Term
| Time limited pain elicited by injury of body tissues and activation of nociceptive transducers that remits when underlying pathology resolves. |
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Definition
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Term
| Give 3 classifications of pain with respect to duration of pain. |
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Definition
Severe acute phase - 3 to 5 days
Sub acute - 1 to 4 weeks
Chronic pain - 3 months or more |
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Term
| Important objective finding of acute pain involving abdominal or thoracic regions. |
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Definition
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Term
| 5 options for treatment of acute pain. |
|
Definition
Opioids
Local anesthetics
NSAIDS
Acetaminophen
Tramadol |
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Term
| 2 agents that modulate central processing of pain signal in the brain. |
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Definition
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Term
| 3 agents that work at the dorsal horn to block the pain signal. |
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Definition
Local anesthetics
Opioids
Alpha 2 agonists |
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Term
| Agents that works at the peripheral nerve to block nociceptive transmission of pain. |
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Definition
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Term
| 2 agents that work at the level of the tissue trauma to block nociceptive transmission of pain. |
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Definition
Anti-inflammatory drugs
Local anesthetics |
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Term
| 2 alkaloid types of opioids. |
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Definition
Phenantherenes
Benzylisoquinolones |
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Term
| Antagonist of mu receptors that undoes opioids effect. |
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Definition
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|
Term
| Delta agonists. What do delta receptors do? |
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Definition
| Enkephalins. Modulates mu activity. |
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Term
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Definition
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Term
| Common protocol for use of opioids. |
|
Definition
Initial bolus loading dose
PCA (Patient controlled analgesia) |
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Term
| Opioid that should not be used for PCA. |
|
Definition
| Meperidine. Because it causes seizures (?) |
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Term
|
Definition
IV <1 min
IM 1-5 min
PO 15-60 min |
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|
Term
|
Definition
2 mg IV every 5 minutes until max dose 10-20 mg or comfort
PCA: 1-2mg every 8 minutes |
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Term
| This opioid has no active metabolites and is safe to use in renal failure. |
|
Definition
| Hydromorphone. 5-8 times more potent than morphine. |
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Term
|
Definition
0.1-0.2 mg q5min till max 1-2mg
PCA: 0.1-0.2 mg q8min |
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|
Term
| Fentanyl's relative potency to morphine. |
|
Definition
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|
Term
|
Definition
Acute post op: 25-50 ug q5min
PCA: 10-25 ug q8min |
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|
Term
| Morphine has active metabolites which can accumulate in _____. |
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Definition
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|
Term
| Causes delirium, seizures, myoclonus. Especially in renal failure patients or on patients receiving for more than 3 days. |
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Definition
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|
Term
| 3 most common opioid side effects. |
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Definition
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|
Term
| 2 routes of delivery of local anesthetics. |
|
Definition
Neuraxial - intrathecal or epidural
Regional nerve blockade |
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|
Term
|
Definition
|
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Term
|
Definition
| Acetaminophen and hydromorphone |
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|
Term
|
Definition
|
|
Term
|
Definition
| oxycodone and paracetamol |
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|
Term
| Paracetamol is essentially synonymous with... |
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Definition
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|
Term
Arrange these in order of rate of absorption of local anesthetics, fastest to slowest.
Epidural, intercostal, sciatic, femoral, brachial plexus, caudal |
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Definition
| Intercostal > Caudal > Epidural > Brachial Plexus > Sciatic/Femoral |
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Term
|
Definition
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|
Term
|
Definition
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|
Term
| How are the side effect profiles of COX-2 selective and non-selective NSAIDS different? |
|
Definition
Non-selective induce: gastric ulceration, inhibit platelets, inhibit induction of labor, alter renal function, hypersensitivity.
Selective: Inhibit labor, alter renal function |
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