Term
| Cells responsible for healing by secondary intention |
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Definition
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Term
| way in which myfibroblasts contract a wound |
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Definition
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Term
| Most abundant type of collagen |
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Definition
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Term
| Type of collagen in cartilage |
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Definition
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Term
| Type of collagen in bone and tendons |
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Definition
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Term
| Substrates required for hydroxylation of prolene |
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Definition
| Vit C, Alpha-ketogluterate, oxygen and iron |
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Term
| frequency of proline in normal collagen |
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Definition
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Term
| Order of arrival of cell types in a wound |
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Definition
| Platelets, PMNs, macs, fibroblasts (dominant by day 5), lymphocytes |
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Term
| Factor that stimulates fibroblasts |
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Definition
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Term
| Effects of TGF-B in wound healing |
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Definition
| stimulates fibroblasts and chemtactic agent for PMNs |
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Term
| Effects of PDGF in wound healing |
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Definition
| chemotactic agent for fibroblasts; sitmulates matrix deposition |
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Term
| Source of TNF in healing wound |
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Definition
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|
Term
| Most potent stimulant for TNF production |
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Definition
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Term
| Effects of IL-1 on wound healing |
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Definition
Potentiates TNF
Increases IL-6
Increases endothelium adherence via selectins, ICAM and VCAM |
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Term
| Source of IL-1 in wound healing |
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Definition
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Term
| Responsible for wasting and cachexia |
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Definition
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Term
| Effects of TNF on wound healing |
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Definition
| recruits and activates PMNs which leads to more cytokine production |
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Term
| Cytokine responsible for fever |
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Definition
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Term
| Milieu of acute phase response |
|
Definition
Increase: CRP, amyloid, fibrinogen, haptoglobin, ceruloplasmin, and Alpha-1 antitrypsin
Decrease: albumin, transferrin and fibronectin |
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