
|
Definition
|
|
Term
|
Definition
| excess secretion of aldosterone |
|
|
Term
| Which MC antag has fewer side effects |
|
Definition
|
|
Term
| This MC antag acts on androgen receptors also |
|
Definition
|
|
Term
| How is the MC receptor specified? |
|
Definition
| conversion of GC to cortisone by 11-Beta hydroxysteroid dehydrogenase |
|
|
Term
| This is the most common synthetic MC |
|
Definition
|
|
Term
| This MC agonist is naturally produced in the zona fasiculata |
|
Definition
|
|
Term
| This antifungal serves as a non-selective inhibitor of steroid synthesis |
|
Definition
|
|
Term
| What is the order of antagonization for Mifepristone |
|
Definition
| progesterone, GC, and sex steroids |
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|
